2ISV
Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate
Summary for 2ISV
Entry DOI | 10.2210/pdb2isv/pdb |
Related | 2ISW |
Descriptor | Putative fructose-1,6-bisphosphate aldolase, ZINC ION, PHOSPHOGLYCOLOHYDROXAMIC ACID, ... (4 entities in total) |
Functional Keywords | class ii fructose-1, 6-bisphosphate aldolase, glycolytic pathway, giardia lamblia, drug target, lyase |
Biological source | Giardia intestinalis |
Total number of polymer chains | 2 |
Total formula weight | 71060.48 |
Authors | Galkin, A.,Herzberg, O. (deposition date: 2006-10-18, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Galkin, A.,Kulakova, L.,Melamud, E.,Li, L.,Wu, C.,Mariano, P.,Dunaway-Mariano, D.,Nash, T.E.,Herzberg, O. Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia. J.Biol.Chem., 282:4859-4867, 2007 Cited by PubMed: 17166851DOI: 10.1074/jbc.M609534200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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