PDB: 1551 件ウェブページステータス検索Chemie searchBIRD

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5CTT	Crystal structure of human SART3/TIP110 NLS-mouse importin alpha complex 分子名称: Importin subunit alpha-1, Squamous cell carcinoma antigen recognized by T-cells 3 著者 Park, J.K, Kim, E.E. 登録日 2015-07-24 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3 Nucleic Acids Res., 44, 2016
5CTR	Crystal structure of human SART3 HAT-C domain-human USP4 DUSP-UBL domain complex 分子名称: Squamous cell carcinoma antigen recognized by T-cells 3, Ubiquitin carboxyl-terminal hydrolase 4 著者 Park, J.K, Kim, E.E. 登録日 2015-07-24 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.012 Å) 主引用文献 Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3 Nucleic Acids Res., 44, 2016
5CTQ	Crystal structure of human SART3/TIP110 half-a TPR (HAT) domain 分子名称: Squamous cell carcinoma antigen recognized by T-cells 3 著者 Park, J.K, Kim, E.E. 登録日 2015-07-24 公開日 2016-04-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3 Nucleic Acids Res., 44, 2016
4RZ9	Pre-mRNA-splicing factor 38A AS 1-179 分子名称: Pre-mRNA-splicing factor 38A 著者 Schuetze, T, Weber, G, Wahl, M.C. 登録日 2014-12-19 公開日 2015-12-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
4RZA	Pre-mRNA-splicing factor 38A AS 1-205 分子名称: Pre-mRNA-splicing factor 38A 著者 Schuetze, T, Ulrich, A, Wahl, M.C. 登録日 2014-12-19 公開日 2015-12-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
7ZNL	Structure of the human TREX core THO-UAP56 complex 分子名称: Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... 著者 Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. 登録日 2022-04-21 公開日 2023-05-17 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
7APK	Structure of the human THO - UAP56 complex 分子名称: Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... 著者 Hohmann, U, Puehringer, T, Plaschka, C. 登録日 2020-10-17 公開日 2020-12-16 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
5LSB	Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. 分子名称: Cold sensitive U2 snRNA suppressor 1, Protein HSH49 著者 van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. 登録日 2016-08-24 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain. RNA, 23, 2017
1PQN	dominant negative human hDim1 (hDim1 1-128) 分子名称: Spliceosomal U5 snRNP-specific 15 kDa protein 著者 Zhang, Y.Z, Cheng, H, Gould, K.L, Golemis, E.A, Roder, H. 登録日 2003-06-18 公開日 2003-08-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure, stability and function of hDim1 investigated by NMR, circular dichroism and mutational analysis Biochemistry, 42, 2003
5M8C	Spliceosome component 分子名称: Pre-mRNA-processing factor 19 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
5M88	Spliceosome component 分子名称: Core 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
3E66	Crystal structure of the beta-finger domain of yeast Prp8 分子名称: PRP8 著者 Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R. 登録日 2008-08-14 公開日 2008-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. Proc.Natl.Acad.Sci.Usa, 105, 2008
4V98	The 8S snRNP Assembly Intermediate 分子名称: CG10419, Icln, LD23602p, ... 著者 Grimm, C, Pelz, J.P, Schindelin, H, Diederichs, K, Kuper, J, Kisker, C. 登録日 2012-05-15 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis of Assembly Chaperone- Mediated snRNP Formation. Mol.Cell, 49, 2013
6PPP	Structure of S. pombe Lsm2-8 with processed U6 snRNA 分子名称: Mimic of processed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
6Y5Q	human 17S U2 snRNP 分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... 著者 Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. 登録日 2020-02-25 公開日 2020-06-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
6Y53	human 17S U2 snRNP low resolution part 分子名称: HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... 著者 Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. 登録日 2020-02-24 公開日 2020-06-17 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
8HK1	The cryo-EM structure of human pre-17S U2 snRNP 分子名称: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... 著者 Zhang, X, Zhan, X, Shi, Y. 登録日 2022-11-24 公開日 2023-03-08 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
3PGW	Crystal structure of human U1 snRNP 分子名称: DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ... 著者 Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C. 登録日 2010-11-02 公開日 2010-12-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Functional organization of the Sm core in the crystal structure of human U1 snRNP. Embo J., 29, 2010
3JCR	3D structure determination of the human*U4/U6.U5* tri-snRNP complex 分子名称: LSm2, LSm3, LSm4, ... 著者 Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. 登録日 2016-01-21 公開日 2016-03-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
6Y50	5'domain of human 17S U2 snRNP 分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... 著者 Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. 登録日 2020-02-24 公開日 2020-07-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
4PYU	The conserved ubiquitin-like protein hub1 plays a critical role in splicing in human cells 分子名称: U4/U6.U5 tri-snRNP-associated protein 1, Ubiquitin-like protein 5 著者 Ammon, T, Mishra, S.K, Kowalska, K, Popowicz, G.M, Holak, T.A, Jentsch, S. 登録日 2014-03-28 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. J Mol Cell Biol, 6, 2014
7ONB	Structure of the U2 5' module of the A3'-SSA complex 分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-25 公開日 2021-08-04 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
8Q91	Structure of the human 20S U5 snRNP core 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-08-19 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
8RC0	Structure of the human 20S U5 snRNP 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Schneider, S, Galej, W.P. 登録日 2023-12-05 公開日 2024-03-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the human 20S U5 snRNP. Nat.Struct.Mol.Biol., 31, 2024
5XJR	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E/G from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Yi, H, Zhang, R. 登録日 2017-05-04 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly. Nucleic Acids Res., 2019

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