1S0U
 
 | | eIF2gamma apo | | 分子名称: | Translation initiation factor 2 gamma subunit, ZINC ION | | 著者 | Roll-Mecak, A, Alone, P, Cao, C, Dever, T.E, Burley, S.K. | | 登録日 | 2004-01-04 | | 公開日 | 2004-01-20 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray Structure of Translation Initiation Factor eIF2gamma: IMPLICATIONS FOR tRNA AND eIF2alpha BINDING.
J.Biol.Chem., 279, 2004
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1S0V
 | | Structural basis for substrate selection by T7 RNA polymerase | | 分子名称: | 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... | | 著者 | Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-01-05 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for substrate selection by t7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
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1S0W
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1S0X
 | | Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A | | 分子名称: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Nuclear receptor ROR-alpha | | 著者 | Kallen, J, Schlaeppi, J.M, Bitsch, F, Delhon, I, Fournier, B. | | 登録日 | 2004-01-05 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A
J.Biol.Chem., 279, 2004
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1S0Y
 | | The structure of trans-3-chloroacrylic acid dehalogenase, covalently inactivated by the mechanism-based inhibitor 3-bromopropiolate at 2.3 Angstrom resolution | | 分子名称: | MALONIC ACID, alpha-subunit of trans-3-chloroacrylic acid dehalogenase, beta-subunit of trans-3-chloroacrylic acid dehalogenase | | 著者 | de Jong, R.M, Brugman, W, Poelarends, G.J, Whitman, C.P, Dijkstra, B.W. | | 登録日 | 2004-01-05 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily
J.Biol.Chem., 279, 2004
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1S0Z
 | | Crystal structure of the VDR LBD complexed to seocalcitol. | | 分子名称: | SEOCALCITOL, Vitamin D3 receptor | | 著者 | Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. | | 登録日 | 2004-01-05 | | 公開日 | 2004-04-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
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1S10
 | | Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | | 著者 | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | 登録日 | 2004-01-05 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.
Mol.Cell, 13, 2004
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1S12
 | | Crystal structure of TM1457 | | 分子名称: | ACETATE ION, hypothetical protein TM1457 | | 著者 | Shin, D.H, Lou, Y, Jancarik, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2004-01-05 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of TM1457 from Thermotoga maritima.
J.Struct.Biol., 152, 2005
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1S13
 | | Human Heme Oxygenase Oxidatition of alpha- and gamma-meso-Phenylhemes | | 分子名称: | 2-PHENYLHEME, Heme oxygenase 1 | | 著者 | Wang, J, Niemevz, F, Lad, L, Buldain, G, Poulos, T.L, Ortiz de Montellano, P.R. | | 登録日 | 2004-01-05 | | 公開日 | 2004-08-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Human heme oxygenase oxidation of 5- and 15-phenylhemes.
J.Biol.Chem., 279, 2004
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1S14
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1S16
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1S17
 | | Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors | | 分子名称: | 2-(3,4-DIHYDRO-3-OXO-2H-BENZO[B][1,4]THIAZIN-2-YL)-N-HYDROXYACETAMIDE, GLYCEROL, NICKEL (II) ION, ... | | 著者 | Molteni, V, He, X, Nabakka, J, Yang, K, Kreusch, A, Gordon, P, Bursulaya, B, Ryder, N.S, Goldberg, R, He, Y. | | 登録日 | 2004-01-05 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of novel potent bicyclic peptide deformylase inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
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1S18
 | | Structure and protein design of human apyrase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. | | 登録日 | 2004-01-05 | | 公開日 | 2004-03-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and protein design of a human platelet function inhibitor.
Cell(Cambridge,Mass.), 116, 2004
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1S19
 | | Crystal structure of VDR ligand binding domain complexed to calcipotriol. | | 分子名称: | CALCIPOTRIOL, Vitamin D3 receptor | | 著者 | Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. | | 登録日 | 2004-01-06 | | 公開日 | 2004-04-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
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1S1A
 | | Pterocarpus angolensis seed lectin (PAL) with one binding site free and one binding site containing the disaccharide Man(a1-3)ManMe | | 分子名称: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | | 著者 | Buts, L, Imberty, A, Wyns, L, Beeckmans, S, Loris, R. | | 登録日 | 2004-01-06 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 |
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1S1C
 | | Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ... | | 著者 | Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R. | | 登録日 | 2004-01-06 | | 公開日 | 2004-02-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.
J.Biol.Chem., 279, 2004
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1S1D
 | | Structure and protein design of human apyrase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. | | 登録日 | 2004-01-06 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure and protein design of a human platelet function inhibitor.
Cell(Cambridge,Mass.), 116, 2004
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1S1E
 | | Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1) | | 分子名称: | CALCIUM ION, Kv channel interacting protein 1 | | 著者 | Scannevin, R.H, Wang, K.-W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.-X, Xu, Z.-B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | | 登録日 | 2004-01-06 | | 公開日 | 2005-01-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.
Neuron, 41, 2004
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1S1F
 | | Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways | | 分子名称: | 4-PHENYL-1H-IMIDAZOLE, GLYCEROL, MALONIC ACID, ... | | 著者 | Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R. | | 登録日 | 2004-01-06 | | 公開日 | 2005-01-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J.Biol.Chem., 280, 2005
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1S1G
 | | Crystal Structure of Kv4.3 T1 Domain | | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | | 登録日 | 2004-01-06 | | 公開日 | 2004-03-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.
Neuron, 41, 2004
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1S1J
 | | Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1 | | 分子名称: | (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one, Cell division protein zipA | | 著者 | Jenning, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenney, C.H, Moghazeh, S.L, Peterson, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G. | | 登録日 | 2004-01-06 | | 公開日 | 2004-05-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
Bioorg.Med.Chem.Lett., 14, 2004
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1S1K
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1S1L
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1S1M
 | | Crystal Structure of E. Coli CTP Synthetase | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, IODIDE ION, ... | | 著者 | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | | 登録日 | 2004-01-06 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Escherichia coli Cytidine Triphosphate Synthetase, a Nucleotide-Regulated Glutamine Amidotransferase/ATP-Dependent Amidoligase Fusion Protein and Homologue of Anticancer and Antiparasitic Drug Targets
Biochemistry, 43, 2004
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1S1N
 | | SH3 domain of human nephrocystin | | 分子名称: | Nephrocystin 1 | | 著者 | Le Maire, A, Weber, T, Saunier, S, Antignac, C, Ducruix, A, Dardel, F. | | 登録日 | 2004-01-07 | | 公開日 | 2005-01-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis.
Proteins, 59, 2005
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