PDB: 5689 件ウェブページステータス検索Chemie searchBIRD

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1U1J	A. thaliana cobalamine independent methionine synthase 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, ... 著者 Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. 登録日 2004-07-15 公開日 2004-09-14 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
2DG3	Wildtype FK506-binding protein complexed with Rapamycin 分子名称: FK506-binding protein 1A, GLYCEROL, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Buckle, A.M. 登録日 2006-03-08 公開日 2006-04-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Energetic and structural analysis of the role of tryptophan 59 in FKBP12 Biochemistry, 42, 2003
2DGB	Structure of Thermus thermophilus PurS in the P21 Form 分子名称: hypothetical protein PurS 著者 Yanai, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-10 公開日 2006-09-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Thermus thermophilus PurS, One of the Subunits of Formylglycinamide Ribonucleotide Amidotransferase in the Purine Biosynthetic Pathway To be published
6F0A	Crystal structure of human indoleamine 2,3-dioxygenase bound to a triazole inhibitor and alanine molecule. 分子名称: ALANINE, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Swan, M.K, Latchem, M. 登録日 2017-11-17 公開日 2017-12-27 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 New 4-Amino-1,2,3-Triazole Inhibitors of Indoleamine 2,3-Dioxygenase Form a Long-Lived Complex with the Enzyme and Display Exquisite Cellular Potency. Chembiochem, 19, 2018
1U11	PurE (N5-carboxyaminoimidazole Ribonucleotide Mutase) from the acidophile Acetobacter aceti 分子名称: CITRIC ACID, PurE (N5-carboxyaminoimidazole Ribonucleotide Mutase) 著者 Settembre, E.C, Chittuluru, J.R, Mill, C.P, Kappock, T.J, Ealick, S.E. 登録日 2004-07-14 公開日 2004-09-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Acidophilic adaptations in the structure of Acetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE). Acta Crystallogr.,Sect.D, 60, 2004
1U1U	A. thaliana cobalamine independent methionine synthase 分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION 著者 Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. 登録日 2004-07-16 公開日 2004-09-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
2DWC	Crystal structure of Probable phosphoribosylglycinamide formyl transferase from Pyrococcus horikoshii OT3 complexed with ADP 分子名称: 433aa long hypothetical phosphoribosylglycinamide formyl transferase, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION 著者 Yoshikawa, S, Arai, R, Kamo-Uchikubo, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-08-10 公開日 2007-02-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Probable phosphoribosylglycinamide formyl transferase from Pyrococcus horikoshii OT3 complexed with ADP To be Published
6ZWZ	Resting state structure of the OMPD-domain of human UMPS variant (K314AcK) at 1.2 Angstroms resolution 分子名称: SULFATE ION, Uridine 5'-monophosphate synthase 著者 Tittmann, K, Rindfleisch, S, Krull, M. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
6ZX1	OMPD-domain of human UMPS in complex with 6-Aza-UMP at 1.0 Angstroms resolution 分子名称: 6-AZA URIDINE 5'-MONOPHOSPHATE, PROLINE, SULFATE ION, ... 著者 Tittmann, K, Rindfleisch, S, Krull, M. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
6ZX0	OMPD-domain of human UMPS in complex with the substrate OMP at 1.25 Angstroms resolution 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ... 著者 Tittmann, K, Rindfleisch, S, Krull, M. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
6ZWY	OMPD-domain of human UMPS in complex with UMP at 1.0 Angstroms resolution 分子名称: GLYCEROL, PROLINE, URIDINE-5'-MONOPHOSPHATE, ... 著者 Tittmann, K, Rindfleisch, S. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
6ZX3	OMPD-domain of human UMPS in complex with 6-thiocarboxamido-UMP at 1.15 Angstroms resolution 分子名称: GLYCEROL, PROLINE, SULFATE ION, ... 著者 Tittmann, K, Rindfleisch, S, Schimdt, T. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
6ZX2	OMPD-domain of human UMPS in complex with 6-carboxamido-UMP at 1.2 Angstroms resolution 分子名称: PROLINE, SULFATE ION, Uridine 5'-monophosphate synthase, ... 著者 Tittmann, K, Rindfleisch, S, Schimdt, T. 登録日 2020-07-29 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
7ODX	Cyanophage S-2L Succinoaminodeoxyadenylate synthetase (PurZ) bound to dGMP and dATP as an energy donor 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Succinoaminodeoxyadenylate synthetase (PurZ) 著者 Czernecki, D, Delarue, M. 登録日 2021-04-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.69617081 Å) 主引用文献 Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA. Nat Commun, 12, 2021
3AJX	Crystal Structure of 3-Hexulose-6-Phosphate Synthase 分子名称: 3-hexulose-6-phosphate synthase, CHLORIDE ION, MAGNESIUM ION, ... 著者 Kita, A, Orita, I, Yurimoto, H, Kato, N, Sakai, Y, Miki, K. 登録日 2010-06-24 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of 3-hexulose-6-phosphate synthase, a member of the orotidine 5'-monophosphate decarboxylase suprafamily Proteins, 78, 2010
3AV3	Crystal structure of glycinamide ribonucleotide transformylase 1 from Geobacillus kaustophilus 分子名称: MAGNESIUM ION, Phosphoribosylglycinamide formyltransferase 著者 Kanagawa, M, Baba, S, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-02-18 公開日 2012-03-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures and reaction mechanisms of the two related enzymes, PurN and PurU. J.Biochem., 154, 2013
5EA9	Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with Neq0130 分子名称: 1,2-ETHANEDIOL, 5-[(E)-3-thiophen-2-ylprop-2-enylidene]-1,3-diazinane-2,4,6-trione, COBALT HEXAMMINE(III), ... 著者 Rocha, J.R, Inaoka, D.K, Cheleski, J, Shiba, T, Harada, S, Montanari, C.A, Kita, K. 登録日 2015-10-15 公開日 2016-10-19 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Exploring Trypanosoma cruzi Dihydroorotate Dehydrogenase Active Site Plasticity for the Discovery of Potent and Selective Inhibitors with Trypanocidal Activity To be Published
5E93	Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with Neq0071 分子名称: 1,2-ETHANEDIOL, 5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, CACODYLATE ION, ... 著者 Rocha, J.R, Inaoka, D.K, Cheleski, J, Shiba, T, Harada, S, Montanari, C.A, Kita, K. 登録日 2015-10-14 公開日 2016-10-19 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Exploring Trypanosoma cruzi Dihydroorotate Dehydrogenase Active Site Plasticity for the Discovery of Potent and Selective Inhibitors with Trypanocidal Activity To be Published
5OWI	The dynamic dimer structure of the chaperone Trigger Factor (conformer 1) 分子名称: Trigger factor 著者 Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. 登録日 2017-09-01 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
6LKD	in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor 分子名称: 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Mimasu, S, Yamagishi, H, Kiyohara, M, Kakefuda, K, Okuda, T. 登録日 2019-12-19 公開日 2020-12-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4, 2021
5OWJ	The dynamic dimer structure of the chaperone Trigger Factor (conformer 2) 分子名称: Trigger factor 著者 Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. 登録日 2017-09-01 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
6LKE	in meso full-length rat KMO in complex with an inhibitor identified via DNA-encoded chemical library screening 分子名称: 4-chloranyl-2-[[5-chloranyl-2-(5-methoxy-1,3-dihydroisoindol-2-yl)-1,3-thiazol-4-yl]carbonyl-methyl-amino]-5-fluoranyl-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Mimasu, S, Yamagishi, H, Kiyohara, M, Hupp, D.C, Liu, J, Kakefuda, K, Okuda, T. 登録日 2019-12-19 公開日 2020-12-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4, 2021
6OTT	Structure of PurF in complex with ppApp 分子名称: Amidophosphoribosyltransferase, PurF, MAGNESIUM ION, ... 著者 Grant, R.A, Wang, B, Laub, M.T. 登録日 2019-05-03 公開日 2019-11-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp. Nature, 575, 2019
4MA0	The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP 分子名称: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-08-15 公開日 2013-08-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP To be Published
4MAM	The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP 分子名称: GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Phosphoribosylaminoimidazole carboxylase, ... 著者 Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-08-16 公開日 2013-08-28 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.474 Å) 主引用文献 The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP To be Published

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