8JKD
 
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1W93
 | | Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae | | 分子名称: | ACETYL-COENZYME A CARBOXYLASE | | 著者 | Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. | | 登録日 | 2004-10-05 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
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1W2B
 | | Trigger Factor ribosome binding domain in complex with 50S | | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ... | | 著者 | Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N. | | 登録日 | 2004-07-01 | | 公開日 | 2004-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
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4UVB
 | | LSD1(KDM1A)-CoREST in complex with 1-Methyl-Tranylcypromine (1S,2R) | | 分子名称: | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,7aS)-1-amino-1,10,11-trimethyl-4,6-dioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | | 著者 | Vianello, P, Botrugno, O, Cappa, A, Ciossani, G, Dessanti, P, Mai, A, Mattevi, A, Meroni, G, Minucci, S, Thaler, F, Tortorici, M, Trifiro, P, Valente, S, Villa, M, Varasi, M, Mercurio, C. | | 登録日 | 2014-08-05 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A.
Eur.J.Med.Chem., 86C, 2014
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1VQN
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1VY7
 | | Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site. | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Polikanov, Y.S, Steitz, T.A, Innis, C.A. | | 登録日 | 2014-05-13 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
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1VQ4
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1VKJ
 | | Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, SULFATE ION, heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | | 著者 | Thorp, S, Lee, K.A, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C. | | 登録日 | 2004-05-25 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1
J.Biol.Chem., 279, 2004
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4UVC
 | | LSD1(KDM1A)-CoREST in complex with 1-Phenyl-Tranylcypromine | | 分子名称: | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-[5-[(1S)-1-azanyl-1,3-diphenyl-propyl]-7,8-dimethyl-2,4-bis(oxidanylidene)-4aH-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | | 著者 | Vianello, P, Botrugno, O, Cappa, A, Ciossani, G, Dessanti, P, Mai, A, Mattevi, A, Meroni, G, Minucci, S, Thaler, F, Tortorici, M, Trifiro, P, Valente, S, Villa, M, Varasi, M, Mercurio, C. | | 登録日 | 2014-08-05 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A.
Eur.J.Med.Chem., 86C, 2014
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1VQO
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6ZR2
 | | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | 登録日 | 2020-07-10 | | 公開日 | 2020-10-21 | | 最終更新日 | 2020-10-28 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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1W5D
 | | Crystal structure of PBP4a from Bacillus subtilis | | 分子名称: | CALCIUM ION, PENICILLIN-BINDING PROTEIN | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-08-06 | | 公開日 | 2005-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Bacillus Subtilis Penicillin-Binding Protein 4A, and its Complex with a Peptidoglycan Mimetic Peptide.
J.Mol.Biol., 371, 2007
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1W14
 | | UROKINASE TYPE PLASMINOGEN ACTIVATOR | | 分子名称: | N-[(2-PHENYLETHYL)SULFONYL]-D-SERYL-N-[(1S)-4-[(DIAMINOMETHYLENE)AMINO]-1-(HYDROXYMETHYL)BUTYL]-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Jacob, U. | | 登録日 | 2004-06-15 | | 公開日 | 2008-05-20 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors.
J.Mol.Biol., 328, 2003
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1VJA
 | | Urokinase Plasminogen Activator B-Chain-JT463 Complex | | 分子名称: | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[(Z)-AMINO(IMINO)METHYL]BENZYL}SERINAMIDE, SULFATE ION, plasminogen activator, ... | | 著者 | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | | 登録日 | 2004-02-03 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
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1VS3
 | | Crystal Structure of the tRNA Pseudouridine Synthase TruA From Thermus thermophilus HB8 | | 分子名称: | tRNA pseudouridine synthase A | | 著者 | Dong, X, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-06-28 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.
Rna Biol., 3, 2006
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1VQ6
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1VQ7
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1VQ5
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1VJ9
 | | Urokinase Plasminogen Activator B-Chain-JT464 Complex | | 分子名称: | N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... | | 著者 | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | | 登録日 | 2004-02-03 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
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1VQP
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1W10
 | | Urokinase type plasminogen activator | | 分子名称: | N-(ISOBUTOXYCARBONYL)-D-SERYL-N-((1S)-4-{[AMINO(IMINO)METHYL]AMINO}-1-FORMYLBUTYL)-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Jacob, U. | | 登録日 | 2004-06-15 | | 公開日 | 2008-05-20 | | 最終更新日 | 2019-09-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors.
J.Mol.Biol., 328, 2003
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1VPO
 | | Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone | | 分子名称: | TESTOSTERONE, anti-testosterone (heavy chain), anti-testosterone (light chain) | | 著者 | Valjakka, J.M, Hemminki, A, Niemi, S, Soderlund, H, Takkinen, K, Rouvinen, J. | | 登録日 | 2004-11-15 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone
Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM
SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS
J.Biol.Chem., 277, 2002
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1W11
 | | UROKINASE TYPE PLASMINOGEN ACTIVATOR | | 分子名称: | N-(BENZYLSULFONYL)-D-SERYL-N-{4-[AMINO(IMINO)METHYL]BENZYL}-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Jacob, U. | | 登録日 | 2004-06-15 | | 公開日 | 2008-05-20 | | 最終更新日 | 2019-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors.
J.Mol.Biol., 328, 2003
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1W96
 | | Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A | | 分子名称: | ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A | | 著者 | Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. | | 登録日 | 2004-10-06 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
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1W13
 | | UROKINASE TYPE PLASMINOGEN ACTIVATOR | | 分子名称: | N-(BENZYLSULFONYL)-D-SERYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BENZYL)-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Jacob, U. | | 登録日 | 2004-06-15 | | 公開日 | 2008-05-20 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors.
J.Mol.Biol., 328, 2003
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