PDB: 334 件ウェブページステータス検索Chemie searchBIRD

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6OY5	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min 分子名称: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2019-05-14 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6P1K	Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-05-20 公開日 2020-02-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
7KIF	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor 分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIM	Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor 分子名称: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIN	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter 分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7N4E	Escherichia coli sigma 70-dependent paused transcription elongation complex 分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Su, M, Ebright, R.H. 登録日 2021-06-04 公開日 2022-06-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural and mechanistic basis of sigma-dependent transcriptional pausing. Proc.Natl.Acad.Sci.USA, 119, 2022
7VWZ	Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-11-12 公開日 2022-06-08 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator. Nucleic Acids Res., 50, 2022
7VWY	Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y. 登録日 2021-11-12 公開日 2022-06-08 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.57 Å) 主引用文献 Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator. Nucleic Acids Res., 50, 2022
4XLQ	Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter 分子名称: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-13 公開日 2015-09-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (4.6 Å) 主引用文献 Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
4XSZ	Crystal structure of CBR 9393 bound to Escherichia coli RNA polymerase holoenzyme 分子名称: 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(piperazin-1-yl)ethyl]-2-(trifluoromethyl)aniline, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-22 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.683 Å) 主引用文献 CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proc.Natl.Acad.Sci.USA, 112, 2015
4XSX	Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-22 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.708 Å) 主引用文献 CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proc.Natl.Acad.Sci.USA, 112, 2015
7VF9	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2021-09-10 公開日 2022-07-27 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.04 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
4XLP	Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter 分子名称: DNA (25-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-13 公開日 2015-09-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
4XSY	Crystal structure of CBR 9379 bound to Escherichia coli RNA polymerase holoenzyme 分子名称: 3-{[(2,6-dichlorophenyl)carbamoyl]amino}-N-hydroxy-N'-phenyl-5-(trifluoromethyl)benzenecarboximidamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-22 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.007 Å) 主引用文献 CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proc.Natl.Acad.Sci.USA, 112, 2015
7W5W	Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y. 登録日 2021-11-30 公開日 2022-10-26 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5X	Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-11-30 公開日 2022-10-26 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
4YLO	E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuo, Y, Steitz, T.A. 登録日 2015-03-05 公開日 2015-04-22 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble. Mol.Cell, 58, 2015
4YFN	Escherichia coli RNA polymerase in complex with squaramide compound 14 (N-[3,4-dioxo-2-(4-{[4-(trifluoromethyl)benzyl]amino}piperidin-1-yl)cyclobut-1-en-1-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S. 登録日 2015-02-25 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.817 Å) 主引用文献 X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein. J.Med.Chem., 58, 2015
4ZH3	Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.082 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
4ZH4	Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18 分子名称: 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.993 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
7XL4	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2022-04-21 公開日 2022-07-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XL3	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2022-04-21 公開日 2022-07-27 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7X76	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X74	Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers. 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X75	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022

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