PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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3QTE	Crystal structure of human alpha-defensin 6 (H27W mutant) 分子名称: CHLORIDE ION, Defensin-6, GLYCEROL 著者 Pazgier, M, Lu, W. 登録日 2011-02-22 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science, 337, 2012
5YPB	p62/SQSTM1 ZZ domain with His-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
5YPH	p62/SQSTM1 ZZ domain with Ile-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.629 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
5YP8	p62/SQSTM1 ZZ domain with Arg-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.448 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
5YPG	p62/SQSTM1 ZZ domain with Leu-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
7U69	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Phenethyl Piperidine-4-acrylhydroxamic Acid Inhibitor 分子名称: (2E)-N-hydroxy-3-[1-(2-phenylethyl)piperidin-4-yl]prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-03 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
7U3M	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with N-methylpiperazine Benzhydroxamic Acid 分子名称: N-hydroxy-4-[(4-methylpiperazin-1-yl)methyl]benzamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-02-27 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
7U6A	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor 分子名称: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-03 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
5MT3	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-06 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT9	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-07 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
7U6B	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Indolethyl Piperidine-4-acrylhydroxamic Acid Inhibitor 分子名称: (2E)-N-hydroxy-3-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-03 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
5YPF	p62/SQSTM1 ZZ domain with Trp-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.951 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
5JST	MBP fused MDV1 coiled coil 分子名称: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein,Mitochondrial division protein 1, ... 著者 Kim, B.-W, Song, H.K. 登録日 2016-05-09 公開日 2017-03-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 ACCORD: an assessment tool to determine the orientation of homodimeric coiled-coils. Sci Rep, 7, 2017
5NJR	Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 4ET8 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... 著者 Oberthuer, D, Meents, A, Beyerlein, K.R, Chapman, H.N, Lieseke, J. 登録日 2017-03-29 公開日 2017-10-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mix-and-diffuse serial synchrotron crystallography. IUCrJ, 4, 2017
5YPE	p62/SQSTM1 ZZ domain with Tyr-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
7U59	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Piperidine-4-hydroxamic acid Inhibitor 分子名称: 1,2-ETHANEDIOL, 1-[2-(benzylamino)ethyl]-N-hydroxypiperidine-4-carboxamide, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-01 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement. Chembiochem, 23, 2022
5YPA	p62/SQSTM1 ZZ domain with Lys-peptide 分子名称: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
5YP7	p62/SQSTM1 ZZ domain 分子名称: Sequestosome-1, ZINC ION 著者 Kwon, D.H, Kim, L, Song, H.K. 登録日 2017-11-01 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.424 Å) 主引用文献 Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
1NE3	Solution structure of ribosomal protein S28E from Methanobacterium Thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH0256_1_68; Northeast Structural Genomics Target TT744 分子名称: 30S ribosomal protein S28E 著者 Wu, B, Pineda-Lucena, A, Yee, A, Cort, J.R, Ramelot, T.A, Kennedy, M, Edwards, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) 登録日 2002-12-10 公開日 2003-12-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum. Protein Sci., 12, 2003
5JU7	DNA BINDING DOMAIN OF E.COLI CADC 分子名称: Transcriptional activator CadC, ZINC ION 著者 Janowski, R, Schlundt, A, Sattler, M, Niessing, D. 登録日 2016-05-10 公開日 2017-04-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator. Sci Rep, 7, 2017
1OVO	CRYSTALLOGRAPHIC REFINEMENT OF JAPANESE QUAIL OVOMUCOID, A KAZAL-TYPE INHIBITOR, AND MODEL BUILDING STUDIES OF COMPLEXES WITH SERINE PROTEASES 分子名称: OVOMUCOID THIRD DOMAIN 著者 Weber, E, Papamokos, E, Bode, W, Huber, R, Kato, I, Laskowskijunior, M. 登録日 1982-01-18 公開日 1982-05-26 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases. J.Mol.Biol., 158, 1982
8AXW	The structure of mouse AsterC (GramD1c) with Ezetimibe 分子名称: (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, CHLORIDE ION, ETHANOL, ... 著者 Fairall, L, Xiao, X, Burger, L, Tontonoz, P, Schwabe, J.W.R. 登録日 2022-09-01 公開日 2023-09-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake. Science, 382, 2023
5UIC	Structure of the Francisella response regulator receiver domain, QseB 分子名称: Two-component response regulator 著者 Allen, C.L, Milton, M.E, Cavanagh, J. 登録日 2017-01-13 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.487 Å) 主引用文献 Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds. Mol. Microbiol., 106, 2017
8BAH	Human Mre11-Nbs1 complex 分子名称: Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin 著者 Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. 登録日 2022-10-11 公開日 2023-01-11 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (4.13 Å) 主引用文献 Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
5K5M	Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ... 著者 Arora, R, Benson, T.E. 登録日 2016-05-23 公開日 2016-08-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling. Plos Pathog., 12, 2016

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