4TMT
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![BU of 4tmt by Molmil](/molmil-images/mine/4tmt) | Translation initiation factor eIF5B (517-858) mutant D533A from C. thermophilum, bound to GTPgammaS | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... | 著者 | Kuhle, B, Ficner, R. | 登録日 | 2014-06-02 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | A monovalent cation acts as structural and catalytic cofactor in translational GTPases. Embo J., 33, 2014
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6BPR
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![BU of 6bpr by Molmil](/molmil-images/mine/6bpr) | Crystal structure of cysteine, nitric oxide-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-11-26 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry, 58, 2019
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8OFB
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![BU of 8ofb by Molmil](/molmil-images/mine/8ofb) | Crystal Structure of T. maritima reverse gyrase with a minimal latch, hexagonal form | 分子名称: | CHLORIDE ION, HEXAETHYLENE GLYCOL, Reverse gyrase, ... | 著者 | Klostermeier, D, Rasche, R, Mhaindarkar, V, Kummel, D, Rudolph, M.G. | 登録日 | 2023-03-15 | 公開日 | 2023-04-26 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain. Acta Crystallogr D Struct Biol, 79, 2023
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4HGM
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![BU of 4hgm by Molmil](/molmil-images/mine/4hgm) | Shark IgNAR Variable Domain | 分子名称: | 1,2-ETHANEDIOL, ACETYL GROUP, Serum albumin, ... | 著者 | Olland, A, Kovalenko, O.V, King, D, Svenson, K. | 登録日 | 2012-10-08 | 公開日 | 2013-05-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis. J.Biol.Chem., 288, 2013
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5UVL
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![BU of 5uvl by Molmil](/molmil-images/mine/5uvl) | Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation | 分子名称: | CALCIUM ION, NITRATE ION, Proteinase K | 著者 | Martin-Garcia, J.M, Conrad, C.E, Nelson, G, Stander, N, Zatsepin, N.A, Zook, J, Zhu, L, Geiger, J, Chun, E, Kissick, D, Hilgart, M.C, Ogata, C, Ishchenko, A, Nagaratnam, N, Roy-Chowdhury, S, Coe, J, Subramanian, G, Schaffer, A, James, D, Ketawala, G, Venugopalan, N, Xu, S, Corcoran, S, Ferguson, D, Weierstall, U, Spence, J.C.H, Cherezov, V, Fromme, P, Fischetti, R.F, Liu, W. | 登録日 | 2017-02-20 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ, 4, 2017
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6BPU
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![BU of 6bpu by Molmil](/molmil-images/mine/6bpu) | Crystal structure of ferrous form of the F2-Tyr157 human cysteine dioxygenase with both uncrosslinked and crosslinked cofactor | 分子名称: | Cysteine dioxygenase type 1, FE (II) ION, GLYCEROL, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-11-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol., 14, 2018
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4TNH
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![BU of 4tnh by Molmil](/molmil-images/mine/4tnh) | RT XFEL structure of Photosystem II in the dark state at 4.9 A resolution | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K. | 登録日 | 2014-06-04 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.900007 Å) | 主引用文献 | Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy. Nat Commun, 5, 2014
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8OPI
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![BU of 8opi by Molmil](/molmil-images/mine/8opi) | VHH Z70 mutant 1 in interaction with PHF6 Tau peptide | 分子名称: | PHF6 Tau peptide, VHH Z70 mutant 1 | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | 登録日 | 2023-04-07 | 公開日 | 2023-05-31 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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8DYZ
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5LI6
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![BU of 5li6 by Molmil](/molmil-images/mine/5li6) | Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with N-isopropyl-N-((3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)-2-(4-nitrophenyl)acetamide | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 126, ~{N}-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]-2-(4-nitrophenyl)-~{N}-propan-2-yl-ethanamide | 著者 | Levy, C, Munro, A.W, Leys, D. | 登録日 | 2016-07-14 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J. Biol. Chem., 292, 2017
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6BKX
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![BU of 6bkx by Molmil](/molmil-images/mine/6bkx) | Novel Modes of Inhibition of Wild-Type IDH1: Direct Covalent Modification of His315 with Cmpd1 | 分子名称: | (6aS,7S,9R,10aS)-7,10a-dimethyl-8-oxo-2-(phenylamino)-5,6,6a,7,8,9,10,10a-octahydrobenzo[h]quinazoline-9-carbonitrile, CALCIUM ION, ISOCITRIC ACID, ... | 著者 | Jakob, C.G, Qiu, W. | 登録日 | 2017-11-09 | 公開日 | 2018-07-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J. Med. Chem., 61, 2018
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5LUT
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![BU of 5lut by Molmil](/molmil-images/mine/5lut) | Structures of DHBN domain of Gallus gallus BLM helicase | 分子名称: | BLM helicase, PHOSPHATE ION | 著者 | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | 登録日 | 2016-09-09 | 公開日 | 2017-03-01 | 最終更新日 | 2017-04-19 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
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4B3N
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![BU of 4b3n by Molmil](/molmil-images/mine/4b3n) | Crystal structure of rhesus TRIM5alpha PRY/SPRY domain | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5, ... | 著者 | Yang, H, Ji, X, Zhao, Q, Xiong, Y. | 登録日 | 2012-07-25 | 公開日 | 2012-10-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha Proc.Natl.Acad.Sci.USA, 109, 2012
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5LIN
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![BU of 5lin by Molmil](/molmil-images/mine/5lin) | |
7ZMH
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![BU of 7zmh by Molmil](/molmil-images/mine/7zmh) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Laube, E, Kuehlbrandt, W. | 登録日 | 2022-04-19 | 公開日 | 2022-11-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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4TMX
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![BU of 4tmx by Molmil](/molmil-images/mine/4tmx) | Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Kuhle, B, Ficner, R. | 登録日 | 2014-06-02 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A monovalent cation acts as structural and catalytic cofactor in translational GTPases. Embo J., 33, 2014
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8DZ7
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1K43
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![BU of 1k43 by Molmil](/molmil-images/mine/1k43) | 10 Structure Ensemble of the 14-residue peptide RG-KWTY-NG-ITYE-GR (MBH12) | 分子名称: | MBH12 | 著者 | Pastor, M.T, Lopez de la Paz, M, Lacroix, E, Serrano, L, Perez-Paya, E. | 登録日 | 2001-10-05 | 公開日 | 2001-10-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Combinatorial approaches: a new tool to search for highly structured beta-hairpin peptides. Proc.Natl.Acad.Sci.USA, 99, 2002
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5LVU
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![BU of 5lvu by Molmil](/molmil-images/mine/5lvu) | XiaF (apo) from Streptomyces sp. | 分子名称: | SULFATE ION, XiaF protein | 著者 | Kugel, S, Baunach, M, Baer, P, Ishida-Ito, M, Sundaram, S, Xu, Z, Groll, M, Hertweck, C. | 登録日 | 2016-09-14 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun, 8, 2017
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7ZM8
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![BU of 7zm8 by Molmil](/molmil-images/mine/7zm8) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Laube, E, Kuehlbrandt, W. | 登録日 | 2022-04-19 | 公開日 | 2022-11-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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7ZM7
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![BU of 7zm7 by Molmil](/molmil-images/mine/7zm7) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Laube, E, Kuehlbrandt, W. | 登録日 | 2022-04-19 | 公開日 | 2022-11-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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1B89
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![BU of 1b89 by Molmil](/molmil-images/mine/1b89) | CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) | 分子名称: | PROTEIN (CLATHRIN HEAVY CHAIN) | 著者 | Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K. | 登録日 | 1999-05-27 | 公開日 | 1999-06-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature, 399, 1999
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5LK2
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8OM9
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![BU of 8om9 by Molmil](/molmil-images/mine/8om9) | MutSbeta bound to (CAG)2 DNA (open form) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | MutSbeta bound to (CAG)2 DNA (open form) To Be Published
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8A49
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![BU of 8a49 by Molmil](/molmil-images/mine/8a49) | Endoglycosidase S in complex with IgG1 Fc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc, Secreted endoglycosidase EndoS | 著者 | Sudol, A.S.L, Tews, I, Crispin, M. | 登録日 | 2022-06-10 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS. Nat Commun, 13, 2022
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