1E8W
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![BU of 1e8w by Molmil](/molmil-images/mine/1e8w) | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. | 登録日 | 2000-10-03 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
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1E92
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![BU of 1e92 by Molmil](/molmil-images/mine/1e92) | Pteridine reductase 1 from Leishmania major complexed with NADP+ and dihydrobiopterin | 分子名称: | 1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schuettelkopf, A.W, Hunter, W.N. | 登録日 | 2000-10-04 | 公開日 | 2001-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites Nat.Struct.Biol., 8, 2001
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1E7Z
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![BU of 1e7z by Molmil](/molmil-images/mine/1e7z) | Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex | 分子名称: | ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, MERCURY (II) ION | 著者 | Pasqualato, S, Kerjan, P, Renault, L, Menetrey, J, Mirande, M, Cherfils, J. | 登録日 | 2000-09-13 | 公開日 | 2000-11-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of the Emapii Domain of Human Aminoacyl-tRNA Synthetase Complex Reveals Evolutionary Dimeric Mimicry Embo J., 20, 2001
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1E5I
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![BU of 1e5i by Molmil](/molmil-images/mine/1e5i) | DELTA-R306 DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH IRON AND 2-OXOGLUTARATE. | 分子名称: | 2-OXOGLUTARIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION | 著者 | Lee, H.J, Lloyd, M.D, Harlos, K, Clifton, I.J, Baldwin, J.E, Schofield, C.J. | 登録日 | 2000-07-26 | 公開日 | 2001-07-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs) J.Mol.Biol., 308, 2001
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1E90
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![BU of 1e90 by Molmil](/molmil-images/mine/1e90) | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. | 登録日 | 2000-10-03 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
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1E5Q
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![BU of 1e5q by Molmil](/molmil-images/mine/1e5q) | Ternary complex of saccharopine reductase from Magnaporthe grisea, NADPH and saccharopine | 分子名称: | N-(5-AMINO-5-CARBOXYPENTYL)GLUTAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Saccharopine dehydrogenase [NADP(+), ... | 著者 | Johansson, E, Steffens, J.J, Lindqvist, Y, Schneider, G. | 登録日 | 2000-07-28 | 公開日 | 2000-12-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Saccharopine Reductase from Magnaporthe Grisea, an Enzyme of the Alpha-Aminoadipate Pathway of Lysine Biosynthesis Structure, 8, 2000
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1EAC
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![BU of 1eac by Molmil](/molmil-images/mine/1eac) | |
1EAB
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![BU of 1eab by Molmil](/molmil-images/mine/1eab) | |
1EAD
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![BU of 1ead by Molmil](/molmil-images/mine/1ead) | |
1ECP
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![BU of 1ecp by Molmil](/molmil-images/mine/1ecp) | PURINE NUCLEOSIDE PHOSPHORYLASE | 分子名称: | PURINE NUCLEOSIDE PHOSPHORYLASE | 著者 | Mao, C, Ealick, S.E. | 登録日 | 1995-07-13 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology. Structure, 5, 1997
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1E8X
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![BU of 1e8x by Molmil](/molmil-images/mine/1e8x) | STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, LUTETIUM (III) ION, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. | 登録日 | 2000-10-03 | 公開日 | 2000-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
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1F45
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![BU of 1f45 by Molmil](/molmil-images/mine/1f45) | HUMAN INTERLEUKIN-12 | 分子名称: | INTERLEUKIN-12 ALPHA CHAIN, INTERLEUKIN-12 BETA CHAIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yoon, C, Johnston, S.C, Tang, J, Tobin, J.F, Somers, W.S. | 登録日 | 2000-06-07 | 公開日 | 2001-06-20 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12. EMBO J., 19, 2000
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1EZG
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![BU of 1ezg by Molmil](/molmil-images/mine/1ezg) | CRYSTAL STRUCTURE OF ANTIFREEZE PROTEIN FROM THE BEETLE, TENEBRIO MOLITOR | 分子名称: | THERMAL HYSTERESIS PROTEIN ISOFORM YL-1 | 著者 | Liou, Y.-C, Tocilj, A, Davies, P.L, Jia, Z. | 登録日 | 2000-05-10 | 公開日 | 2000-08-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Mimicry of ice structure by surface hydroxyls and water of a beta-helix antifreeze protein. Nature, 406, 2000
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1EZZ
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![BU of 1ezz by Molmil](/molmil-images/mine/1ezz) | |
1F3W
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![BU of 1f3w by Molmil](/molmil-images/mine/1f3w) | RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE | 分子名称: | MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... | 著者 | Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W. | 登録日 | 2000-06-06 | 公開日 | 2001-10-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase. J.Mol.Biol., 312, 2001
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1EZS
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![BU of 1ezs by Molmil](/molmil-images/mine/1ezs) | CRYSTAL STRUCTURE OF ECOTIN MUTANT M84R, W67A, G68A, Y69A, D70A BOUND TO RAT ANIONIC TRYPSIN II | 分子名称: | CALCIUM ION, ECOTIN, TRYPSIN II, ... | 著者 | Gillmor, S.A, Takeuchi, T, Yang, S.Q, Craik, C.S, Fletterick, R.J. | 登録日 | 2000-05-11 | 公開日 | 2000-06-23 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases. J.Mol.Biol., 299, 2000
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1EZW
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![BU of 1ezw by Molmil](/molmil-images/mine/1ezw) | STRUCTURE OF COENZYME F420 DEPENDENT TETRAHYDROMETHANOPTERIN REDUCTASE FROM METHANOPYRUS KANDLERI | 分子名称: | CHLORIDE ION, COENZYME F420-DEPENDENT N5,N10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE, MAGNESIUM ION | 著者 | Shima, S, Warkentin, E, Grabarse, W, Thauer, R.K, Ermler, U. | 登録日 | 2000-05-12 | 公開日 | 2000-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure of coenzyme F(420) dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea. J.Mol.Biol., 300, 2000
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1F3F
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![BU of 1f3f by Molmil](/molmil-images/mine/1f3f) | STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX | 分子名称: | 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-DIPHOSPHATE, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Meyer, P, Schneider, B, Sarfati, S, Deville-Bonne, D, Guerreiro, C, Boretto, J, Janin, J, Veron, M, Canard, B. | 登録日 | 2000-06-02 | 公開日 | 2000-09-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase. EMBO J., 19, 2000
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1F3P
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![BU of 1f3p by Molmil](/molmil-images/mine/1f3p) | FERREDOXIN REDUCTASE (BPHA4)-NADH COMPLEX | 分子名称: | FERREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Senda, T, Yamada, T, Sakurai, N, Kubota, M, Nishizaki, T, Masai, E, Fukuda, M, Mitsuidagger, Y. | 登録日 | 2000-06-06 | 公開日 | 2001-06-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of NADH-dependent ferredoxin reductase component in biphenyl dioxygenase. J.Mol.Biol., 304, 2000
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1EZP
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![BU of 1ezp by Molmil](/molmil-images/mine/1ezp) | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS | 分子名称: | MALTODEXTRIN BINDING PERIPLASMIC PROTEIN | 著者 | Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E. | 登録日 | 2000-05-11 | 公開日 | 2001-05-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. J.Mol.Biol., 300, 2000
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1F1H
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![BU of 1f1h by Molmil](/molmil-images/mine/1f1h) | |
1F3X
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![BU of 1f3x by Molmil](/molmil-images/mine/1f3x) | S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE | 分子名称: | MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... | 著者 | Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W. | 登録日 | 2000-06-06 | 公開日 | 2001-10-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase. J.Mol.Biol., 312, 2001
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1F42
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![BU of 1f42 by Molmil](/molmil-images/mine/1f42) | THE P40 DOMAIN OF HUMAN INTERLEUKIN-12 | 分子名称: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, INTERLEUKIN-12 BETA CHAIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yoon, C, Johnston, S.C, Tang, J, Tobin, J.F, Somers, W.S. | 登録日 | 2000-06-07 | 公開日 | 2001-06-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12. EMBO J., 19, 2000
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1F0Z
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![BU of 1f0z by Molmil](/molmil-images/mine/1f0z) | SOLUTION STRUCTURE OF THIS, THE SULFUR CARRIER PROTEIN IN E.COLI THIAMIN BIOSYNTHESIS | 分子名称: | THIS PROTEIN | 著者 | Wang, C, Xi, J, Begley, T.P, Nicholson, L.K. | 登録日 | 2000-05-17 | 公開日 | 2001-01-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of ThiS and implications for the evolutionary roots of ubiquitin. Nat.Struct.Biol., 8, 2001
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1EZR
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![BU of 1ezr by Molmil](/molmil-images/mine/1ezr) | CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | 分子名称: | CALCIUM ION, NUCLEOSIDE HYDROLASE | 著者 | Shi, W, Schramm, V.L, Almo, S.C. | 登録日 | 2000-05-11 | 公開日 | 2000-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. J.Biol.Chem., 274, 1999
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