4V6D
| Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | 登録日 | 2009-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
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4V6S
| Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-09 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (13.1 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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4V79
| E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post3b) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | 登録日 | 2013-10-14 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (15 Å) | 主引用文献 | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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4V6Y
| E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | 登録日 | 2013-10-14 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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4V7C
| Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA structure) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. | 登録日 | 2013-11-20 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc.Natl.Acad.Sci.USA, 110, 2013
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4V55
| Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF). | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | 著者 | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | 登録日 | 2007-06-17 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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4V6O
| Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (14.7 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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4V70
| E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | 登録日 | 2013-10-14 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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3BQZ
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4V7T
| Crystal structure of the E. coli ribosome bound to chloramphenicol. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | 登録日 | 2010-08-14 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1942 Å) | 主引用文献 | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V77
| E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post2b) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | 登録日 | 2013-10-14 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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4V66
| Structure of the E. coli ribosome and the tRNAs in Post-accommodation state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Devkota, B, Caulfield, T.R, Tan, R.-Z, Harvey, S.C. | 登録日 | 2008-08-03 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading To be Published
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4V6V
| Tetracycline resistance protein Tet(O) bound to the ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Li, W, Atkinson, G.C, Thakor, N.S, Allas, U, Lu, C, Chan, K.Y, Tenson, T, Schulten, K, Wilson, K.S, Hauryliuk, V, Frank, J. | 登録日 | 2013-02-25 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | Mechanism of tetracycline resistance by ribosomal protection protein Tet(O). Nat Commun, 4, 2013
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4V7A
| E. coli 70S-fMetVal-tRNAVal post-translocation complex (post4) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | 登録日 | 2013-10-14 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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4WF1
| Crystal structure of the E. coli ribosome bound to negamycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. | 登録日 | 2014-09-11 | 公開日 | 2014-11-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
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4WWW
| Crystal structure of the E. coli ribosome bound to CEM-101 | 分子名称: | (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... | 著者 | Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. | 登録日 | 2014-11-12 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
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9FMD
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7OS9
| Crystal Structure of Domain Swapped Trp Repressor V58I Variant with purification tag | 分子名称: | IMIDAZOLE, Trp operon repressor | 著者 | Sprenger, J, Lawson, C.L, Lo Leggio, L, Von Wachenfeldt, C, Carey, J. | 登録日 | 2021-06-08 | 公開日 | 2021-07-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan. Acta Crystallogr.,Sect.F, 77, 2021
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6O7K
| 30S initiation complex | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | 登録日 | 2019-03-08 | 公開日 | 2019-05-29 | 最終更新日 | 2020-01-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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3KYC
| Human SUMO E1 complex with a SUMO1-AMP mimic | 分子名称: | 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ... | 著者 | Lima, C.D. | 登録日 | 2009-12-05 | 公開日 | 2010-02-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
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3KYD
| Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic | 分子名称: | 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ... | 著者 | Lima, C.D. | 登録日 | 2009-12-05 | 公開日 | 2010-02-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
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5LN3
| The human 26S Proteasome at 6.8 Ang. | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P. | 登録日 | 2016-08-03 | 公開日 | 2017-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol. Cell Proteomics, 16, 2017
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3BUE
| Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis | 分子名称: | Arginine repressor ArgR | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2008-01-02 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
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3CAG
| Crystal structure of the oligomerization domain hexamer of the arginine repressor protein from Mycobacterium tuberculosis in complex with 9 arginines. | 分子名称: | ARGININE, Arginine repressor | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2008-02-19 | 公開日 | 2008-03-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
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8E32
| E. coli 50S ribosome bound to compound streptogramin analogs SA1 and SB1 | 分子名称: | (3R,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-yn-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione, 23S ribosomal RNA, 50S ribosomal protein L13, ... | 著者 | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | 登録日 | 2022-08-16 | 公開日 | 2023-06-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | Potential for clicked streptogramin analogs To Be Published
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