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2CGH
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crystal structure of biotin ligase from Mycobacterium tuberculosis
分子名称: BIOTIN LIGASE
著者Ma, Q, Wilmanns, M.
登録日2006-03-06
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Active Site Conformational Changes Upon Reaction Intermediate Biotinyl-5'-AMP Binding in Biotin Protein Ligase from Mycobacterium Tuberculosis.
Protein Sci., 23, 2014
6X0O
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Single-Particle Cryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbB
著者Tan, Y.Z, Rodrigues, J, Keener, J.E, Zheng, R.B, Brunton, R, Kloss, B, Giacometti, S.I, Rosario, A.L, Zhang, L, Niederweis, M, Clarke, O.B, Lowary, T.L, Marty, M.T, Archer, M, Potter, C.S, Carragher, B, Mancia, F.
登録日2020-05-17
公開日2020-06-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis.
Nat Commun, 11, 2020
4NQW
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Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA
分子名称: Anti-sigma-K factor RskA, CADMIUM ION, ECF RNA polymerase sigma factor SigK
著者Shukla, J.K, Gopal, B.
登録日2013-11-25
公開日2014-01-22
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex
Acta Crystallogr.,Sect.D, 70, 2014
6YCA
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Crystal structure of Eis1 from Mycobacterium abscessus
分子名称: ACETYL COENZYME *A, SULFATE ION, Uncharacterized N-acetyltransferase D2E76_00625
著者Blaise, M, Ung, K.L.
登録日2020-03-18
公開日2020-09-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural analysis of the N-acetyltransferase Eis1 from Mycobacterium abscessus reveals the molecular determinants of its incapacity to modify aminoglycosides.
Proteins, 89, 2021
4RLU
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BU of 4rlu by Molmil
Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis complexed with 2',4,4'-trihydroxychalcone
分子名称: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 2',4,4'-TRIHYDROXYCHALCONE, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-18
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
3HX9
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BU of 3hx9 by Molmil
Structure of heme-degrader, MhuD (Rv3592), from Mycobacterium tuberculosis with two hemes bound in its active site
分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Protein Rv3592
著者Chim, N, Nguyen, T.Q, Iniguez, A, Goulding, C.W.
登録日2009-06-19
公開日2009-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis
J.Mol.Biol., 395, 2009
7DOJ
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BU of 7doj by Molmil
Solution structure of TGS domain of the Mycobacterium tuberculosis Rel protein
分子名称: GTP pyrophosphokinase
著者Joon, S, Singal, B, Grueber, G.
登録日2020-12-14
公開日2021-12-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Atomic structure of the regulatory TGS domain of Rel protein from Mycobacterium tuberculosis and its interaction with deacylated tRNA.
Febs Lett., 595, 2021
2Y0P
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Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase in complex with the enamine-ThDP intermediate and acetyl-CoA
分子名称: (4E)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-2(3H)-ylidene}-4-hydroxybutanoic acid, 2-OXOGLUTARATE DECARBOXYLASE, ACETYL COENZYME *A, ...
著者Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M.
登録日2010-12-07
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism.
Chem.Biol., 18, 2011
4RLJ
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Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis
分子名称: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-17
公開日2015-10-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
4OL4
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Crystal structure of secreted proline rich antigen MTC28 (Rv0040c) from Mycobacterium tuberculosis
分子名称: Proline-rich 28 kDa antigen
著者Kundu, P, Biswas, R, Mukherjee, S, Reinhard, L, Mueller-dieckmann, J, Weiss, M.S, Das, A.K.
登録日2014-01-23
公開日2015-01-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based Epitope Mapping of Mycobacterium tuberculosis Secretary Antigen MTC28
J.Biol.Chem., 291, 2016
3CE6
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BU of 3ce6 by Molmil
Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and adenosine
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Reddy, M.C.M, Gokulan, K, Shetty, N.D, Owen, J.L, Ioerger, T.R, Sacchettini, J.C.
登録日2008-02-28
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.
Protein Sci., 17, 2008
1MRU
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BU of 1mru by Molmil
Intracellular Ser/Thr protein kinase domain of Mycobacterium tuberculosis PknB.
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Probable serine/threonine-protein kinase pknB
著者Young, T.A, Delagoutte, B, Endrizzi, J.A, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2002-09-18
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases.
Nat.Struct.Biol., 10, 2003
2QZ8
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BU of 2qz8 by Molmil
Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA)
分子名称: Probable transcriptional regulatory protein
著者Manchi, C.M.R, Gokulan, K, Ioerger, T, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2007-08-16
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response.
Protein Sci., 17, 2008
4RLT
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BU of 4rlt by Molmil
Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis complexed with Fisetin
分子名称: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,7,3',4'-TETRAHYDROXYFLAVONE, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-18
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
2JFR
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BU of 2jfr by Molmil
Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with phosphate at 0.83 A resolution
分子名称: CHLORIDE ION, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M.
登録日2007-02-04
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (0.83 Å)
主引用文献Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
Structure, 15, 2007
2JFT
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BU of 2jft by Molmil
Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate
分子名称: MAGNESIUM ION, MANGANESE (II) ION, SER-THR PHOSPHATASE MSPP, ...
著者Bellinzoni, M, Wehenkel, A, Shepard, W, Alzari, P.M.
登録日2007-02-04
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Insights Into the Mechanism of Ppm Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
Structure, 15, 2007
2LQO
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Mrx1 reduced
分子名称: Putative glutaredoxin Rv3198.1/MT3292
著者Buts, L, Van Laer, K, Messens, J.
登録日2012-03-10
公開日2012-10-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria.
Mol.Microbiol., 86, 2012
2LKY
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BU of 2lky by Molmil
Solution structure of MSMEG_1053, the second DUF3349 annotated protein in the genome of Mycobacterium smegmatis, Seattle Structural Genomics Center for Infectious Disease target MysmA.17112.b
分子名称: Uncharacterized protein
著者Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-10-22
公開日2011-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the Mycobacteria DUF3349 superfamily.
Protein Sci., 29, 2020
2LQQ
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Oxidized Mrx1
分子名称: Putative glutaredoxin Rv3198.1/MT3292
著者Buts, L, Van Laer, K, Messens, J.
登録日2012-03-11
公開日2012-10-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria.
Mol.Microbiol., 86, 2012
4RLW
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BU of 4rlw by Molmil
Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis complexed with Butein
分子名称: (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one, (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-18
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
2KGS
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BU of 2kgs by Molmil
Solution structure of the amino-terminal domain of OmpATb, a pore forming protein from Mycobacterium tuberculosis
分子名称: Uncharacterized protein Rv0899/MT0922
著者Yang, Y, Auguin, D, Delbecq, S, Dumas, E, Molle, V, Saint, N.
登録日2009-03-18
公開日2010-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the Mycobacterium tuberculosis OmpATb protein: A model of an oligomeric channel in the mycobacterial cell wall
Proteins, 79, 2011
2M0N
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BU of 2m0n by Molmil
Solution structure of a DUF3349 annotated protein from Mycobacterium abscessus, MAB_3403c. Seattle Structural Genomics Center for Infectious Disease target MyabA.17112.a.A2
分子名称: Putative uncharacterized protein
著者Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-10-30
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural diversity in the Mycobacteria DUF3349 superfamily.
Protein Sci., 29, 2020
1XDI
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BU of 1xdi by Molmil
Crystal structure of LpdA (Rv3303c) from Mycobacterium tuberculosis
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Rv3303c-lpdA
著者Argyrou, A, Vetting, M.W, Blanchard, J.S.
登録日2004-09-06
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Characterization of a New Member of the Flavoprotein Disulfide Reductase Family of Enzymes from Mycobacterium tuberculosis
J.Biol.Chem., 279, 2004
3E4Y
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Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. I2(1)2(1)2(1) crystal form
分子名称: GLYCEROL, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Pakhomova, S, Newcomer, M.E.
登録日2008-08-12
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
5E0Z
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Crystal Structure of PASTA Domains 3 and 4 of Mycobacterium tuberculosis Protein Kinase B
分子名称: Serine/threonine-protein kinase PknB
著者Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC)
登録日2015-09-29
公開日2016-09-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016

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