3IHR
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![BU of 3ihr by Molmil](/molmil-images/mine/3ihr) | Crystal Structure of Uch37 | 分子名称: | FORMIC ACID, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-07-30 | 公開日 | 2009-08-11 | 最終更新日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural characterization of human Uch37. Proteins, 80, 2012
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2J90
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![BU of 2j90 by Molmil](/molmil-images/mine/2j90) | Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6) | 分子名称: | 1,2-ETHANEDIOL, 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, CHLORIDE ION, ... | 著者 | Turnbull, A.P, Berridge, G, Fedorov, O, Pike, A.C.W, Savitsky, P, Eswaran, J, Papagrigoriou, E, Ugochukwa, E, von Delft, F, Gileadi, O, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | 登録日 | 2006-10-31 | 公開日 | 2006-11-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27, 2008
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1IB8
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![BU of 1ib8 by Molmil](/molmil-images/mine/1ib8) | SOLUTION STRUCTURE AND FUNCTION OF A CONSERVED PROTEIN SP14.3 ENCODED BY AN ESSENTIAL STREPTOCOCCUS PNEUMONIAE GENE | 分子名称: | CONSERVED PROTEIN SP14.3 | 著者 | Yu, L, Gunasekera, A.H, Mack, J, Olejniczak, E.T, Chovan, L.E, Ruan, X, Towne, D.L, Lerner, C.G, Fesik, S.W. | 登録日 | 2001-03-27 | 公開日 | 2002-03-27 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | SOLUTION STRUCTURE AND FUNCTION OF A CONSERVED PROTEIN SP14.3 ENCODED BY AN ESSENTIAL STREPTOCOCCUS PNEUMONIAE GENE J.Mol.Biol., 311, 2001
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1IBM
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![BU of 1ibm by Molmil](/molmil-images/mine/1ibm) | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | 登録日 | 2001-03-28 | 公開日 | 2001-05-04 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 2001
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2Y3F
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![BU of 2y3f by Molmil](/molmil-images/mine/2y3f) | Traptavidin, biotin bound form | 分子名称: | BIOTIN, GLYCEROL, STREPTAVIDIN | 著者 | Chivers, C.E, Koner, A.L, Lowe, E.D, Howarth, M. | 登録日 | 2010-12-20 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.493 Å) | 主引用文献 | How the Biotin-Streptavidin Interaction Was Made Even Stronger: Investigation Via Crystallography and a Chimeric Tetramer. Biochem.J., 435, 2011
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6MMS
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![BU of 6mms by Molmil](/molmil-images/mine/6mms) | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | 登録日 | 2018-10-01 | 公開日 | 2018-11-28 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (5.38 Å) | 主引用文献 | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
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6MMV
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![BU of 6mmv by Molmil](/molmil-images/mine/6mmv) | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* Extracellular Domain in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | 登録日 | 2018-10-01 | 公開日 | 2018-11-28 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.71 Å) | 主引用文献 | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
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2C94
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![BU of 2c94 by Molmil](/molmil-images/mine/2c94) | LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) 1,1 difluoropentane-1- PHOSPHATE | 分子名称: | 3-(1,3,7-TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL) 1,1 DIFLUOROPENTANE-1-PHOSPHATE, 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, POTASSIUM ION | 著者 | Morgunova, E, Illarionov, B, Jin, G, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | 登録日 | 2005-12-09 | 公開日 | 2006-12-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J., 273, 2006
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6F0T
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![BU of 6f0t by Molmil](/molmil-images/mine/6f0t) | Crystal structure of Pizza6-SFW | 分子名称: | GLYCEROL, Pizza6-SFW | 著者 | Noguchi, H, De Zitter, E, Van Meervelt, L, Voet, A.R.D. | 登録日 | 2017-11-20 | 公開日 | 2018-03-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Design of tryptophan-containing mutants of the symmetrical Pizza protein for biophysical studies. Biochem. Biophys. Res. Commun., 497, 2018
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6F1U
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![BU of 6f1u by Molmil](/molmil-images/mine/6f1u) | N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | 登録日 | 2017-11-23 | 公開日 | 2018-01-17 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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2ISW
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![BU of 2isw by Molmil](/molmil-images/mine/2isw) | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | 著者 | Galkin, A, Herzberg, O. | 登録日 | 2006-10-18 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J.Biol.Chem., 282, 2007
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3LM5
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![BU of 3lm5 by Molmil](/molmil-images/mine/3lm5) | Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Serine/threonine-protein kinase 17B | 著者 | Ugochukwu, E, Soundararajan, M, Rellos, P, Fedorov, O, Phillips, C, Wang, J, Hapka, E, Filippakopoulos, P, Chaikuad, A, Pike, A.C.W, Carpenter, L, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-01-29 | 公開日 | 2010-03-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. J.Med.Chem., 63, 2020
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2XYN
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![BU of 2xyn by Molmil](/molmil-images/mine/2xyn) | HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680 | 分子名称: | CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, SODIUM ION, ... | 著者 | Salah, E, Ugochukwu, E, Elkins, J.M, Barr, A.J, Shrestha, B, Savitsky, P, Mahajan, P, Muniz, J.R.C, Yue, W.W, Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-18 | 公開日 | 2010-12-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal Structures of Abl-Related Gene (Abl2) in Complex with Imatinib, Tozasertib (Vx-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J.Med.Chem., 54, 2011
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6F58
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![BU of 6f58 by Molmil](/molmil-images/mine/6f58) | Crystal structure of human Brachyury (T) in complex with DNA | 分子名称: | Brachyury protein, DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*TP*T)-3'), SODIUM ION | 著者 | Newman, J.A, Gavard, A.E, Krojer, T, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2017-12-01 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | 主引用文献 | Crystal structure of human Brachyury (T) in complex with DNA To Be Published
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8T3I
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![BU of 8t3i by Molmil](/molmil-images/mine/8t3i) | Crystal structure of mutant exfoliative toxin C (ExhC) from Mammaliicoccus sciuri | 分子名称: | Exfoliative toxin C | 著者 | Gismene, C, Calil, F.A, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. | 登録日 | 2023-06-07 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024
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8FO1
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![BU of 8fo1 by Molmil](/molmil-images/mine/8fo1) | |
6MMN
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![BU of 6mmn by Molmil](/molmil-images/mine/6mmn) | Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 8.0 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. | 登録日 | 2018-10-01 | 公開日 | 2018-11-28 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (7.51 Å) | 主引用文献 | Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018
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6F6P
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![BU of 6f6p by Molmil](/molmil-images/mine/6f6p) | |
3RW9
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![BU of 3rw9 by Molmil](/molmil-images/mine/3rw9) | Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine | 分子名称: | 5'-S-(3-aminopropyl)-5'-thioadenosine, Spermidine synthase | 著者 | Seckute, J, McCloskey, D.E, Thomas, H.J, Secrist III, J.A, Pegg, A.E, Ealick, S.E. | 登録日 | 2011-05-08 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine. Protein Sci., 20, 2011
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2XZO
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![BU of 2xzo by Molmil](/molmil-images/mine/2xzo) | Upf1 helicase - RNA complex | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | 登録日 | 2010-11-26 | 公開日 | 2011-03-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2. Mol.Cell, 41, 2011
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6F9H
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![BU of 6f9h by Molmil](/molmil-images/mine/6f9h) | Crystal structure of Barley Beta-Amylase complexed with 4-S-alpha-D-glucopyranosyl-(1,4-dideoxy-4-thio-nojirimycin) | 分子名称: | 1,4-dideoxy-4-thio-nojirimycin, Beta-amylase, CHLORIDE ION, ... | 著者 | Moncayo, M.A, Rodrigues, L.L, Stevenson, C.E.M, Ruzanski, C, Rejzek, M, Lawson, D.M, Angulo, J, Field, R.A. | 登録日 | 2017-12-14 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis, biological and structural analysis of prospective glycosyl-iminosugar prodrugs: impact on germination To be published
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5AEK
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![BU of 5aek by Molmil](/molmil-images/mine/5aek) | Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W | 分子名称: | SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1 | 著者 | Gallego, P, Grana-Montes, R, Espargaro, A, Castillo, V, Torrent, J, Lange, R, Papaleo, E, Lindorff-Larsend, K, Ventura, S, Reverter, D. | 登録日 | 2014-12-23 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Stepping Back and Forward on Sumo Folding Evolution To be Published
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4R0N
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![BU of 4r0n by Molmil](/molmil-images/mine/4r0n) | Hexagonal form of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis | 分子名称: | Phosphopantetheine adenylyltransferase, SULFATE ION | 著者 | Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P. | 登録日 | 2014-08-01 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Hexagonal form of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis TO BE PUBLISHED
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3LZO
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![BU of 3lzo by Molmil](/molmil-images/mine/3lzo) | Crystal Structure Analysis of the copper-reconstituted P19 protein from Campylobacter jejuni at 1.65 A at pH 10.0 | 分子名称: | COPPER (II) ION, P19 protein, SULFATE ION | 著者 | Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P. | 登録日 | 2010-03-01 | 公開日 | 2010-07-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni. J.Mol.Biol., 401, 2010
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6H9S
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![BU of 6h9s by Molmil](/molmil-images/mine/6h9s) | |