1AE9
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6UGY
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![BU of 6ugy by Molmil](/molmil-images/mine/6ugy) | Crystal structure of the Fc fragment of anti-TNFa antibody infliximab (Remicade) in a primative orthorhombic crystal form, Lot C | 分子名称: | ACETATE ION, Remicade Fc, ZINC ION, ... | 著者 | Mayclin, S.J, Edwards, T.E. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6OOR
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![BU of 6oor by Molmil](/molmil-images/mine/6oor) | Structure of 1B1 bound to mouse CD1d | 分子名称: | Antibody 1B1 Heavy chain, Antibody 1B1 Light chain, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Ying, G, Zajonc, D.M. | 登録日 | 2019-04-23 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1. J.Biol.Chem., 294, 2019
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5HPW
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![BU of 5hpw by Molmil](/molmil-images/mine/5hpw) | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Singh, R.P, Singh, A, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2016-01-21 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination To Be Published
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4X58
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![BU of 4x58 by Molmil](/molmil-images/mine/4x58) | Anthranilate phosphoribosyl transferase variant N138A from Mycobacterium tuberculosis in complex with PRPP and Mg | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, D-MALATE, ... | 著者 | Cookson, T.V.M, Evans, G.L, Parker, E.J, Lott, J.S. | 登録日 | 2014-12-04 | 公開日 | 2015-11-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site. Biochemistry, 54, 2015
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1A96
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![BU of 1a96 by Molmil](/molmil-images/mine/1a96) | XPRTASE FROM E. COLI WITH BOUND CPRPP AND XANTHINE | 分子名称: | 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, BORIC ACID, MAGNESIUM ION, ... | 著者 | Vos, S, Parry, R.J, Burns, M.R, De Jersey, J, Martin, J.L. | 登録日 | 1998-04-16 | 公開日 | 1998-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase. J.Mol.Biol., 282, 1998
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7PY4
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![BU of 7py4 by Molmil](/molmil-images/mine/7py4) | Cryo-EM structure of ATP8B1-CDC50A in E2P autoinhibited state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Dieudonne, T, Abad-Herrera, S, Juknaviciute Laursen, M, Lejeune, M, Stock, C, Slimani, K, Jaxel, C, Lyons, J.A, Montigny, C, Gunther Pomorski, T, Nissen, P, Lenoir, G. | 登録日 | 2021-10-08 | 公開日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders. Elife, 11, 2022
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7N97
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![BU of 7n97 by Molmil](/molmil-images/mine/7n97) | State 2 of TcdB and FZD2 at pH5 | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of the Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9Q
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![BU of 7n9q by Molmil](/molmil-images/mine/7n9q) | State 3 of TcdB and FZD2 at pH5 | 分子名称: | Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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8SMI
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![BU of 8smi by Molmil](/molmil-images/mine/8smi) | Crystal structure of antibody WRAIR-2123 in complex with SARS-CoV-2 receptor binding domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, WRAIR-2123 Fab heavy chain, ... | 著者 | Sankhala, R.S, Jensen, J.L, Joyce, M.G. | 登録日 | 2023-04-26 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Antibody targeting of conserved sites of vulnerability on the SARS-CoV-2 spike receptor-binding domain. Structure, 32, 2024
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7N9S
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![BU of 7n9s by Molmil](/molmil-images/mine/7n9s) | TcdB and frizzled-2 CRD complex | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9R
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![BU of 7n9r by Molmil](/molmil-images/mine/7n9r) | state 4 of TcdB and FZD2 at pH5 | 分子名称: | Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9Y
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![BU of 7n9y by Molmil](/molmil-images/mine/7n9y) | Full-length TcdB and CSPG4 (401-560) complex | 分子名称: | Chondroitin sulfate proteoglycan 4, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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4WUT
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![BU of 4wut by Molmil](/molmil-images/mine/4wut) | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM AGROBACTERIUM VITIS (Avi_5133, TARGET EFI-511220) WITH BOUND D-FUCOSE | 分子名称: | ABC transporter substrate binding protein (Ribose), CALCIUM ION, CHLORIDE ION, ... | 著者 | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-11-03 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM AGROBACTERIUM VITIS (Avi_5133, TARGET EFI-511220) WITH BOUND D-FUCOSE To be published
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6YQQ
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![BU of 6yqq by Molmil](/molmil-images/mine/6yqq) | ForT-PRPP complex | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, CHLORIDE ION, ForT-PRPP complex, ... | 著者 | Naismith, J.H, Gao, S. | 登録日 | 2020-04-18 | 公開日 | 2020-05-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Uncovering the chemistry of C-C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex. Chem.Commun.(Camb.), 56, 2020
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7N95
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![BU of 7n95 by Molmil](/molmil-images/mine/7n95) | state 1 of TcdB and FZD2 at pH5 | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-16 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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1AWR
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![BU of 1awr by Molmil](/molmil-images/mine/1awr) | CYPA COMPLEXED WITH HAGPIA | 分子名称: | CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN | 著者 | Vajdos, F.F. | 登録日 | 1997-10-04 | 公開日 | 1998-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein. Protein Sci., 6, 1997
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5S9L
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![BU of 5s9l by Molmil](/molmil-images/mine/5s9l) | AUTOTAXIN, 4-[3-Oxo-3-(2-oxo-2,3-dihydro-benzooxazol-6-yl)-propyl]-piperazine-1-carboxylic acid 3,5-dichloro-benzyl ester, 1.90A, P212121, Rfree=19.1% | 分子名称: | (3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate, ACETATE ION, CALCIUM ION, ... | 著者 | Stihle, M, Hunziker, D, Benz, J, Mattei, P, Rudolph, M.G. | 登録日 | 2021-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of a rat Autotaxin complex To be published
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5S9M
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![BU of 5s9m by Molmil](/molmil-images/mine/5s9m) | AUTOTAXIN, (3,5-dichlorophenyl)methyl (3aS,8aR)-2-(1H-benzotriazole-5-carbonyl)-1,3,3a,4,5,7,8,8a-octahydropyrrolo[3,4-d]azepine-6-carboxylate, 1.80A, P212121, Rfree=21.1% | 分子名称: | (3,5-dichlorophenyl)methyl (3aR,8aS)-2-(1H-benzotriazole-5-carbonyl)octahydropyrrolo[3,4-d]azepine-6(1H)-carboxylate, ACETATE ION, CALCIUM ION, ... | 著者 | Stihle, M, Hunziker, D, Benz, J, Mattei, P, Rudolph, M.G. | 登録日 | 2021-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of a rat Autotaxin complex To be published
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5S9N
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![BU of 5s9n by Molmil](/molmil-images/mine/5s9n) | AUTOTAXIN, [4-(trifluoromethoxy)phenyl]methyl (3aS,6aS)-2-(1H-benzotriazole-5-carbonyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate, 1.80A, P212121, Rfree=23.3% | 分子名称: | CALCIUM ION, CHLORIDE ION, Isoform 2 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... | 著者 | Stihle, M, Hunziker, D, Benz, J, Mattei, P, Rudolph, M.G. | 登録日 | 2021-03-31 | 公開日 | 2022-04-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of a rat Autotaxin complex To be published
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7PEM
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![BU of 7pem by Molmil](/molmil-images/mine/7pem) | Cryo-EM structure of phophorylated Drs2p-Cdc50p in a PS and ATP-bound E2P state | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Timcenko, M, Wang, Y, Lyons, J.A, Nissen, P, Lindorff-Larsen, K. | 登録日 | 2021-08-10 | 公開日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Substrate Transport and Specificity in a Phospholipid Flippase To Be Published
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1APZ
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![BU of 1apz by Molmil](/molmil-images/mine/1apz) | |
8SSZ
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8ST3
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![BU of 8st3 by Molmil](/molmil-images/mine/8st3) | |
8EME
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![BU of 8eme by Molmil](/molmil-images/mine/8eme) | EGFR(T790M/V948R) in complex with ZNL-0056 | 分子名称: | Epidermal growth factor receptor, N-{7-methyl-1-[(3S)-1-(prop-2-enoyl)azepan-3-yl]-1H-benzimidazol-2-yl}-5-(prop-2-enamido)thiophene-3-carboxamide | 著者 | Beyett, T.S, Eck, M.J. | 登録日 | 2022-09-27 | 公開日 | 2023-10-18 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. Acs Cent.Sci., 10, 2024
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