PDB: 42545 件ウェブページステータス検索Chemie searchBIRD

---

9CG9	Cryo-EM structure of an HMGB1 box bound to nucleosome at SHL-2 分子名称: High mobility group protein B1, Histone H2A type 1, Histone H2B, ... 著者 Chio, U.S, Saunders, H.S, Narlikar, G.J, Cheng, Y. 登録日 2024-06-28 公開日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Competition between HMGB1 and H1 on nucleosomes tunes dynamics within condensed chromatin To Be Published
4L5I	Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition 分子名称: Transcriptional regulator LsrR 著者 Ryu, K.S, Ha, J.H, Eo, Y. 登録日 2013-06-11 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition. J.Am.Chem.Soc., 135, 2013
5X22	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zhang, Y, Ebright, R. 登録日 2017-01-29 公開日 2017-07-05 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
5J7J	NMR Derived Structure of Ca2+ Calmodulin bound to Phosphorylated PSD-95 分子名称: CALCIUM ION, Calmodulin, Disks large homolog 4 著者 Turner, M.L, Ames, J.B, Anderson, D.E. 登録日 2016-04-06 公開日 2017-10-25 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Ca2+/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down. Embo J., 37, 2018
4L51	Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition 分子名称: 5-O-phosphono-alpha-D-ribofuranose, Transcriptional regulator LsrR 著者 Ryu, K.S, Ha, J.H, Eo, Y. 登録日 2013-06-10 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition. J.Am.Chem.Soc., 135, 2013
4L5J	Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition 分子名称: 5-O-phosphono-alpha-D-ribofuranose, Transcriptional regulator LsrR 著者 Ryu, K.S, Ha, J.H, Eo, Y. 登録日 2013-06-11 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition. J.Am.Chem.Soc., 135, 2013
5H82	HETEROYOHIMBINE SYNTHASE THAS2 FROM CATHARANTHUS ROSEUS - APO FORM 分子名称: ZINC ION, heteroyohimbine synthase THAS2 著者 Stavrinides, A, Tatsis, E.C, Caputi, L, Foureau, E, Stevenson, C.E.M, Lawson, D.M, Courdavault, V, O'Connor, S.E. 登録日 2015-12-23 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity. Nat Commun, 7, 2016
7PJ1	Solution structure of isolated Drosophila histone H2A-H2B heterodimer 分子名称: Histone H2A, Histone H2B 著者 van Ingen, H, Zhang, H. 登録日 2021-08-23 公開日 2021-12-08 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Mapping the electrostatic potential of the nucleosome acidic patch. Sci Rep, 11, 2021
7QP3	Pseudogymnoascus pannorum M36 protease without the propeptide 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wilkens, C, Qiu, J, Meyer, A.S, Morth, J.P. 登録日 2021-12-30 公開日 2023-01-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Phaeosphaeria nodorum M36 protease without the propeptide To Be Published
5H83	HETEROYOHIMBINE SYNTHASE HYS FROM CATHARANTHUS ROSEUS - APO FORM 分子名称: ZINC ION, heteroyohimbine synthase HYS 著者 Stavrinides, A, Tatsis, E.C, Caputi, L, Foureau, E, Stevenson, C.E.M, Lawson, D.M, Courdavault, V, O'Connor, S.E. 登録日 2015-12-23 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity. Nat Commun, 7, 2016
6HYI	Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine 分子名称: INOSINE, Protein kinase A regulatory subunit 著者 Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. 登録日 2018-10-22 公開日 2019-11-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.39944851 Å) 主引用文献 Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
2ZY9	Improved crystal structure of magnesium transporter MgtE 分子名称: MAGNESIUM ION, Mg2+ transporter MgtE 著者 Nureki, O, Ishitani, R, Hattori, M. 登録日 2009-01-19 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis Embo J., 28, 2009
3E9O	Crystal Structure of Yeast Prp8, Residues 1836-2092 分子名称: Pre-mRNA-splicing factor 8 著者 Pena, V, Rozov, A, Wahl, M.C. 登録日 2008-08-22 公開日 2008-10-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and function of an RNase H domain at the heart of the spliceosome. Embo J., 27, 2008
3E9P	Crystal Structure of Yeast Prp8, Residues 1827-2092 分子名称: Pre-mRNA-splicing factor 8 著者 Pena, V, Rozov, A, Wahl, M.C. 登録日 2008-08-22 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and function of an RNase H domain at the heart of the spliceosome. Embo J., 27, 2008
5HHL	Reverse transcriptase domain of group II intron maturase from Eubacterium rectale in P21 space group 分子名称: POTASSIUM ION, Retron-type reverse transcriptase 著者 Zhao, C, Pyle, A.M. 登録日 2016-01-11 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat.Struct.Mol.Biol., 23, 2016
5HHJ	Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... 著者 Zhao, C, Pyle, A.M. 登録日 2016-01-11 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat.Struct.Mol.Biol., 23, 2016
1LCL	CHARCOT-LEYDEN CRYSTAL PROTEIN 分子名称: LYSOPHOSPHOLIPASE 著者 Acharya, K.R, Leonidas, D.D. 登録日 1996-01-18 公開日 1997-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure, 3, 1995
8VH5	Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 dimer state 分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, ... 著者 Zhu, H, Sun, J. 登録日 2023-12-30 公開日 2024-10-09 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes. Nat Commun, 15, 2024
8VH4	Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 monomer state 分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION, ... 著者 Zhu, H, Sun, J. 登録日 2023-12-30 公開日 2024-10-09 最終更新日 2025-05-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 RAB12-LRRK2 complex suppresses primary ciliogenesis and regulates centrosome homeostasis in astrocytes. Nat Commun, 15, 2024
7SFF	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3852279B 分子名称: (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl}-2-[4-(trifluoromethyl)phenyl]acetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... 著者 Horton, J.R, Pathuri, S, Cheng, X. 登録日 2021-10-03 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
7SFC	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3735967A 分子名称: 1,2-ETHANEDIOL, DNA (12-MER), DNA (cytosine-5)-methyltransferase 1, ... 著者 Horton, J.R, Pathuri, S, Cheng, X. 登録日 2021-10-03 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
7SFD	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3543105A 分子名称: (2S)-2-({3,5-dicyano-4-ethyl-6-[4-(2-hydroxyethyl)-1,4-diazepan-1-yl]pyridin-2-yl}sulfanyl)-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... 著者 Horton, J.R, Pathuri, S, Cheng, X. 登録日 2021-10-03 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
7SFG	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Cofactor SAM 分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 1, DNA Strand 1, ... 著者 Horton, J.R, Pathuri, S, Cheng, X. 登録日 2021-10-03 公開日 2022-03-30 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
7SFE	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3830334A 分子名称: (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]amino}-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... 著者 Horton, J.R, Pathuri, S, Cheng, X. 登録日 2021-10-03 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
5IRF	Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P1 space group 分子名称: POTASSIUM ION, Retron-type reverse transcriptase 著者 Zhao, C, Pyle, A.M. 登録日 2016-03-13 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat.Struct.Mol.Biol., 23, 2016

<83848586878889909192939495969798>