2MCC

Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence

Summary for 2MCC

• Entry DOI: 10.2210/pdb2mcc/pdb
• Related: 2MCO
• NMR Information: BMRB: 19435
• Descriptor: human_telomere_quadruplex, tetrakis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)(mu-tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine-1kappa~2~N~4~,N~5~:2kappa~2~N~13~,N~14~)diruthenium(4+) (2 entities in total)
• Functional Keywords: dna, quadruplex, complex, ruthenium
• Total number of polymer chains: 1
• Total formula weight: 8194.76

Authors

Williamson, M.P.,Wilson, T.,Thomas, J.A.,Felix, V.,Costa, P.J. (deposition date: 2013-08-18, release date: 2013-10-02, Last modification date: 2023-06-14)

• Primary citation: Wilson, T.,Costa, P.J.,Felix, V.,Williamson, M.P.,Thomas, J.A.; Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence.; J.Med.Chem., 56:8674-8683, 2013; PubMed: 24088028; DOI: 10.1021/jm401119b

Experimental method

SOLUTION NMR