2XZO

Upf1 helicase - RNA complex

Summary for 2XZO

• Entry DOI: 10.2210/pdb2xzo/pdb
• Related: 2GJK 2GK6 2GK7 2IYK 2WJV 2WJY 2XZP
• Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', PENTAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: hydrolase-rna complex, nmd, rna degradation, allosteric regulation, hydrolase/rna
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: Q92900
• Total number of polymer chains: 2
• Total formula weight: 73420.23

Authors

Chakrabarti, S.,Jayachandran, U.,Bonneau, F.,Fiorini, F.,Basquin, C.,Domcke, S.,Le Hir, H.,Conti, E. (deposition date: 2010-11-26, release date: 2011-03-30, Last modification date: 2023-12-20)

• Primary citation: Chakrabarti, S.,Jayachandran, U.,Bonneau, F.,Fiorini, F.,Basquin, C.,Domcke, S.,Le Hir, H.,Conti, E.; Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.; Mol.Cell, 41:693-, 2011; PubMed: 21419344; DOI: 10.1016/J.MOLCEL.2011.02.010

Experimental method

X-RAY DIFFRACTION (2.395 Å)