PDB: 22634 件ウェブページステータス検索Chemie searchBIRD

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2HW2	Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin 分子名称: GLYCINE, RIFAMPICIN, Rifampin ADP-ribosyl transferase 著者 Baysarowich, J, Wright, G.D, Junop, M. 登録日 2006-07-31 公開日 2007-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr. Proc.Natl.Acad.Sci.Usa, 105, 2008
4NXI	Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein 著者 Albesa-Jove, D, Urresti, S, Comino, N, Guerin, M.E. 登録日 2013-12-09 公開日 2014-10-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. Acs Chem.Biol., 9, 2014
2OZ5	Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS 分子名称: Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID 著者 Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC) 登録日 2007-02-23 公開日 2007-05-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB. Structure, 15, 2007
2FP2	Secreted Chorismate Mutase from Mycobacterium tuberculosis 分子名称: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Chorismate mutase 著者 Okvist, M, Dey, R, Sasso, S, Grahn, E, Kast, P, Krengel, U. 登録日 2006-01-15 公開日 2006-03-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed J.Mol.Biol., 357, 2006
3X3M	Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121 分子名称: CALCIUM ION, ESX-1 secretion system protein EccB1 著者 Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. 登録日 2015-01-24 公開日 2015-12-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase. Faseb J., 29, 2015
2XTA	Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase in complex with acetyl-CoA (triclinic form) 分子名称: 2-OXOGLUTARATE DECARBOXYLASE, ACETYL COENZYME *A, CALCIUM ION, ... 著者 Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M. 登録日 2010-10-05 公開日 2011-06-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism. Chem.Biol., 18, 2011
1XSF	Solution structure of a resuscitation promoting factor domain from Mycobacterium tuberculosis 分子名称: Probable resuscitation-promoting factor rpfB 著者 Cohen-Gonsaud, M, Barthe, P, Henderson, B, Ward, J, Roumestand, C, Keep, N.H. 登録日 2004-10-19 公開日 2005-02-15 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes Nat.Struct.Mol.Biol., 12, 2005
1XXU	Crystal Structure of AhpE from Mycrobacterium tuberculosis, a 1-Cys peroxiredoxin 分子名称: Hypothetical protein Rv2238c/MT2298 著者 Li, S, Peterson, N.A, Kim, M.Y, Kim, C.Y, Hung, L.W, Yu, M, Lekin, T, Segelke, B.W, Lott, J.S, Baker, E.N, TB Structural Genomics Consortium (TBSGC) 登録日 2004-11-08 公開日 2005-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin J.Mol.Biol., 346, 2005
4DQV	Crystal structure of reductase (R) domain of non-ribosomal peptide synthetase from Mycobacterium tuberculosis 分子名称: PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) 著者 Haque, A.S, Panjikar, S, Sankaranarayanan, R. 登録日 2012-02-16 公開日 2012-06-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc.Natl.Acad.Sci.USA, 109, 2012
1Y3I	Crystal Structure of Mycobacterium tuberculosis NAD kinase-NAD complex 分子名称: GLYCEROL, Inorganic polyphosphate/ATP-NAD kinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Mori, S, Yamasaki, M, Maruyama, Y, Momma, K, Kawai, S, Hashimoto, W, Mikami, B, Murata, K. 登録日 2004-11-25 公開日 2005-01-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase-NAD complex Biochem.Biophys.Res.Commun., 327, 2005
2FP1	Secreted Chorismate Mutase from Mycobacterium tuberculosis 分子名称: Chorismate mutase, LEAD (II) ION 著者 Okvist, M, Dey, R, Sasso, S, Grahn, E, Kast, P, Krengel, U. 登録日 2006-01-15 公開日 2006-03-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed J.Mol.Biol., 357, 2006
7YY9	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 13 分子名称: 2-azanyl-4-chloranyl-benzenecarbonitrile, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.485 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YYB	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 15 分子名称: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY6	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 10 分子名称: 6-methylpyridine-2,3-dicarboxylic acid, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.506 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY3	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 7 分子名称: 5-fluoroindole-2-carboxylic acid, MAGNESIUM ION, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.535 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YWM	Crystal structure of Mycobacterium abcessus Phosphopantetheine adenylyltransferase in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-14 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.624 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YYC	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 16 分子名称: 2-indol-1-ylethanoic acid, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY7	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 11 分子名称: 3-hydroxynaphthalene-2-carboxylic acid, Phosphopantetheine adenylyltransferase, SULFATE ION 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.538 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY2	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Compound 20 分子名称: 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY8	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 12 分子名称: (2R)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid, 3-(INDOL-3-YL) LACTATE, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.516 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YY4	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 8 分子名称: 6-fluoranylnaphthalene-2-carboxylic acid, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.671 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
3FSX	Structure of tetrahydrodipicolinate N-succinyltransferase (Rv1201c; DapD) from Mycobacterium tuberculosis 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, MAGNESIUM ION, ... 著者 Schuldt, L, Weyand, S, Kefala, G, Weiss, M.S. 登録日 2009-01-12 公開日 2009-06-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism. J.Mol.Biol., 389, 2009
7YYA	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 14 分子名称: 3-indol-1-ylpropanoic acid, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.807 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
7YXZ	Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Coenzyme A 分子名称: COENZYME A, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, Coyne, A.G, Blundell, T.L. 登録日 2022-02-17 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.779 Å) 主引用文献 Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9, 2022
1YS6	Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis 分子名称: CALCIUM ION, GLYCEROL, Transcriptional regulatory protein prrA 著者 Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2005-02-07 公開日 2006-02-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis To be published

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