PDB: 659 件ウェブページステータス検索Chemie searchBIRD

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6IQS	Crystal structure of Prc with L245A and L340G mutations in complex with NlpI 分子名称: Lipoprotein NlpI, Tail-specific protease 著者 Chuech, C.K, Chang, C.I. 登録日 2018-11-08 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6IQR	Crystal structure of Prc with S452I and L252Y mutations 分子名称: Tail-specific protease 著者 Chueh, C.K, Chang, C.I. 登録日 2018-11-08 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6IQQ	Crystal structure of Prc with S452I and L252Y mutations in complex with NlpI 分子名称: CALCIUM ION, Lipoprotein NlpI, Tail-specific protease 著者 Chueh, C.K, Chang, C.I. 登録日 2018-11-08 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases. Mbio, 10, 2019
6HKS	Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide 分子名称: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3 著者 Genera, M, Haouz, A, Caillet-Saguy, C. 登録日 2018-09-07 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1944108 Å) 主引用文献 Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein. Sci Rep, 9, 2019
6GBE	Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain-PRK2 Peptide Complex 分子名称: Serine/threonine-protein kinase N2, Tyrosine-protein phosphatase non-receptor type 13 著者 Kock, G, Stoll, R. 登録日 2018-04-13 公開日 2018-12-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13. J. Mol. Biol., 430, 2018
6GBD	Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain 分子名称: PDZ3 著者 Kock, G, Stoll, R. 登録日 2018-04-13 公開日 2018-12-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13. J. Mol. Biol., 430, 2018
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. 分子名称: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 著者 Loew, C, Flayhan, A, Pieprzyk, J. 登録日 2017-11-15 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.503321 Å) 主引用文献 Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
6EW9	CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ... 著者 Vetter, I.R, Porfetye, A.T, Stege, P. 登録日 2017-11-03 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes. ACS Chem. Biol., 13, 2018
6ESP	Proteome-wide analysis of phospho-regulated PDZ domain interactions 分子名称: Protein scribble homolog 著者 Chi, N.C. 登録日 2017-10-24 公開日 2018-09-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Proteome-wide analysis of phospho-regulated PDZ domain interactions. Mol. Syst. Biol., 14, 2018
6EEY	Crystal structure of human Scribble PDZ4 R1110G Mutant 分子名称: Protein scribble homolog 著者 Janezic, E.M, Hsu, P, Hague, C. 登録日 2018-08-15 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.145 Å) 主引用文献 Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands. Sci Rep, 9, 2019
6BXG	1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. 分子名称: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ... 著者 Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-12-18 公開日 2018-01-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. To Be Published
6BJO	PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. 分子名称: (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6BJN	PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV 分子名称: PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6AR4	Crystal structure of PICK1 in complex with the small molecule inhibitor 1o 分子名称: N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein 著者 Marcotte, D. 登録日 2017-08-21 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Sci Rep, 8, 2018
6AK2	Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 分子名称: Syntenin-1, peptide inhibitor KSL-128018 著者 Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. 登録日 2018-08-29 公開日 2019-09-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.868 Å) 主引用文献 A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem., 64, 2021
5ZYS	Structure of Nephrin/MAGI1 complex 分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin 著者 Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. 登録日 2018-05-28 公開日 2019-01-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling. J. Am. Soc. Nephrol., 29, 2018
5ZDS	Crystal structure of the second PDZ domain of Frmpd2 分子名称: FERM and PDZ domain-containing 2 著者 Lu, X, Wang, X.F. 登録日 2018-02-24 公開日 2019-02-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem.Biophys.Res.Commun., 516, 2019
5XBF	Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 分子名称: ACETATE ION, D-MALATE, GLYCEROL, ... 著者 Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M. 登録日 2017-03-17 公開日 2017-05-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WQL	Structure of a PDZ-protease bound to a substrate-binding adaptor 分子名称: ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA, LEU-SER-ARG-SER, ... 著者 Su, M.Y, Chang, C.I. 登録日 2016-11-27 公開日 2017-11-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc Nat Commun, 8, 2017
5WOU	Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder 分子名称: 1,2-ETHANEDIOL, GUK-holder, isoform A, ... 著者 Caria, S, Kvansakul, M. 登録日 2017-08-03 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large. J. Biol. Chem., 293, 2018
5W72	Impact of IR active probes on PDZ3 and its ligand binding studied by NMR and X-ray crystallography 分子名称: Disks large homolog 4 著者 Lehner, F, Kudlinzki, D, Schwalbe, H, Silvers, R. 登録日 2017-06-19 公開日 2017-12-13 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
5VWK	Crystal structure of human Scribble PDZ1:Beta-PIX complex 分子名称: Beta-PIX, Protein scribble homolog, SULFATE ION 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-22 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5VWI	Crystal structure of human Scribble PDZ1:Beta-PIX complex 分子名称: Protein scribble homolog, beta-PIX 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-22 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5VWC	Crystal structure of human Scribble PDZ1 domain 分子名称: 1,2-ETHANEDIOL, Protein scribble homolog 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-21 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.911 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5V6T	The Plexin D1 intracellular region in complex with GIPC1 分子名称: PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION 著者 Shang, G, Zhang, X. 登録日 2017-03-17 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.189 Å) 主引用文献 Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017

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