5NYJ
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1LF4
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![BU of 1lf4 by Molmil](/molmil-images/mine/1lf4) | STRUCTURE OF PLASMEPSIN II | 分子名称: | Plasmepsin 2 | 著者 | Asojo, O.A, Gulnik, S.V, Afonina, E, Yu, B, Ellman, J.A, Haque, T.S, Silva, A.M. | 登録日 | 2002-04-10 | 公開日 | 2002-10-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum. J.Mol.Biol., 327, 2003
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8OFB
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![BU of 8ofb by Molmil](/molmil-images/mine/8ofb) | Crystal Structure of T. maritima reverse gyrase with a minimal latch, hexagonal form | 分子名称: | CHLORIDE ION, HEXAETHYLENE GLYCOL, Reverse gyrase, ... | 著者 | Klostermeier, D, Rasche, R, Mhaindarkar, V, Kummel, D, Rudolph, M.G. | 登録日 | 2023-03-15 | 公開日 | 2023-04-26 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain. Acta Crystallogr D Struct Biol, 79, 2023
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5YZI
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5UL0
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![BU of 5ul0 by Molmil](/molmil-images/mine/5ul0) | S. CEREVISIAE CYP51 COMPLEXED WITH VT-1161 | 分子名称: | (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, Lanosterol 14-alpha demethylase, PENTAETHYLENE GLYCOL, ... | 著者 | Tyndall, J.D, Keniya, M.V, Sabherwal, M, Monk, B.C. | 登録日 | 2017-01-23 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161. Antimicrob.Agents Chemother., 63, 2019
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5O1W
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5ULG
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5Z18
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5Z1B
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5LU2
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![BU of 5lu2 by Molmil](/molmil-images/mine/5lu2) | Human 14-3-3 sigma complexed with long HSPB6 phosphopeptide | 分子名称: | 14-3-3 protein sigma, Heat shock protein beta-6 | 著者 | Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V. | 登録日 | 2016-09-07 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator. Structure, 25, 2017
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5UYS
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![BU of 5uys by Molmil](/molmil-images/mine/5uys) | Human steroidogenic cytochrome P450 17A1 with 3alphaOH-5alpha-abiraterone analog | 分子名称: | (3alpha,5alpha,8alpha)-17-(pyridin-3-yl)androst-16-en-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase | 著者 | Scott, E.E, Petrunak, E.M. | 登録日 | 2017-02-24 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.392 Å) | 主引用文献 | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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5V05
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![BU of 5v05 by Molmil](/molmil-images/mine/5v05) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (rIII) | 分子名称: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | 著者 | Shi, Y, Beese, L.S. | 登録日 | 2017-02-28 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UOG
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![BU of 5uog by Molmil](/molmil-images/mine/5uog) | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in apo form | 分子名称: | NADPH-dependent glyoxylate/hydroxypyruvate reductase, SULFATE ION | 著者 | Shabalin, I.G, Handing, K.B, Gasiorowska, O.A, Cooper, D.R, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2017-01-31 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57, 2018
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5Z5F
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![BU of 5z5f by Molmil](/molmil-images/mine/5z5f) | Crystal structure of a thermostable glycoside hydrolase family 43 {beta}-1,4-xylosidase from Geobacillus thermoleovorans IT-08 in complex with L-arabinose | 分子名称: | Beta-xylosidase, CALCIUM ION, beta-L-arabinofuranose | 著者 | Rohman, A, van Oosterwijk, N, Puspaningsih, N.N.T, Dijkstra, B.W. | 登録日 | 2018-01-18 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of product inhibition by arabinose and xylose of the thermostable GH43 beta-1,4-xylosidase from Geobacillus thermoleovorans IT-08. PLoS ONE, 13, 2018
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5V0D
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![BU of 5v0d by Molmil](/molmil-images/mine/5v0d) | Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f2II) | 分子名称: | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... | 著者 | Shi, Y, Beese, L.S. | 登録日 | 2017-02-28 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8RUS
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![BU of 8rus by Molmil](/molmil-images/mine/8rus) | Hen egg-white lysozyme (HEWL) structure from EuXFEL FXE, multi-hit Droplet-on-Demand (DoD) injection, 9.3 keV photon energy, space group P432121 | 分子名称: | ACETATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Perrett, S, van Thor, J.J. | 登録日 | 2024-01-31 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Kilohertz droplet-on-demand serial femtosecond crystallography at the European XFEL station FXE. Struct Dyn., 11, 2024
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5UQC
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![BU of 5uqc by Molmil](/molmil-images/mine/5uqc) | Crystal structure of mouse CRMP2 | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2 | 著者 | Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L. | 登録日 | 2017-02-07 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Channels (Austin), 11, 2017
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5Z7O
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![BU of 5z7o by Molmil](/molmil-images/mine/5z7o) | SmChiA sliding-intermediate with chitotetraose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase A, GLYCEROL | 著者 | Nakamura, A, Iino, R. | 登録日 | 2018-01-30 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Processive chitinase is Brownian monorail operated by fast catalysis after peeling rail from crystalline chitin. Nat Commun, 9, 2018
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5LK3
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7LES
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5ZF4
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![BU of 5zf4 by Molmil](/molmil-images/mine/5zf4) | Structure of human dihydroorotate dehydrogenase in complex with 275-10-COOMe | 分子名称: | ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Miyazaki, Y, Inaoka, K.D, Shiba, T, Saimoto, H, Amalia, E, Kido, Y, Sakai, C, Nakamura, M, Moore, L.A, Harada, S, Kita, K. | 登録日 | 2018-03-02 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions. Front Pharmacol, 9, 2018
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1CGE
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![BU of 1cge by Molmil](/molmil-images/mine/1cge) | CRYSTAL STRUCTURES OF RECOMBINANT 19-KDA HUMAN FIBROBLAST COLLAGENASE COMPLEXED TO ITSELF | 分子名称: | CALCIUM ION, FIBROBLAST COLLAGENASE, ZINC ION | 著者 | Lovejoy, B, Hassell, A.M, Luther, M.A, Weigl, D, Jordan, S.R. | 登録日 | 1994-02-03 | 公開日 | 1995-03-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself. Biochemistry, 33, 1994
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8E8O
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![BU of 8e8o by Molmil](/molmil-images/mine/8e8o) | Cryo-EM structure of human ME3 in the presence of citrate | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, mitochondrial | 著者 | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | 登録日 | 2022-08-25 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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5ZFA
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![BU of 5zfa by Molmil](/molmil-images/mine/5zfa) | Structure of human dihydroorotate dehydrogenase in complex with 287-12-OCOiPr | 分子名称: | (2E,6E)-8-(3-chloro-5-formyl-2,6-dihydroxy-4-methylphenyl)-3,6-dimethylocta-2,6-dien-1-yl 2-methylpropanoate, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Miyazaki, Y, Inaoka, K.D, Shiba, T, Saimoto, H, Amalia, E, Kido, Y, Sakai, C, Nakamura, M, Moore, L.A, Harada, S, Kita, K. | 登録日 | 2018-03-02 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Selective Cytotoxicity of Dihydroorotate Dehydrogenase Inhibitors to Human Cancer Cells Under Hypoxia and Nutrient-Deprived Conditions. Front Pharmacol, 9, 2018
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5UTR
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![BU of 5utr by Molmil](/molmil-images/mine/5utr) | Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane | 分子名称: | Beta-hexosaminidase, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]butanamide | 著者 | Vadlamani, G, Mark, B.L. | 登録日 | 2017-02-15 | 公開日 | 2017-04-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance. Protein Sci., 26, 2017
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