8Z10
 
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8WCN
 | | Cryo-EM structure of PAO1-ImcA with GMPCPP | | 分子名称: | Diguanylate cyclase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | 著者 | Zhan, X.L, Zhang, K, Wang, C.C, Fan, Q, Tang, X.J, Zhang, X, Wang, K, Fu, Y, Liang, H.H. | | 登録日 | 2023-09-13 | | 公開日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa.
Nat Commun, 15, 2024
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9BKL
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8VEN
 | | Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 in complex with cefoperazone | | 分子名称: | (2R,4R)-2-[(1R)-1-{[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5-methylidene-1,3-thiazinane-4-carboxylic acid, Probable peptidoglycan D,D-transpeptidase PenA | | 著者 | Stratton, C, Bala, S, Davies, C. | | 登録日 | 2023-12-20 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041.
Acs Infect Dis., 10, 2024
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9FX5
 | | Crystal structure of Cryo2RT Thaumatin at 296K | | 分子名称: | L(+)-TARTARIC ACID, Thaumatin I | | 著者 | Huang, C.Y, Aumonier, S, Olieric, V, Wang, M. | | 登録日 | 2024-07-01 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.592 Å) | | 主引用文献 | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals.
Acta Crystallogr D Struct Biol, 80, 2024
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8ZWH
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8Y2U
 | | Crystal structure of 3C protease from coxsackievirus B4 | | 分子名称: | Protease 3C | | 著者 | Jiang, H.H, Lin, C, Zhang, J, Li, J. | | 登録日 | 2024-01-27 | | 公開日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal structures of the 3C proteases from Coxsackievirus B3 and B4.
Acta Crystallogr.,Sect.F, 80, 2024
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8W9P
 | | Structure of full Banna virus | | 分子名称: | VP10, VP2, VP4, ... | | 著者 | Li, Z, Cao, S. | | 登録日 | 2023-09-05 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes.
Nat Commun, 15, 2024
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9FT0
 | | Yeast 20S proteasome in complex with epoxyketone inhibitor 42 | | 分子名称: | (2S)-N-[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]-2-(2-morpholin-4-ylethanoylamino)-4-oxidanyl-butanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | | 著者 | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | | 登録日 | 2024-06-23 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites
to be published
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8X70
 | | The Crystal Structure of IFI16 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, Gamma-interferon-inducible protein 16, ... | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Wang, J. | | 登録日 | 2023-11-22 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Crystal Structure of IFI16 from Biortus.
To Be Published
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8Z5J
 | | Beta-catenin Crystal Structure | | 分子名称: | Catenin beta-1 | | 著者 | Tim, F. | | 登録日 | 2024-04-18 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 67, 2024
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9B56
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8XFZ
 | | The structure of HLA-A/L1-2 | | 分子名称: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | | 著者 | Zhang, J.N, Yue, C, Liu, J. | | 登録日 | 2023-12-14 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
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8Y14
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8VJC
 | | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | | 登録日 | 2024-01-06 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
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8WWU
 | | 1-naphthylamine GS in complex with AMP PNP | | 分子名称: | Glutamine synthetase, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Zhang, S.T, Zhou, N.Y. | | 登録日 | 2023-10-26 | | 公開日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation
To Be Published
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9BHW
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9B5B
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8VAP
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6R6A
 | | Major aspartyl peptidase 1 from C. neoformans | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Endopeptidase, ... | | 著者 | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | | 登録日 | 2019-03-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
J.Med.Chem., 64, 2021
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8XAT
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8YF8
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8W9R
 | | Structure of Banna virus core | | 分子名称: | VP10, VP8, Vp2 | | 著者 | Li, Z, Cao, S. | | 登録日 | 2023-09-05 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes.
Nat Commun, 15, 2024
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8XDT
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8W6H
 | | NaS1 with sulfate - IN/IN state | | 分子名称: | CHOLESTEROL, SODIUM ION, SULFATE ION, ... | | 著者 | Chi, X, Chen, Y, Li, Y, Zhang, Y, Shen, Y, Chen, Y, Wang, Z, Yan, R. | | 登録日 | 2023-08-28 | | 公開日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism.
Sci Adv, 10, 2024
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