2XZO

Upf1 helicase - RNA complex

Summary for 2XZO

Related2WJV 2WJY 2IYK 2XZP 2GJK 2GK7 2GK6
DescriptorREGULATOR OF NONSENSE TRANSCRIPTS 1, 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', PENTAETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywordshydrolase-rna complex, nmd, rna degradation, allosteric regulation, hydrolase/rna
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationCytoplasm Q92900
Total number of polymer chains2
Total molecular weight73420.23
Authors
Chakrabarti, S.,Jayachandran, U.,Bonneau, F.,Fiorini, F.,Basquin, C.,Domcke, S.,Le Hir, H.,Conti, E. (deposition date: 2010-11-26, release date: 2011-03-30, Last modification date: 2017-07-12)
Primary citation
Chakrabarti, S.,Jayachandran, U.,Bonneau, F.,Fiorini, F.,Basquin, C.,Domcke, S.,Le Hir, H.,Conti, E.
Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41:693-, 2011
PubMed: 21419344 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2011.02.010
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.395 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.22290.2%1.1%4.0%0.62MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report