3K9B
 
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8UX1
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5E7P
 | | Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein Cdc48, GLYCEROL, ... | | 著者 | Unciulac-Carp, M, Smith, P, Shuman, S. | | 登録日 | 2015-10-12 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.507 Å) | | 主引用文献 | Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).
J.Bacteriol., 198, 2016
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5OAI
 | | Structure of MDM2 with low molecular weight inhibitor | | 分子名称: | 3-[(1~{R})-2-(~{tert}-butylamino)-1-[methanoyl-[[3,4,5-tris(fluoranyl)phenyl]methyl]amino]-2-oxidanylidene-ethyl]-6-chloranyl-1~{H}-indole-2-carboxylic acid, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Twarda-Clapa, A, Neochoritis, C.G, Grudnik, P, Dubin, G, Domling, A, Holak, T.A. | | 登録日 | 2017-06-22 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wtosteosarcoma cells.
Febs J., 286, 2019
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6DU5
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7Y5V
 | | Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | | 著者 | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | | 登録日 | 2022-06-17 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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4PH4
 | | The crystal structure of Human VPS34 in complex with PIK-III | | 分子名称: | 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | | 著者 | Knapp, M.S, Elling, R.A. | | 登録日 | 2014-05-04 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat.Cell Biol., 16, 2014
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8CXL
 | | Structure of NapH3, a vanadium-dependent haloperoxidase homolog catalyzing the stereospecific alpha-hydroxyketone rearrangement reaction in napyradiomycin biosynthesis | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NapH3 | | 著者 | Chen, P.Y.-T, Chekan, J.R, Moore, B.S. | | 登録日 | 2022-05-21 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Biochemistry, 61, 2022
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8D4I
 | | Structure of Y430F D-ornithine/D-lysine decarboxylase complex with putrescine | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Phillips, R.S, Nguyen Hoang, K.N. | | 登録日 | 2022-06-02 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
Arch.Biochem.Biophys., 731, 2022
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8D5R
 | | Structure of Y430F D-ornithine/D-lysine decarboxylase complex with D-ornithine | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ACETATE ION, ... | | 著者 | Phillips, R.S, Nguyen Hoang, K.N. | | 登録日 | 2022-06-06 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
Arch.Biochem.Biophys., 731, 2022
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8D2Y
 | | Y430F mutant of D-ornithine/D-lysine decarboxylase | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... | | 著者 | Phillips, R.S, Nguyen Hoang, K.N. | | 登録日 | 2022-05-31 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
Arch.Biochem.Biophys., 731, 2022
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6DU4
 | | Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, ... | | 著者 | Doxtader, K, Wang, P, Nam, Y. | | 登録日 | 2018-06-19 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Mol. Cell, 71, 2018
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7ZI4
 | | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | | 登録日 | 2022-04-07 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
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2K7E
 | | NMR structure of the human tRNALys3 bound to the HIV genome Loop I | | 分子名称: | RNA (5'-R(*CP*UP*(SUR)P*UP*UP*AP*AP*(PSU)P*CP*UP*GP*C)-3'), RNA (5'-R(*GP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*G)-3') | | 著者 | Bilbille, Y, Vendeix, F.P.A, Guenther, R, Malkiewicz, A, Ariza, X, Vilarrasa, J, Agris, P. | | 登録日 | 2008-08-09 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the human tRNALys3 anticodon bound to the HIV genome is stabilized by modified nucleosides and adjacent mismatch base pairs.
Nucleic Acids Res., 37, 2009
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7VRX
 | | Pad-1 in the absence of substrate | | 分子名称: | Aminotransferase, SULFATE ION | | 著者 | Choi, M, Rhee, S. | | 登録日 | 2021-10-25 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.96634674 Å) | | 主引用文献 | Structural and biochemical basis for the substrate specificity of Pad-1, an indole-3-pyruvic acid aminotransferase in auxin homeostasis.
J.Struct.Biol., 214, 2022
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7Y5K
 | | Crystal structure of human CAF-1 core complex in spacegroup C2221 | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | | 登録日 | 2022-06-17 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5O
 | | Crystal structure of human CAF-1 core complex in spacegroup P21 | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | | 登録日 | 2022-06-17 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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7Y5L
 | | Crystal structure of human CAF-1 core complex in spacegroup C2 | | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | | 登録日 | 2022-06-17 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
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2L2N
 | | Backbone 1H, 13C, and 15N Chemical Shift Assignments for the first dsRBD of protein HYL1 | | 分子名称: | Hyponastic leave 1 | | 著者 | Rasia, R.M, Mateos, J.L, Bologna, N.G, Burdisso, P, Imbert, L, Palatnik, J.F, Boisbouvier, J. | | 登録日 | 2010-08-23 | | 公開日 | 2010-09-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and RNA Interactions of the Plant MicroRNA Processing-Associated Protein HYL1.
Biochemistry, 49, 2010
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2MCO
 | | Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence | | 分子名称: | SODIUM ION, human telomere quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+) L enantiomer | | 著者 | Williamson, M.P, Wilson, T, Thomas, J.A, Felix, V, Costa, P.J. | | 登録日 | 2013-08-22 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence.
J.Med.Chem., 56, 2013
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2MCC
 | | Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence | | 分子名称: | human_telomere_quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+) | | 著者 | Williamson, M.P, Wilson, T, Thomas, J.A, Felix, V, Costa, P.J. | | 登録日 | 2013-08-18 | | 公開日 | 2013-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence.
J.Med.Chem., 56, 2013
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2L2M
 | | Solution structure of the second dsRBD of HYL1 | | 分子名称: | Hyponastic leave 1 | | 著者 | Rasia, R.M, Mateos, J.L, Bologna, N.G, Burdisso, P, Imbert, L, Palatnik, J.F, Boisbouvier, J. | | 登録日 | 2010-08-22 | | 公開日 | 2010-09-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and RNA Interactions of the Plant MicroRNA Processing-Associated Protein HYL1.
Biochemistry, 49, 2010
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2O5F
 | | Crystal Structure of DR0079 from Deinococcus radiodurans at 1.9 Angstrom Resolution | | 分子名称: | Putative Nudix hydrolase DR_0079 | | 著者 | Kennedy, M.A, Buchko, G.W, Ni, S, Robinson, H. | | 登録日 | 2006-12-05 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Functional and Structural Characterization of DR_0079 from Deinococcus radiodurans, a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5'-Di- and Triphosphates.
Biochemistry, 47, 2008
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8BCH
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6XNV
 | | CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES CBPB PROTEIN (LMO1009) IN COMPLEX WITH C-DI-AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CBS domain-containing protein | | 著者 | Luo, S, Tong, L. | | 登録日 | 2020-07-04 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.
Mbio, 11, 2020
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