PDB: 10140 件ウェブページステータス検索Chemie searchBIRD

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6O3G	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41). 分子名称: GLYCEROL, MEPER peptide, region 671-683 of HIV-1 gp41, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.645 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
5FEH	Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody 分子名称: 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ... 著者 Murrell, S, Wilson, I.A. 登録日 2015-12-17 公開日 2017-08-16 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity, 47, 2017
8IA6	Crystal structure of scFv antibody against Phospholipase A2 of Echis carinatus venom 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, scFv antibody 著者 Kumar, A, Madni, Z.K, Salunke, D.M. 登録日 2023-02-07 公開日 2024-02-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of scFv antibody against Phospholipase A2 of Echis carinatus venom To Be Published
4AMK	Fab fragment of antiporphrin antibody 13g10 分子名称: FAB13G10, HEAVY CHAIN, LIGHT CHAIN, ... 著者 Mahy, J.P, Golinelli-Pimpaneau, B. 登録日 2012-03-12 公開日 2012-10-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of Two Anti-Porphyrin Antibodies with Peroxidase Activity. Plos One, 7, 2012
4AT6	Fab fragment of antiporphyrin antibody 14H7 分子名称: FAB 14H7 HEAVY CHAIN, FAB 14H7 LIGHT CHAIN 著者 Golinelli-Pimpaneau, B, Mahy, J.P. 登録日 2012-05-04 公開日 2012-10-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.549 Å) 主引用文献 Crystal Structure of Two Anti-Porphyrin Antibodies with Peroxidase Activity. Plos One, 7, 2012
6OKP	B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 分子名称: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2019-04-14 公開日 2019-06-05 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
6WEZ	Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ... 著者 Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. 登録日 2020-04-03 公開日 2020-11-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun, 12, 2021
6WF0	Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A. 登録日 2020-04-03 公開日 2020-11-25 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun, 12, 2021
4PLJ	Hepatitis E Virus E2s domain (Genotype IV) in complex with a neutralizing antibody 8G12 分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein 著者 Tang, X.H, Li, S.W, Sivaraman, J. 登録日 2014-05-18 公開日 2015-04-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody Cell Res., 25, 2015
4POU	VHH-metal in Complex with RNase A 分子名称: Ribonuclease pancreatic, VHH Antibody 著者 Fanning, S.W, Walter, R, Horn, J.R. 登録日 2014-02-26 公開日 2014-09-24 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site. Protein Eng.Des.Sel., 27, 2014
7E3O	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody nCoV617 分子名称: Spike protein S1, nCoV617 Heigh Chain, nCoV617 Light Chain 著者 Chen, S.D, Yang, M. 登録日 2021-02-09 公開日 2021-09-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural Basis of a Human Neutralizing Antibody Specific to the SARS-CoV-2 Spike Protein Receptor-Binding Domain. Microbiol Spectr, 9, 2021
6O3K	Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 分子名称: GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6O3U	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-27 公開日 2019-12-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.105 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
7SI2	Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD) 分子名称: 10-28 Heavy Chain, 10-28 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Reddem, E.R, Shapiro, L. 登録日 2021-10-12 公開日 2022-04-27 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
7SD5	Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain 分子名称: 10-40 Heavy chain, 10-40 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Reddem, E.R, Casner, R.G, Shapiro, L. 登録日 2021-09-29 公開日 2022-04-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
6O3D	Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1. 分子名称: GLYCEROL, PGZL1 FAB HEAVY CHAIN, PGZL1 FAB LIGHT CHAIN, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.402 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
6O3J	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA) 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.416 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
8TOX	Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... 著者 Wang, S, Kwong, P.D. 登録日 2023-08-04 公開日 2024-08-14 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab To Be Published
6O3L	Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41). 分子名称: GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ... 著者 Irimia, A, Wilson, I.A. 登録日 2019-02-26 公開日 2019-12-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
4PLK	Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12 分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein 著者 Tang, X.H, Li, S.W, Sivaraman, J. 登録日 2014-05-18 公開日 2015-04-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody Cell Res., 25, 2015
6DB7	Crystal structure of anti-HIV-1 V3 Fab 1334 in complex with a HIV-1 gp120 V3 peptide from MN strain 分子名称: GLYCEROL, HIV-1 gp120 V3 peptide from MN strain, Human monoclonal anti-HIV-1 gp120 V3 antibody 1334 Fab heavy chain, ... 著者 Chan, K.-W, Kong, X.-P. 登録日 2018-05-02 公開日 2018-07-11 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.213 Å) 主引用文献 Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection. J. Virol., 92, 2018
6EAY	Structural Basis for Broad Neutralization of Ebolaviruses by an Antibody Targeting the Glycoprotein Fusion Loop 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CA45 heavy chain, CA45 light chain, ... 著者 Janus, B.M, Ofek, G. 登録日 2018-08-03 公開日 2018-10-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.72 Å) 主引用文献 Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop. Nat Commun, 9, 2018
4N1H	Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis 分子名称: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N 著者 Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. 登録日 2013-10-04 公開日 2014-10-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
4OD2	Crystal structure of the Fab fragment of an anti-DR5 antibody bound to DR5 分子名称: Fab fragment of drozitumab, heavy chain, light chain, ... 著者 Hymowitz, S.G, Compaan, D. 登録日 2014-01-09 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ., 15, 2008
8C89	SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab) 分子名称: 17T2 Fab heavy chain, 17T2 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Modrego, A, Carlero, D, Bueno-Carrasco, M.T, Santiago, C, Carolis, C, Arranz, R, Blanco, J, Magri, G. 登録日 2023-01-19 公開日 2024-01-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.41 Å) 主引用文献 A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity. Nat Commun, 15, 2024

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