8EV6
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs | 分子名称: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Seely, S.M, Gagnon, M.G. | 登録日 | 2022-10-19 | 公開日 | 2023-08-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.946 Å) | 主引用文献 | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EKB
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, deacylated P-site tRNAmet, and thermorubin at 2.70A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Paranjpe, M.N, Polikanov, Y.S. | 登録日 | 2022-09-20 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin. Nucleic Acids Res., 51, 2023
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8PKH
| Borrelia bacteriophage BB1 procapsid, fivefold-symmetrized outer shell | 分子名称: | Decorator protein P03, Decorator protein P04, Decorator protein P05, ... | 著者 | Rumnieks, J, Fuzik, T, Tars, K. | 登録日 | 2023-06-26 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of the Borrelia Bacteriophage phi BB1 Procapsid. J.Mol.Biol., 435, 2023
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8P60
| Spraguea lophii ribosome dimer | 分子名称: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | 著者 | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | 登録日 | 2023-05-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (14.3 Å) | 主引用文献 | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state. Nat Microbiol, 8, 2023
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8QAV
| Medicago truncatula HISN5 (IGPD) in complex with MN and IG2 | 分子名称: | (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION | 著者 | Witek, W, Ruszkowski, M. | 登録日 | 2023-08-23 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
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7XNV
| Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry) | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | 著者 | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | 登録日 | 2022-04-29 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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8EZ4
| Plasmodium falciparum M17 in complex with inhibitor 9aa | 分子名称: | CARBONATE ION, M17 leucyl aminopeptidase, N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-N~2~-phenylglycinamide, ... | 著者 | Calic, P.P.S, McGowan, S, Webb, C.T. | 登録日 | 2022-10-31 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1'-region optimisation. Eur.J.Med.Chem., 248, 2022
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7XNH
| Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | 著者 | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | 登録日 | 2022-04-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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8R3V
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7XKT
| Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | 登録日 | 2022-04-20 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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8EM7
| Cryo-EM structure of LRP2 at pH 5.2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-27 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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8EM4
| Cryo-EM structure of LRP2 at pH 7.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-26 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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8EV7
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Seely, S.M, Gagnon, M.G. | 登録日 | 2022-10-19 | 公開日 | 2023-08-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EVP
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Zhao, Y, Rai, J, Li, H. | 登録日 | 2022-10-20 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EUB
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Zhao, Y, Rai, J, Li, H. | 登録日 | 2022-10-18 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EVR
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II | 分子名称: | (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ... | 著者 | Zhao, Y, Rai, J, Li, H. | 登録日 | 2022-10-20 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EVQ
| Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Zhao, Y, Rai, J, Li, H. | 登録日 | 2022-10-20 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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7XNX
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8FKX
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8FKP
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8FKW
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8FL9
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8QV3
| Structure of the y-Tubulin Small Complex (yTuSC) as part of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, Spindle pole body component 110, ... | 著者 | Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D. | 登録日 | 2023-10-17 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | Structure of the native gamma-tubulin ring complex capping spindle microtubules. Nat.Struct.Mol.Biol., 2024
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8FKY
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8FKV
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