8P03
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p03 by Molmil](/molmil-images/mine/8p03) | 48S late-stage initiation complex with m6A mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | 登録日 | 2023-05-09 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
|
|
7SYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7syp by Molmil](/molmil-images/mine/7syp) | Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt) | 分子名称: | 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
|
|
7SYQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7syq by Molmil](/molmil-images/mine/7syq) | Structure of the wt IRES and 40S ribosome ternary complex, open conformation. Structure 11(wt) | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
|
|
7SYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sys by Molmil](/molmil-images/mine/7sys) | Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII). | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
|
|
7SYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7syr by Molmil](/molmil-images/mine/7syr) | Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt). | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-27 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
|
|
6SB2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sb2 by Molmil](/molmil-images/mine/6sb2) | cryo-EM structure of mTORC1 bound to active RagA/C GTPases | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... | 著者 | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | 登録日 | 2019-07-18 | 公開日 | 2019-10-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
|
|
2O25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o25 by Molmil](/molmil-images/mine/2o25) | Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 | 分子名称: | SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-29 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa To be Published
|
|
7W3B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3b by Molmil](/molmil-images/mine/7w3b) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W37
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w37 by Molmil](/molmil-images/mine/7w37) | Structure of USP14-bound human 26S proteasome in state EA1_UBL | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3g by Molmil](/molmil-images/mine/7w3g) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3k by Molmil](/molmil-images/mine/7w3k) | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3c by Molmil](/molmil-images/mine/7w3c) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3f by Molmil](/molmil-images/mine/7w3f) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w38 by Molmil](/molmil-images/mine/7w38) | Structure of USP14-bound human 26S proteasome in state EA2.0_UBL | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3m by Molmil](/molmil-images/mine/7w3m) | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3i by Molmil](/molmil-images/mine/7w3i) | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3h by Molmil](/molmil-images/mine/7w3h) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3j by Molmil](/molmil-images/mine/7w3j) | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W39
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w39 by Molmil](/molmil-images/mine/7w39) | Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7W3A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w3a by Molmil](/molmil-images/mine/7w3a) | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
|
|
7JVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvx by Molmil](/molmil-images/mine/7jvx) | Crystal structure of PTEN (aa 7-353 followed by spacer TGGGSGGTGGGSGGTGGGCY ligated to peptide pSDpTpTDpSDPENEPFDED) | 分子名称: | PHOSPHATE ION, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | 著者 | Dempsey, D, Phan, K, Cole, P, Gabelli, S.B. | 登録日 | 2020-08-24 | 公開日 | 2021-08-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structural basis of PTEN regulation by multi-site phosphorylation. Nat.Struct.Mol.Biol., 28, 2021
|
|
5LJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lj5 by Molmil](/molmil-images/mine/5lj5) | Overall structure of the yeast spliceosome immediately after branching. | 分子名称: | CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | 登録日 | 2016-07-17 | 公開日 | 2016-08-31 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
|
|
5MQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mq0 by Molmil](/molmil-images/mine/5mq0) | Structure of a spliceosome remodeled for exon ligation | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-19 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
|
|
4D61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d61 by Molmil](/molmil-images/mine/4d61) | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-07 | 公開日 | 2015-03-04 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
|
|
6SB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sb0 by Molmil](/molmil-images/mine/6sb0) | cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ... | 著者 | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | 登録日 | 2019-07-18 | 公開日 | 2019-10-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
|
|