PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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8ETE	Bile Salt Hydrolase from B. longum with covalent inhibitor bound 分子名称: (5R)-1-fluoro-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]hexan-2-one (non-preferred name), Conjugated bile acid hydrolase 著者 Walker, M.E, Redinbo, M.R. 登録日 2022-10-17 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity To Be Published
3IMR	Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dichlorostyryl)phenol 分子名称: 2,6-dibromo-4-[(E)-2-(2,6-dichlorophenyl)ethenyl]phenol, Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2009-08-11 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010
1RAC	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
2UAG	UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE), ... 著者 Bertrand, J, Fanchon, E, Dideberg, O. 登録日 1999-02-23 公開日 2000-02-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Determination of the MurD mechanism through crystallographic analysis of enzyme complexes. J.Mol.Biol., 289, 1999
6EQI	Structure of PINK1 bound to ubiquitin 分子名称: GLYCEROL, Nb696, Serine/threonine-protein kinase PINK1, ... 著者 Schubert, A.F, Gladkova, C, Pardon, E, Wagstaff, J.L, Freund, S.M.V, Steyaert, J, Maslen, S, Komander, D. 登録日 2017-10-13 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of PINK1 in complex with its substrate ubiquitin. Nature, 552, 2017
6EQV	X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Phac-Cit-Val-Arg-Amba 分子名称: CALCIUM ION, CHLORIDE ION, Furin, ... 著者 Dahms, S.O, Than, M.E. 登録日 2017-10-16 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket. Biochemistry, 57, 2018
8F2M	Phi-29 scaffolding protein bound to intermediate-state MCP 分子名称: Capsid assembly scaffolding protein, Major capsid protein 著者 Woodson, M.E, Morais, M.C, Jardine, P.J, Scott, S.D. 登録日 2022-11-08 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Scaffold Oligomers Control Prohead Expansion To Be Published
5AP9	Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Skjold-Joergensen, J, Vind, J, Moroz, O.V, Blagova, E.V, Bhatia, V.K, Svendsen, A, Wilson, K.S, Bjerrum, M.J. 登録日 2015-09-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function. Biochim. Biophys. Acta, 1865, 2017
5ARI	Bovine mitochondrial ATP synthase state 2b 分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... 著者 Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. 登録日 2015-09-24 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015
3NWF	Glycoprotein B from Herpes simplex virus type 1, low-pH 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, MESO-ERYTHRITOL, ... 著者 Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. 登録日 2010-07-09 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
3EQ1	The Crystal Structure of Human Porphobilinogen Deaminase at 2.8A resolution 分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase, SULFATE ION 著者 Kolstoe, S.E, Gill, R, Mohammed, F, Wood, S.P. 登録日 2008-09-30 公開日 2009-03-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria Biochem.J., 420, 2009
6J9Q	Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP. 分子名称: GLYCEROL, Glycerol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. 登録日 2019-01-24 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Reaction mechanism of the reverse reaction of African human trypanosomes glycerol kinase. To Be Published
6EB4	OhrB (Organic Hydroperoxide Resistance protein) from Chromobacterium violaceum 分子名称: DI(HYDROXYETHYL)ETHER, Organic hydroperoxide resistance protein 著者 Domingos, R.M, Teixeira, R.D, Alegria, T.G.P, Vieira, P.S, Murakami, M.T, Netto, L.E.S. 登録日 2018-08-04 公開日 2020-02-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Substrate and product-assisted catalysis: molecular aspects behind structural switches along Organic Hydroperoxide Resistance Protein catalytic cycle Acs Catalysis, 2020
6JAF	Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with PPi (pyrophosphatase reaction) 分子名称: GLYCEROL, Glycerol kinase, PYROPHOSPHATE 2- 著者 Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, Bringaud, F, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. 登録日 2019-01-24 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Glycerol Kinase of African Human Trypanosomes Possesses a Pyrophosphatase Activity. To Be Published
6EM4	State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... 著者 Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. 登録日 2017-10-01 公開日 2017-12-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
1RAD	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
6EBP	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form 分子名称: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ... 著者 Palowitch, G.M, Boal, A.K. 登録日 2018-08-06 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7NMO	Crystal structure of beta-2-microglobulin D76A mutant 分子名称: Beta-2-microglobulin 著者 Guthertz, N. 登録日 2021-02-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
2ISJ	BluB bound to oxidized FMN 分子名称: BluB, FLAVIN MONONUCLEOTIDE 著者 Larsen, N.A, Taga, M.E, Howard-Jones, A.R, Walsh, C.T, Walker, G.C. 登録日 2006-10-17 公開日 2007-03-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature, 446, 2007
4Q2M	Structure of the E. coli YajR Transporter YAM Domain Combined Iodine 分子名称: ACETIC ACID, CADMIUM ION, IODIDE ION, ... 著者 Zhang, X.C. 登録日 2014-04-09 公開日 2014-07-09 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.489 Å) 主引用文献 Atomic resolution structure of the E. coli YajR transporter YAM domain. Biochem.Biophys.Res.Commun., 450, 2014
7NMT	Crystal structure of beta-2-microglobulin D76G mutant 分子名称: Beta-2-microglobulin 著者 Guthertz, N. 登録日 2021-02-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
2RLU	The Three Dimensional Structure of the Moorella thermoacetica Selenocysteine Insertion Sequence RNA Hairpin and its Interaction with the Elongation factor SelB 分子名称: RNA (5'-R(*GP*GP*UP*UP*GP*CP*GP*GP*GP*UP*CP*UP*CP*GP*CP*AP*AP*CP*C)-3') 著者 Beribisky, A.V, Tavares, T.J, Amborski, A.N, Motamed, M, Johnson, A.E, Mark, T.L, Johnson, P.E. 登録日 2007-08-21 公開日 2008-02-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The three-dimensional structure of the Moorella thermoacetica selenocysteine insertion sequence RNA hairpin and its interaction with the elongation factor SelB Rna, 13, 2007
7NMV	Crystal structure of beta-2-microglobulin D76Q mutant 分子名称: Beta-2-microglobulin 著者 Guthertz, N. 登録日 2021-02-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
7NMY	Crystal structure of beta-2-microglobulin D76Y mutant 分子名称: Beta-2-microglobulin 著者 Guthertz, N. 登録日 2021-02-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
7N8P	CLC-ec1 at pH 4.5 100mM Cl Swap 分子名称: H(+)/Cl(-) exchange transporter ClcA 著者 Fortea, E, Boudker, O, Accardi, A. 登録日 2021-06-15 公開日 2022-11-16 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Structural basis of common gate activation in CLC transporters To Be Published

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