5XXV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xxv by Molmil](/molmil-images/mine/5xxv) | GDP-microtubule complexed with KIF5C in AMPPNP state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Morikawa, M, Shigematsu, H, Nitta, R, Hirokawa, N. | 登録日 | 2017-07-05 | 公開日 | 2018-10-10 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (6.46 Å) | 主引用文献 | Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport J. Cell Biol., 217, 2018
|
|
5YAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yac by Molmil](/molmil-images/mine/5yac) | Crystal structure of WT Trm5b from Pyrococcus abyssi | 分子名称: | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 著者 | Xie, W, Wu, J. | 登録日 | 2017-08-31 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The crystal structure of the Pyrococcus abyssi mono-functional methyltransferase PaTrm5b Biochem. Biophys. Res. Commun., 493, 2017
|
|
5YC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yc9 by Molmil](/molmil-images/mine/5yc9) | |
5Y2Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y2z by Molmil](/molmil-images/mine/5y2z) | Crystal structure of human LGI1 EPTP-ADAM22 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yamagata, A, Fukai, S. | 登録日 | 2017-07-27 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
|
|
5Y8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y8z by Molmil](/molmil-images/mine/5y8z) | Crystal Structure Analysis of the BRD4 | 分子名称: | 1,2-ETHANEDIOL, 5-bromanyl-N-(3,6-dimethyl-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide, Bromodomain-containing protein 4, ... | 著者 | Xu, Y, Zhang, Y, Song, M, Wang, C. | 登録日 | 2017-08-22 | 公開日 | 2018-06-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) J. Med. Chem., 61, 2018
|
|
5YK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yk4 by Molmil](/molmil-images/mine/5yk4) | Mismatch Repair Protein | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS | 著者 | Nirwal, S, Nair, D.T. | 登録日 | 2017-10-12 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Mechanism of formation of a toroid around DNA by the mismatch sensor protein. Nucleic Acids Res., 46, 2018
|
|
5YM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ym3 by Molmil](/molmil-images/mine/5ym3) | CYP76AH1-4pi from salvia miltiorrhiza | 分子名称: | 4-PHENYL-1H-IMIDAZOLE, Ferruginol synthase, MANGANESE (II) ION, ... | 著者 | Chang, Z. | 登録日 | 2017-10-20 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Crystal structure of CYP76AH1 in 4-PI-bound state from Salvia miltiorrhiza. Biochem.Biophys.Res.Commun., 511, 2019
|
|
5YP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yp6 by Molmil](/molmil-images/mine/5yp6) | RORgamma (263-509) complexed with SRC2 and Compound 6 | 分子名称: | N-[3'-cyano-4'-(2-methylpropyl)-2-(trifluoromethyl)biphenyl-4-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, SRC2 | 著者 | Gao, M, Cai, W. | 登録日 | 2017-11-01 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | From ROR gamma t Agonist to Two Types of ROR gamma t Inverse Agonists ACS Med Chem Lett, 9, 2018
|
|
5YFC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yfc by Molmil](/molmil-images/mine/5yfc) | Crystal structure of a new DPP III family member | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Dipeptidyl peptidase 3, ... | 著者 | Xu, T, Liu, J. | 登録日 | 2017-09-20 | 公開日 | 2018-01-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structures of Aflatoxin-oxidase from Armillariella tabescens reveal a dual activity enzyme. Biochem. Biophys. Res. Commun., 494, 2017
|
|
5YG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yg3 by Molmil](/molmil-images/mine/5yg3) | Plasmodium vivax SHMT bound with PLP-glycine and S-GS834 | 分子名称: | (3~{S})-6'-azanyl-7-fluoranyl-2,2,3'-trimethyl-5-pyridin-4-yl-spiro[1~{H}-indene-3,4'-2~{H}-pyrano[2,3-c]pyrazole]-5'-carbonitrile, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G, Diederich, F. | 登録日 | 2017-09-22 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold ChemMedChem, 13, 2018
|
|
5Y5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y5k by Molmil](/molmil-images/mine/5y5k) | Time-resolved SFX structure of cytochrome P450nor : 20 ms after photo-irradiation of caged NO in the absence of NADH (NO-bound state), light data | 分子名称: | NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Tosha, T, Nomura, T, Nishida, T, Saeki, N, Okubayashi, K, Yamagiwa, R, Sugahara, M, Nakane, T, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Mizohata, E, Yamashita, A, Kanematsu, Y, Takano, Y, Nango, E, Tanaka, R, Nureki, O, Ikemoto, Y, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Iwata, S, Sugimoto, H, Shiro, Y, Kubo, M. | 登録日 | 2017-08-09 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
|
|
5Y69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y69 by Molmil](/molmil-images/mine/5y69) | Crystal structure of the L52M mutant of AcrIIA1 | 分子名称: | chain A | 著者 | Ka, D, An, S.Y, Suh, J.Y, Bae, E. | 登録日 | 2017-08-11 | 公開日 | 2017-11-29 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of an anti-CRISPR protein, AcrIIA1. Nucleic Acids Res., 46, 2018
|
|
5YJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yjj by Molmil](/molmil-images/mine/5yjj) | Crystal structure of PNPase from Staphylococcus epidermidis | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Polyribonucleotide nucleotidyltransferase | 著者 | Raj, R, Gopal, B. | 登録日 | 2017-10-10 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Characterization of Staphylococcus epidermidis Polynucleotide phosphorylase and its interactions with ribonucleases RNase J1 and RNase J2. Biochem. Biophys. Res. Commun., 495, 2018
|
|
5YBL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ybl by Molmil](/molmil-images/mine/5ybl) | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AusE | 分子名称: | 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Multifunctional dioxygenase ausE | 著者 | Nakashima, Y, Senda, M. | 登録日 | 2017-09-05 | 公開日 | 2018-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis. Nat Commun, 9, 2018
|
|
5YEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yep by Molmil](/molmil-images/mine/5yep) | Crystal structure of SO_3166-SO_3165 from Shewanella oneidensis | 分子名称: | Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | 著者 | Jia, X, Gao, Z.Q, Zhang, H, Dong, Y.H. | 登録日 | 2017-09-19 | 公開日 | 2018-03-28 | 最終更新日 | 2019-04-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-function analyses reveal the molecular architecture and neutralization mechanism of a bacterial HEPN-MNT toxin-antitoxin system. J. Biol. Chem., 293, 2018
|
|
5YFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yfd by Molmil](/molmil-images/mine/5yfd) | Crystal structure of a new DPP III family member | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, Dipeptidyl peptidase 3, ... | 著者 | Xu, T, Liu, J. | 登録日 | 2017-09-20 | 公開日 | 2018-01-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structures of Aflatoxin-oxidase from Armillariella tabescens reveal a dual activity enzyme. Biochem. Biophys. Res. Commun., 494, 2017
|
|
5YI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yi5 by Molmil](/molmil-images/mine/5yi5) | human ferritin mutant - E-helix deletion | 分子名称: | Ferritin heavy chain | 著者 | Lee, S.G, Yoon, H.R, Ahn, B.J, Jeong, H, Hyun, J, Jung, Y, Kim, H. | 登録日 | 2017-10-02 | 公開日 | 2018-02-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
5Y7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y7r by Molmil](/molmil-images/mine/5y7r) | Quaternary complex of AsqJ-Fe3+-2OG-cyclopeptin | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | 著者 | Liao, H.J, Lin, T.S. | 登録日 | 2017-08-17 | 公開日 | 2018-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation. Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
5YT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yt8 by Molmil](/molmil-images/mine/5yt8) | |
5Y5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y5g by Molmil](/molmil-images/mine/5y5g) | Structure of cytochrome P450nor in NO-bound state: damaged by high-dose (5.7 MGy) X-ray | 分子名称: | GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ... | 著者 | Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M. | 登録日 | 2017-08-09 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
|
|
5Y9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y9o by Molmil](/molmil-images/mine/5y9o) | |
5YBI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ybi by Molmil](/molmil-images/mine/5ybi) | Structure of the bacterial pathogens ATPase with substrate AMPPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ATP synthase SpaL/MxiB, ... | 著者 | Mu, Z.X, Gao, X.P, Cui, S. | 登録日 | 2017-09-05 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.268 Å) | 主引用文献 | Structural Insight Into Conformational Changes Induced by ATP Binding in a Type III Secretion-Associated ATPase FromShigella flexneri. Front Microbiol, 9, 2018
|
|
5YFZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yfz by Molmil](/molmil-images/mine/5yfz) | Plasmodium vivax SHMT bound with PLP-glycine and S-GS626 | 分子名称: | 2-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]piperidin-4-yl]ethanoic acid, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G, Diederich, F. | 登録日 | 2017-09-22 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold ChemMedChem, 13, 2018
|
|
5YH0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yh0 by Molmil](/molmil-images/mine/5yh0) | |
5YKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yke by Molmil](/molmil-images/mine/5yke) | |