Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5OJQ
DownloadVisualize
BU of 5ojq by Molmil
The modeled structure of of wild type extended type VI secretion system sheath/tube complex in vibrio cholerae based on cryo-EM reconstruction of the non-contractile sheath/tube complex
分子名称: Haemolysin co-regulated protein, Type VI secretion protein, VipA
著者Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M.
登録日2017-07-22
公開日2017-08-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
5NZT
DownloadVisualize
BU of 5nzt by Molmil
The structure of the COPI coat linkage I
分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
著者Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
登録日2017-05-15
公開日2017-06-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5OLC
DownloadVisualize
BU of 5olc by Molmil
Crystal structure of the 3,6-anhydro-D-galactonate cycloisomerase from Zobellia galactanivorans
分子名称: Galactonate dehydratase, MAGNESIUM ION
著者Michel, G, Czjzek, M, Jam, M.
登録日2017-07-27
公開日2017-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria.
Nat Commun, 8, 2017
5NWT
DownloadVisualize
BU of 5nwt by Molmil
Crystal Structure of Escherichia coli RNA polymerase - Sigma54 Holoenzyme complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhang, X, Buck, M, Darbari, V.C, Yang, Y, Zhang, N, Lu, D, Glyde, R, Wang, Y, Winkelman, J, Gourse, R.L, Murakami, K.S.
登録日2017-05-08
公開日2017-09-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.76 Å)
主引用文献TRANSCRIPTION. Structures of the RNA polymerase-Sigma54 reveal new and conserved regulatory strategies.
Science, 349, 2015
2VDY
DownloadVisualize
BU of 2vdy by Molmil
Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN
著者Zhou, A, Wei, Z, Read, R.J.
登録日2007-10-13
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
5NZV
DownloadVisualize
BU of 5nzv by Molmil
The structure of the COPI coat linkage IV
分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
著者Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
登録日2017-05-15
公開日2017-06-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (17.299999 Å)
主引用文献9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5O5O
DownloadVisualize
BU of 5o5o by Molmil
X-ray crystal structure of RapZ from Escherichia coli (P32 space group)
分子名称: RNase adapter protein RapZ, SULFATE ION
著者Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F.
登録日2017-06-02
公開日2017-08-30
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.404 Å)
主引用文献Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
5O3K
DownloadVisualize
BU of 5o3k by Molmil
Crystal Structure of mutant M54L/M64L/M96L of Two-Domain Laccase from Streptomyces griseoflavus with 1 mM copper sulfate on growth medium
分子名称: COPPER (II) ION, GLYCEROL, OXYGEN ATOM, ...
著者Gabdulkhakov, A.G, Tishchenko, T.V.
登録日2017-05-24
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Incorporation of Copper Ions into T2/T3 Centers of Two-Domain Laccases.
Mol.Biol.(Moscow), 52, 2018
5O03
DownloadVisualize
BU of 5o03 by Molmil
GII.10 Vietnam 026 protruding domain in complex with Nanobody Nano-32
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Koromyslova, A.D, Hansman, G.H.
登録日2017-05-16
公開日2017-10-04
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization.
PLoS Pathog., 13, 2017
5PHK
DownloadVisualize
BU of 5phk by Molmil
PanDDA analysis group deposition -- Crystal Structure of JMJD2D in complex with N09720a
分子名称: 1,2-ETHANEDIOL, BENZIMIDAZOLE, Lysine-specific demethylase 4D, ...
著者Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Szykowska, A, Burgess-Brown, N, Brennan, P.E, Cox, O, Oppermann, U, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
登録日2017-02-07
公開日2017-03-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5PHG
DownloadVisualize
BU of 5phg by Molmil
PanDDA analysis group deposition -- Crystal Structure of JMJD2D in complex with N09689a
分子名称: 1,2-ETHANEDIOL, 1-(4-fluorophenyl)thiourea, Lysine-specific demethylase 4D, ...
著者Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Szykowska, A, Burgess-Brown, N, Brennan, P.E, Cox, O, Oppermann, U, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
登録日2017-02-07
公開日2017-03-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.398 Å)
主引用文献A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5OP6
DownloadVisualize
BU of 5op6 by Molmil
Factor Inhibiting HIF (FIH) in complex with zinc and GSK128863
分子名称: 2-[[1,3-dicyclohexyl-4-oxidanyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Leissing, T.M, Schofield, C.J, Clifton, I.J, Thinnes, C.C, Lu, X.
登録日2017-08-09
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017
5OSB
DownloadVisualize
BU of 5osb by Molmil
GLIC-GABAAR alpha1 chimera crystallized in complex with THDOC at pH4.5
分子名称: ACETATE ION, CHLORIDE ION, Proton-gated ion channel,Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, ...
著者Laverty, D.C, Gold, M.G, Smart, T.G.
登録日2017-08-17
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites.
Nat. Struct. Mol. Biol., 24, 2017
5OPC
DownloadVisualize
BU of 5opc by Molmil
Factor Inhibiting HIF (FIH) in complex with zinc and Vadadustat
分子名称: GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ...
著者Leissing, T.M, Schofield, C.J, Clifton, I.J, Lu, X, Zhang, D.
登録日2017-08-09
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017
5OFO
DownloadVisualize
BU of 5ofo by Molmil
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein
分子名称: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R.
登録日2017-07-11
公開日2017-08-16
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Sci Adv, 3, 2017
5OHE
DownloadVisualize
BU of 5ohe by Molmil
Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide
分子名称: CHLORIDE ION, CYANIDE ION, Globin-coupled histidine kinase, ...
著者Skalova, T, Kolenko, P, Dohnalek, J, Stranava, M, Martinkova, M.
登録日2017-07-16
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction.
J. Biol. Chem., 292, 2017
5OHJ
DownloadVisualize
BU of 5ohj by Molmil
Human phosphodiesterase 4B catalytic domain in complex with a pyrrolidinyl inhibitor.
分子名称: MAGNESIUM ION, ZINC ION, [(1~{S})-2-[3,5-bis(chloranyl)-1-oxidanyl-pyridin-1-ium-4-yl]-1-[4-[bis(fluoranyl)methoxy]-3-(cyclopropylmethoxy)phenyl]ethyl] (2~{S})-1-[3-(dimethylcarbamoyl)phenyl]sulfonylpyrrolidine-2-carboxylate, ...
著者Rizzi, A, Carzaniga, L, Armani, E.
登録日2017-07-17
公開日2017-12-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Optimization of Thiazolidinyl and Pyrrolidinyl Derivatives as Inhaled PDE4 Inhibitors for Respiratory Diseases.
J. Med. Chem., 60, 2017
5Q0U
DownloadVisualize
BU of 5q0u by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3, trans-4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)cyclohexyl hydrogen sulfate
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q0O
DownloadVisualize
BU of 5q0o by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: (2S)-2-{2-[4-(benzenecarbonyl)phenyl]-1H-benzimidazol-1-yl}-N,2-dicyclohexylacetamide, Bile acid receptor, CHLORIDE ION, ...
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q14
DownloadVisualize
BU of 5q14 by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: 4-{(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylethoxy}-3-fluorobenzoic acid, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q1C
DownloadVisualize
BU of 5q1c by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: (2S)-2-cyclohexyl-2-[2-(2,6-dimethoxypyridin-3-yl)-5,6-difluoro-1H-benzimidazol-1-yl]-N-(trans-4-hydroxycyclohexyl)acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q0L
DownloadVisualize
BU of 5q0l by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: (2S)-N,2-dicyclohexyl-2-{2-[4-(hydroxymethyl)phenyl]-1H-benzimidazol-1-yl}acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q0Y
DownloadVisualize
BU of 5q0y by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: (2S)-N,2-dicyclohexyl-2-{5,6-difluoro-2-[6-(1H-pyrazol-1-yl)pyridin-3-yl]-1H-benzimidazol-1-yl}acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5Q1F
DownloadVisualize
BU of 5q1f by Molmil
Ligand binding to FARNESOID-X-RECEPTOR
分子名称: Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3, trans-4-({(2S)-2-cyclohexyl-2-[2-(2,6-dimethoxypyridin-3-yl)-5-fluoro-1H-benzimidazol-1-yl]acetyl}amino)cyclohexane-1-carboxylic acid
著者Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K.
登録日2017-05-31
公開日2017-07-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.
J. Comput. Aided Mol. Des., 32, 2018
5OP8
DownloadVisualize
BU of 5op8 by Molmil
Factor Inhibiting HIF (FIH) in complex with zinc and Molidustat
分子名称: 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)-1~{H}-pyrazol-3-one, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Leissing, T.M, Schofield, C.J, Clifton, I.J, Lu, X.
登録日2017-08-09
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017

223790

件を2024-08-14に公開中

PDB statisticsPDBj update infoContact PDBjnumon