PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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5W3U	Crystal structure of SsoPox AsB5 mutant (V27A-I76T-Y97W-Y99F-L130P-L226V) 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. 登録日 2017-06-08 公開日 2017-12-20 最終更新日 2021-08-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
4I1B	FUNCTIONAL IMPLICATIONS OF INTERLEUKIN-1BETA BASED ON THE THREE-DIMENSIONAL STRUCTURE 分子名称: INTERLEUKIN-1 BETA 著者 Veerapandian, B, Poulos, T.L, Gilliland, G.L, Raag, R, Svensson, L.A, Masui, Y, Hirai, Y. 登録日 1990-03-27 公開日 1990-04-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Functional implications of interleukin-1 beta based on the three-dimensional structure. Proteins, 12, 1992
4IBA	Bovine beta-lactoglobulin (isoform B) in complex with dodecyl sulphate (SDS) 分子名称: DODECYL SULFATE, GLYCEROL, beta-lactoglobulin 著者 Loch, J.I, Bonarek, P, Polit, A, Swiatek, S, Dziedzicka-Wasylewska, M, Lewinski, K. 登録日 2012-12-08 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The differences in binding 12-carbon aliphatic ligands by bovine beta-lactoglobulin isoform A and B studied by isothermal titration calorimetry and X-ray crystallography J.Mol.Recognit., 26, 2013
4IB7	Bovine beta-lactoglobulin (isoform A) in complex with dodecyltrimethylammonium (DTAC) 分子名称: DODECANE-TRIMETHYLAMINE, beta-lactoglobulin 著者 Loch, J.I, Bonarek, P, Polit, A, Swiatek, S, Dziedzicka-Wasylewska, M, Lewinski, K. 登録日 2012-12-08 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The differences in binding 12-carbon aliphatic ligands by bovine beta-lactoglobulin isoform A and B studied by isothermal titration calorimetry and X-ray crystallography J.Mol.Recognit., 26, 2013
1V4K	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima S77F mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
4LWE	Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ2 分子名称: Heat shock protein HSP 90-alpha, N-[3-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1,2-oxazol-5-yl]acetamide 著者 Li, J, Shi, F, Xiong, B, He, J. 登録日 2013-07-27 公開日 2014-07-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
1P8J	CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... 著者 Henrich, S, Cameron, A, Bourenkov, G.P, Kiefersauer, R, Huber, R, Lindberg, I, Bode, W, Than, M.E. 登録日 2003-05-07 公開日 2003-07-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Crystal Structure of the Proprotein Processing Proteinase Furin Explains its Stringent Specificity Nat.Struct.Biol., 10, 2003
4OGX	Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.4 Angstrom resolution 分子名称: DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, Plasma kallikrein, ... 著者 Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. 登録日 2014-01-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
4BCI	Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor 分子名称: 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide, CYCLIN-DEPENDENT KINASE 9, CYCLIN-T1 著者 Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. 登録日 2012-10-02 公開日 2013-01-09 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
4BCH	Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor 分子名称: 4-(4-methyl-2-methylimino-3H-1,3-thiazol-5-yl)-2-[(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)amino]pyrimidine-5-carbonitrile, CYCLIN-DEPENDENT KINASE 9, CYCLIN-T1, ... 著者 Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. 登録日 2012-10-02 公開日 2013-01-09 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (2.958 Å) 主引用文献 Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
4I72	Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with Immucillin A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R, CALCIUM ION, ... 著者 Giannese, F, Degano, M. 登録日 2012-11-30 公開日 2013-08-07 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor Acta Crystallogr.,Sect.D, 69, 2013
4BCK	Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor 分子名称: 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide, CYCLIN-A2, CYCLIN-DEPENDENT KINASE 2, ... 著者 Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. 登録日 2012-10-02 公開日 2013-03-06 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
1DFW	CONFORMATIONAL MAPPING OF THE N-TERMINAL SEGMENT OF SURFACTANT PROTEIN B IN LIPID USING 13C-ENHANCED FOURIER TRANSFORM INFRARED SPECTROSCOPY (FTIR) 分子名称: LUNG SURFACTANT PROTEIN B 著者 Gordon, L.M, Lee, K.Y.C, Lipp, M.M, Zasadzinski, J.A, Walther, F.J, Sherman, M.A, Waring, A.J. 登録日 1999-11-22 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 INFRARED SPECTROSCOPY 主引用文献 Conformational mapping of the N-terminal segment of surfactant protein B in lipid using 13C-enhanced Fourier transform infrared spectroscopy. J.Pept.Res., 55, 2000
1JNJ	NMR solution structure of the human beta2-microglobulin 分子名称: beta2-microglobulin 著者 Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G. 登録日 2001-07-24 公開日 2002-02-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition. Protein Sci., 11, 2002
4BCJ	Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor 分子名称: 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile, CYCLIN-DEPENDENT KINASE 9, CYCLIN-T1 著者 Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M. 登録日 2012-10-02 公開日 2013-01-09 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (3.162 Å) 主引用文献 Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity. J.Med.Chem., 56, 2013
1P6C	crystal structure of phosphotriesterase triple mutant H254G/H257W/L303T complexed with diisopropylmethylphosphonate 分子名称: DIETHYL 4-METHYLBENZYLPHOSPHONATE, METHYLPHOSPHONIC ACID DIISOPROPYL ESTER, Parathion hydrolase, ... 著者 Hill, C.M, Li, W, Thoden, J.B, Holden, H.M, Raushel, F.M. 登録日 2003-04-29 公開日 2003-09-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site. J.Am.Chem.Soc., 125, 2003
1W2I	Crystal structuore of acylphosphatase from Pyrococcus horikoshii complexed with formate 分子名称: ACYLPHOSPHATASE, FORMIC ACID 著者 Cheung, Y.Y, Lam, S.Y, Chu, W.K, Allen, M.D, Bycroft, M, Wong, K.B. 登録日 2004-07-06 公開日 2004-08-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of a Hyperthermophilic Archaeal Acylphosphatase from Pyrococcus Horikoshii-Structural Insights Into Enzymatic Catalysis, Thermostability, and Dimerization Biochemistry, 44, 2005
4IB6	Bovine beta-lactoglobulin (isoform A) in complex with lauric acid (C12) 分子名称: Beta-lactoglobulin, LAURIC ACID 著者 Loch, J.I, Bonarek, P, Polit, A, Swiatek, S, Dziedzicka-Wasylewska, M, Lewinski, K. 登録日 2012-12-08 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The differences in binding 12-carbon aliphatic ligands by bovine beta-lactoglobulin isoform A and B studied by isothermal titration calorimetry and X-ray crystallography J.Mol.Recognit., 26, 2013
1P63	Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I) 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION 著者 Brych, S.R, Kim, J, Logan, T.M, Blaber, M. 登録日 2003-04-28 公開日 2004-05-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Accommodation of a highly symmetric core within a symmetric protein superfold Protein Sci., 12, 2003
1PV4	X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA 分子名称: 5'-D(P*CP*C)-3', Transcription termination factor rho 著者 Skordalakes, E, Berger, J.M. 登録日 2003-06-26 公開日 2003-07-22 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading Cell(Cambridge,Mass.), 114, 2003
1PYN	DUAL-SITE POTENT, SELECTIVE PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR USING A LINKED FRAGMENT STRATEGY AND A MALONATE HEAD ON THE FIRST SITE 分子名称: 2-(4-{2-TERT-BUTOXYCARBONYLAMINO-2-[4-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-BUTYLCARBAMOYL]-ETHYL}-PHENOXY)-MALONIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 著者 Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Zhonghua, P, Lubben, T, Trevillyan, J.M, Stashko, M, Ballaron, S.J, Liang, H. 登録日 2003-07-09 公開日 2003-09-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem.Lett., 13, 2003
1PVO	X-ray crystal structure of Rho transcription termination factor in complex with ssRNA substrate and ANPPNP 分子名称: 5'-R(P*UP*C)-3', PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transcription termination factor rho 著者 Skordalakes, E, Berger, J.M. 登録日 2003-06-27 公開日 2003-07-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading Cell(Cambridge,Mass.), 114, 2003
5VRI	Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - closed form 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M. 登録日 2017-05-10 公開日 2017-12-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase. Sci Rep, 7, 2017
1UT4	Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors 分子名称: NO APICAL MERISTEM PROTEIN 著者 Ernst, H.A, Olsen, A.N, Skriver, K, Larsen, S, Lo Leggio, L. 登録日 2003-12-03 公開日 2004-03-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Conserved Domain of Anac, a Member of the Nac Family of Transcription Factors Embo Rep., 5, 2004
1PRC	CRYSTALLOGRAPHIC REFINEMENT AT 2.3 ANGSTROMS RESOLUTION AND REFINED MODEL OF THE PHOTOSYNTHETIC REACTION CENTER FROM RHODOPSEUDOMONAS VIRIDIS 分子名称: 15-trans-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ... 著者 Deisenhofer, J, Epp, O, Miki, K, Huber, R, Michel, H. 登録日 1988-02-04 公開日 1989-01-09 最終更新日 2021-03-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic refinement at 2.3 A resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis. J.Mol.Biol., 246, 1995

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