8RUM

Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and intronistat B

Summary for 8RUM

• Entry DOI: 10.2210/pdb8rum/pdb
• Related: 4E8M 4E8N 4E8P 4E8Q 4E8R 4E8V 4FAQ 4FAR 4FAU 4FAX 8OLS 8OLV 8OLW
• Descriptor: Domains 1-5, ~{N}-(2-pyrrolidin-1-ylethyl)-2-[3,4,5-tris(oxidanyl)phenyl]carbonyl-1-benzofuran-5-carboxamide, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: ribozyme, metalloenzyme, self-splicing, retrotransposition, rna
• Biological source: Oceanobacillus iheyensis
• Total number of polymer chains: 1
• Total formula weight: 129350.10

Authors

Silvestri, I.,Marcia, M. (deposition date: 2024-01-31, release date: 2024-06-19)

• Primary citation: Silvestri, I.,Manigrasso, J.,Andreani, A.,Brindani, N.,Mas, C.,Reiser, J.B.,Vidossich, P.,Martino, G.,McCarthy, A.,De Vivo, M.,Marcia, M.; Targeting the conserved active site of splicing machines with specific and selective small molecule modulators; Nat Commun, 2024; DOI: 10.1038/s41467-024-48697-0

Experimental method

X-RAY DIFFRACTION (3.62 Å)