5AOM
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![BU of 5aom by Molmil](/molmil-images/mine/5aom) | Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan883 | 分子名称: | CELLULAR TUMOR ANTIGEN P53, GLYCEROL, N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide, ... | 著者 | Joerger, A.C, Boeckler, F.M, Wilcken, R. | 登録日 | 2015-09-10 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53. Structure, 23, 2015
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2H98
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5AOK
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![BU of 5aok by Molmil](/molmil-images/mine/5aok) | Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan7099 | 分子名称: | 5-[2-cyclopropyl-5-(1H-pyrrol-1-yl)-1,3-oxazol-4-yl]-1H-1,2,3,4-tetrazole, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ... | 著者 | Joerger, A.C. | 登録日 | 2015-09-10 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53. Structure, 23, 2015
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5AOL
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2H99
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![BU of 2h99 by Molmil](/molmil-images/mine/2h99) | Crystal structure of the effector binding domain of a BenM variant (R156H,T157S) | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. | 登録日 | 2006-06-09 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009
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2H9B
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![BU of 2h9b by Molmil](/molmil-images/mine/2h9b) | Crystal structure of the effector binding domain of a BenM variant (BenM R156H/T157S) | 分子名称: | CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION | 著者 | Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. | 登録日 | 2006-06-09 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009
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6YVZ
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![BU of 6yvz by Molmil](/molmil-images/mine/6yvz) | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic JLS-367 | 分子名称: | 4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | 著者 | Chowdhury, R, Sorensen, J.L, Schofield, C.J. | 登録日 | 2020-04-29 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6Z8K
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![BU of 6z8k by Molmil](/molmil-images/mine/6z8k) | La Crosse virus polymerase at elongation mimicking stage | 分子名称: | La Crosse virus 3' vRNA (1-16), La Crosse virus 5' vRNA (9-16), La Crosse virus 5' vRNA 1-10, ... | 著者 | Arragain, B, Effantin, G, Schoehn, G, Cusack, S, Malet, H. | 登録日 | 2020-06-02 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nat Commun, 11, 2020
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5LI4
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![BU of 5li4 by Molmil](/molmil-images/mine/5li4) | bacteriophage phi812K1-420 tail sheath protein after contraction | 分子名称: | tail sheath protein | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6YW0
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6YVX
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![BU of 6yvx by Molmil](/molmil-images/mine/6yvx) | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic BB-287 | 分子名称: | 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | 著者 | Chowdhury, R, Banerji, B, Schofield, C.J. | 登録日 | 2020-04-28 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6YW4
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5LI2
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![BU of 5li2 by Molmil](/molmil-images/mine/5li2) | bacteriophage phi812K1-420 tail sheath and tail tube protein in native tail | 分子名称: | Phage-like element PBSX protein XkdM, tail sheath protein | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6Z6B
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![BU of 6z6b by Molmil](/molmil-images/mine/6z6b) | Structure of full-length La Crosse virus L protein (polymerase) | 分子名称: | RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ... | 著者 | Cusack, S, Gerlach, P, Reguera, J. | 登録日 | 2020-05-28 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.961 Å) | 主引用文献 | Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nat Commun, 11, 2020
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6Z1R
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![BU of 6z1r by Molmil](/molmil-images/mine/6z1r) | bovine ATP synthase F1-peripheral stalk domain, state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-05-14 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZJ8
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5LIJ
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![BU of 5lij by Molmil](/molmil-images/mine/5lij) | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | 分子名称: | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6Z6G
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![BU of 6z6g by Molmil](/molmil-images/mine/6z6g) | Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage | 分子名称: | 3'vRNA 1-16, 5'vRNA 1-10, 5'vRNA 9-16, ... | 著者 | Arragain, B, Effantin, G, Gerlach, P, Reguera, J, Schoehn, G, Cusack, S, Malet, H. | 登録日 | 2020-05-28 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nat Commun, 11, 2020
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5MC6
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![BU of 5mc6 by Molmil](/molmil-images/mine/5mc6) | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | 登録日 | 2016-11-09 | 公開日 | 2017-01-18 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science, 354, 2016
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5LII
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![BU of 5lii by Molmil](/molmil-images/mine/5lii) | bacteriophage phi812K1-420 major capsid protein | 分子名称: | Major capsid protein | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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4WRB
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![BU of 4wrb by Molmil](/molmil-images/mine/4wrb) | Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-190) | 分子名称: | 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | 登録日 | 2014-10-23 | 公開日 | 2015-03-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
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6ID0
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![BU of 6id0 by Molmil](/molmil-images/mine/6id0) | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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4WR8
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![BU of 4wr8 by Molmil](/molmil-images/mine/4wr8) | Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) | 分子名称: | 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... | 著者 | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | 登録日 | 2014-10-23 | 公開日 | 2015-03-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
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6ICZ
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![BU of 6icz by Molmil](/molmil-images/mine/6icz) | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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3LOC
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![BU of 3loc by Molmil](/molmil-images/mine/3loc) | Crystal structure of putative transcriptional regulator ycdc | 分子名称: | HTH-type transcriptional regulator rutR, URACIL | 著者 | Patskovsky, Y.V, Knapik, A.A, Mennella, V, Burley, S.K, Minor, W, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2010-02-03 | 公開日 | 2010-03-16 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Hypothetical Transcriptional Regulator Ycdc from Escherichia Coli To be Published
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