PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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6QWB	Crystal structure of KPC-4 complexed with relebactam (16 hour soak) 分子名称: (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, (2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic acid, Beta-lactamase, ... 著者 Tooke, C.L, Hinchliffe, P, Spencer, J. 登録日 2019-03-05 公開日 2019-08-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Molecular Basis of Class A beta-Lactamase Inhibition by Relebactam. Antimicrob.Agents Chemother., 63, 2019
6HAO	MamM CTD H264E - Cadmium form 2 分子名称: BETA-MERCAPTOETHANOL, CADMIUM ION, Magnetosome protein MamM, ... 著者 Barber-Zucker, S, Zarivach, R. 登録日 2018-08-08 公開日 2019-08-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 MamM CTD H264E - Cadmium form 2 To Be Published
7LP8	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 分子名称: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W. 登録日 2021-02-11 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 To Be Published
6HAS	Crystal Structure of the small subunit-like domain of Rubisco activase from Nostoc sp. (strain PCC 7120) 分子名称: NICKEL (II) ION, Ribulose bisphosphate carboxylase/oxygenase activase 著者 Popilka, L, Bracher, A. 登録日 2018-08-08 公開日 2020-01-15 最終更新日 2021-01-27 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell, 183, 2020
5ETK	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.09 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
6Z9D	Human Ecto-5'-nucleotidase (CD73) in complex with AOPCP derivative AB680 (compound 55 in publication) in the closed form (crystal form III) 分子名称: 5'-nucleotidase, CALCIUM ION, ZINC ION, ... 著者 Strater, N. 登録日 2020-06-03 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of AB680: A Potent and Selective Inhibitor of CD73. J.Med.Chem., 63, 2020
7QRK	Human Carbonic Anhydrase II in complex with N-(2-aminophenyl)-4-((2-oxo-2-((4-sulfamoylphenethyl)amino)ethyl)amino)benzamide 分子名称: Carbonic anhydrase 2, GLYCEROL, N-(2-aminophenyl)-4-((2-oxo-2-((4-sulfamoylphenethyl)amino)ethyl)amino)benzamide, ... 著者 Angeli, A, Ferraroni, M. 登録日 2022-01-11 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.428 Å) 主引用文献 Human Carbonic Anhydrase II in complex with N-(2-aminophenyl)-4-((2-oxo-2-((4-sulfamoylphenethyl)amino)ethyl)amino)benzamide To Be Published
5ETO	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.07 angstrom resolution 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 4-[(2-azanyl-6-oxidanylidene-1,9-dihydropurin-8-yl)sulfanylmethyl]-3-fluoranyl-benzenecarbonitrile, CALCIUM ION, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
7QQ2	CRYSTAL STRUCTURE OF AS-ISOLATED S321M MUTANT OF THREE-DOMAIN HEME-CU NITRITE REDUCTASE FROM RALSTONIA PICKETTII 分子名称: COPPER (II) ION, Copper-containing nitrite reductase, HEME C 著者 Petchyam, N, Antonyuk, S, Hasnain, S.S. 登録日 2022-01-06 公開日 2023-01-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of haem three-domain copper nitrite reductase mutants from Ralstonia pickettii To Be Published
6HBT	The structure of the G. violaceus guanidine II riboswitch P2 stem-loop with arcaine 分子名称: 1-(4-carbamimidamidobutyl)guanidine, RNA (5'-R(*GP*GP*UP*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*AP*(CBV)P*C)-3'), SULFATE ION 著者 Huang, L, Lilley, D.M.J. 登録日 2018-08-13 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structure-guided design of a high-affinity ligand for a riboswitch. Rna, 25, 2019
7LNY	Apo structure of the Histone chaperone ASF1A residues 1-155 分子名称: Histone chaperone ASF1A 著者 Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E. 登録日 2021-02-08 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun, 13, 2022
5ETL	E. coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.82 angstrom resolution 分子名称: 2-[(2-azanyl-6-oxidanylidene-3,9-dihydropurin-8-yl)sulfanylmethyl]benzenecarbonitrile, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2015-11-17 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli. J.Med.Chem., 59, 2016
5EYL	TUBULIN-BINDING DARPIN 分子名称: DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, PHOSPHATE ION 著者 Ahmad, S, Kossow, M, Gigant, B. 登録日 2015-11-25 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep, 6, 2016
6G85	Structure of Cdc14 bound to CBK1 PxL motif 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CBK1, ... 著者 Mouilleron, S, Kataria, M, Uhlmann, F. 登録日 2018-04-07 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.528 Å) 主引用文献 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
8STC	S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zinc and soaked with bicarbonate. 分子名称: MAGNESIUM ION, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, ZINC ION 著者 Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R.P. 登録日 2023-05-09 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zinc and soaked with bicarbonate. To be published
5W1H	Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer) 分子名称: GLYCEROL, IODIDE ION, LbaCas13a (C2c2), ... 著者 Knott, G.J, Doudna, J.A. 登録日 2017-06-03 公開日 2017-09-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nat. Struct. Mol. Biol., 24, 2017
6HDY	Crystal structure of 2-Hydroxyisobutyryl-CoA Ligase (HCL) in the postadenylation state in complex with S3-HB-AMP 分子名称: (3S)-3-HYDROXYBUTANOIC ACID, 2-hydroxyisobutyryl-CoA synthetase, SULFATE ION, ... 著者 Zahn, M, Rohwerder, T, Strater, N. 登録日 2018-08-20 公開日 2019-08-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of 2-Hydroxyisobutyric Acid-CoA Ligase Reveal Determinants of Substrate Specificity and Describe a Multi-Conformational Catalytic Cycle. J.Mol.Biol., 431, 2019
6GBA	A fast recovering full-length LOV protein (DsLOV) from the marine phototrophic bacterium Dinoroseobacter shibae (Dark state) - M49A mutant 分子名称: FLAVIN MONONUCLEOTIDE, Putative blue-light photoreceptor 著者 Granzin, J, Batra-Safferling, R, Roellen, K. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanistic Basis of the Fast Dark Recovery of the Short LOV Protein DsLOV from Dinoroseobacter shibae. Biochemistry, 57, 2018
7LQD	Structure of Human MPS1 (TTK) covalently bound to RMS-07 inhibitor 分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Dual specificity protein kinase TTK or monopolar spindle 1 kinase, GLYCEROL, ... 著者 Santiago, A.S, dos Reis, C.V, Serafim, R.A.M, Massirer, K.B, Arruda, P, Edwards, A.M, Counago, R.M, Structural Genomics Consortium (SGC) 登録日 2021-02-13 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. J.Med.Chem., 65, 2022
6HE6	Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with dodecane-trimethylamine 分子名称: Cell division protein FtsX, DODECANE-TRIMETHYLAMINE 著者 Martinez-Caballero, S, Alcorlo-Pages, M, Hermoso, J.A. 登録日 2018-08-20 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. Mbio, 10, 2019
6D5X	Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, Adenosylcobalamin, and Triphosphate 分子名称: 5'-DEOXYADENOSINE, ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, ... 著者 Dodge, G.J, Campanello, G, Smith, J.L, Banerjee, R. 登録日 2018-04-19 公開日 2018-10-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12as a Cofactor Conservation Strategy. J. Am. Chem. Soc., 140, 2018
7LP7	The crystal structure of the wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 分子名称: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W. 登録日 2021-02-11 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 To Be Published
8RUM	Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and intronistat B 分子名称: Domains 1-5, MAGNESIUM ION, ~{N}-(2-pyrrolidin-1-ylethyl)-2-[3,4,5-tris(oxidanyl)phenyl]carbonyl-1-benzofuran-5-carboxamide 著者 Silvestri, I, Marcia, M. 登録日 2024-01-31 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (3.62 Å) 主引用文献 Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
6ZAS	Damage-free as-isolated copper nitrite reductase from Bradyrhizobium sp. ORS 375 (two-domain) determined by serial femtosecond rotation crystallography 分子名称: COPPER (II) ION, Copper-containing nitrite reductase, SULFATE ION 著者 Rose, S.L, Antonyuk, S.V, Sasaki, D, Yamashita, K, Hirata, K, Ueno, G, Ago, H, Eady, R.R, Tosha, T, Yamamoto, M, Hasnain, S.S. 登録日 2020-06-05 公開日 2021-01-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An unprecedented insight into the catalytic mechanism of copper nitrite reductase from atomic-resolution and damage-free structures. Sci Adv, 7, 2021
5ETI	Structure of dead kinase MAPK14 分子名称: Mitogen-activated protein kinase 14 著者 Pellegrini, E, Bowler, M.W. 登録日 2015-11-17 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Architecture of the MKK6-p38 alpha complex defines the basis of MAPK specificity and activation. Science, 381, 2023

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