2ISW

Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate

Summary for 2ISW

Entry DOI	10.2210/pdb2isw/pdb
Related	2ISV
Descriptor	Putative fructose-1,6-bisphosphate aldolase, ZINC ION, PHOSPHOGLYCOLOHYDROXAMIC ACID, ... (4 entities in total)
Functional Keywords	class ii fructose-1, 6-bisphosphate aldolase, glycolytic pathway, giardia lamblia, drug target, lyase
Biological source	Giardia intestinalis
Total number of polymer chains	2
Total formula weight	70824.03
Authors	Galkin, A.,Herzberg, O. (deposition date: 2006-10-18, release date: 2006-12-12, Last modification date: 2023-08-30)
Primary citation	Galkin, A.,Kulakova, L.,Melamud, E.,Li, L.,Wu, C.,Mariano, P.,Dunaway-Mariano, D.,Nash, T.E.,Herzberg, O. Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J.Biol.Chem., 282:4859-4867, 2007 Cited by PubMed: 17166851 DOI: 10.1074/jbc.M609534200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation