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1TED
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Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis
分子名称: MYRISTIC ACID, pks18
著者Sankaranarayanan, R, Shanmugam, V.M, Rukmini, R.
登録日2004-05-25
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites
Nat.Struct.Mol.Biol., 11, 2004
1RWL
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BU of 1rwl by Molmil
Extracellular domain of Mycobacterium tuberculosis PknD
分子名称: CADMIUM ION, Serine/threonine-protein kinase pknD
著者Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2003-12-16
公開日2004-04-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller.
J.Mol.Biol., 339, 2004
1RWI
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BU of 1rwi by Molmil
Extracellular domain of Mycobacterium tuberculosis PknD
分子名称: CADMIUM ION, Serine/threonine-protein kinase pknD
著者Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2003-12-16
公開日2004-04-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller.
J.Mol.Biol., 339, 2004
3QHX
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BU of 3qhx by Molmil
Crystal Structure of Cystathionine gamma-synthase MetB (Cgs) from Mycobacterium ulcerans Agy99 bound to HEPES
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cystathionine gamma-synthase MetB (Cgs), GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-01-26
公開日2011-03-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans
Acta Crystallogr.,Sect.F, 67, 2011
1U2Q
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Crystal structure of Mycobacterium tuberculosis Low Molecular Weight Protein Tyrosine Phosphatase (MPtpA) at 2.5A resolution with glycerol in the active site
分子名称: CHLORIDE ION, GLYCEROL, low molecular weight protein-tyrosine-phosphatase
著者Madhurantakam, C, Rajakumara, E, Mazumdar, P.A, Saha, B, Mitra, D, Wiker, H.G, Sankaranarayanan, R, Das, A.K.
登録日2004-07-20
公開日2005-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Low-Molecular-Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis at 1.9-A Resolution
J.Bacteriol., 187, 2005
1U2P
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Crystal structure of Mycobacterium tuberculosis Low Molecular Protein Tyrosine Phosphatase (MPtpA) at 1.9A resolution
分子名称: CHLORIDE ION, low molecular weight protein-tyrosine-phosphatase
著者Madhurantakam, C, Rajakumara, E, Mazumdar, P.A, Saha, B, Mitra, D, Wiker, H.G, Sankaranarayanan, R, Das, A.K.
登録日2004-07-20
公開日2005-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Low-Molecular-Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis at 1.9-A Resolution
J.Bacteriol., 187, 2005
7CAE
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BU of 7cae by Molmil
Mycobacterium smegmatis LpqY-SugABC complex in the resting state
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z.
登録日2020-06-08
公開日2020-12-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
3T5C
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Crystal structure of N-terminal domain of FACL13 from Mycobacterium tuberculosis in different space group C2
分子名称: PROBABLE CHAIN-FATTY-ACID-CoA LIGASE FADD13
著者Goyal, A, Sankaranarayanan, R.
登録日2011-07-27
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Molecular basis of the functional divergence of fatty acyl-AMP ligase biosynthetic enzymes of Mycobacterium tuberculosis.
J.Mol.Biol., 416, 2012
7D5I
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Structure of Mycobacterium smegmatis bd complex in the apo-form.
分子名称: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ...
著者Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z.
登録日2020-09-26
公開日2021-06-23
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels.
Nat Commun, 12, 2021
3HUG
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BU of 3hug by Molmil
Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL
分子名称: PROBABLE CONSERVED MEMBRANE PROTEIN, RNA polymerase sigma factor, SULFATE ION, ...
著者Thakur, K.G, Gopal, B.
登録日2009-06-14
公開日2010-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA
J.Mol.Biol., 397, 2010
3T5B
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BU of 3t5b by Molmil
Crystal structure of N-terminal domain of FACL13 from Mycobacterium tuberculosis
分子名称: PROBABLE CHAIN-FATTY-ACID-CoA LIGASE FADD13
著者Goyal, A, Sankaranarayanan, R.
登録日2011-07-27
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular basis of the functional divergence of fatty acyl-AMP ligase biosynthetic enzymes of Mycobacterium tuberculosis.
J.Mol.Biol., 416, 2012
1TPY
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BU of 1tpy by Molmil
Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis
分子名称: CARBONATE ION, CETYL-TRIMETHYL-AMMONIUM, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Smith, C.V, Sacchettini, J.C.
登録日2004-06-16
公開日2004-10-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis
To be Published
1G2O
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BU of 1g2o by Molmil
CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PHOSPHATE ION, PURINE NUCLEOSIDE PHOSPHORYLASE
著者Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L.
登録日2000-10-20
公開日2001-08-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
7BGG
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BU of 7bgg by Molmil
Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, heterocyclic toxin methyltransferase (Rv0560c)
著者Denkhaus, L, Sartor, P, Einsle, O, Gerhardt, S, Fetzner, S.
登録日2021-01-07
公開日2021-09-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis.
J.Struct.Biol., 213, 2021
4KXR
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BU of 4kxr by Molmil
Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer
分子名称: EspG5, PE25, PPE41
著者Korotkova, N, Creekmore, C.C, Korotkov, K.V.
登録日2013-05-27
公開日2014-05-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.
Mol.Microbiol., 94, 2014
3QI6
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BU of 3qi6 by Molmil
Crystal Structure of Cystathionine gamma-synthase MetB (Cgs) from Mycobacterium ulcerans Agy99
分子名称: 1,2-ETHANEDIOL, Cystathionine gamma-synthase MetB (Cgs), GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-01-26
公開日2011-03-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans
Acta Crystallogr.,Sect.F, 67, 2011
3KRD
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BU of 3krd by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with Fellutamide B
分子名称: (3R)-3-HYDROXYDODECANOIC ACID, Fellutamide B, Proteasome subunit alpha, ...
著者Li, D, Li, H.
登録日2009-11-18
公開日2010-09-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome.
Arch.Biochem.Biophys., 501, 2010
3FAV
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BU of 3fav by Molmil
Structure of the CFP10-ESAT6 complex from Mycobacterium tuberculosis
分子名称: 6 kDa early secretory antigenic target, ESAT-6-like protein esxB, IMIDAZOLE, ...
著者Poulsen, C, Holton, S.J, Wilmanns, M, Song, Y.H.
登録日2008-11-18
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern.
Plos One, 9, 2014
3S0Q
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Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis, catalytic site mutant (Cys383Ala) at 1.45 resolution
分子名称: INVASION PROTEIN
著者Both, D, Schnell, R, Schneider, G.
登録日2011-05-13
公開日2011-08-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
8SWL
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BU of 8swl by Molmil
Substrate free structure of cytochrome P450 CYP105Q4 from mycobacterium marinum
分子名称: Cytochrome P450 105Q4 Cyp105Q4, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL
著者Mohamed, H.A, Bruning, J.B, Bell, S.G.
登録日2023-05-19
公開日2024-03-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum.
Arch.Biochem.Biophys., 754, 2024
3JZ6
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BU of 3jz6 by Molmil
Crystal structure of Mycobacterium smegmatis Branched Chain Aminotransferase in complex with pyridoxal-5'-phosphate at 1.9 angstrom.
分子名称: Branched-chain amino acid aminotransferase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
著者Castell, A, Mille, C, Unge, T.
登録日2009-09-23
公開日2010-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.
Acta Crystallogr.,Sect.D, 66, 2010
3IX2
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CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ACYCLOVIR
分子名称: 9-HYROXYETHOXYMETHYLGUANINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者de Azevedo Jr, W.F, Basso, L.A, Santos, D.S.
登録日2009-09-03
公開日2021-07-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir.
Biochimie, 94, 2012
8UZH
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SUMO fused Trehalose Synthase (TreS) of Mycobacterium tuberculosis
分子名称: CALCIUM ION, SUMO fused Trehalose Synthase (TreS),Trehalose synthase/amylase TreS
著者Pathirage, R, Ronning, D.R.
登録日2023-11-15
公開日2024-03-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
8UQV
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Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound
分子名称: 6-azido-6-deoxy-alpha-D-glucopyranose, CALCIUM ION, Trehalose synthase/amylase TreS, ...
著者Pathirage, R, Ronning, D.R.
登録日2023-10-24
公開日2024-03-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
7Y0D
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Cryo-EM structure of the Mycobacterium smegmatis DNA integrity scanning protein (MsDisA).
分子名称: DNA integrity scanning protein DisA
著者Gautam, S, Vinothkumar, K.R, Chatterji, D.
登録日2022-06-04
公開日2023-02-08
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Regulatory mechanisms of c-di-AMP synthase (MsDisA) protein from Mycobacterium smegmatis revealed by a structure - function analysis.
Protein Sci., 32, 2023

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