PDB: 242842 件ウェブページステータス検索Chemie searchBIRD

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8QBY	Respiratory complex I from Paracoccus denitrificans in MSP2N2 nanodiscs 分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... 著者 Ivanov, B.S, Bridges, H.R, Hirst, J. 登録日 2023-08-25 公開日 2024-09-11 最終更新日 2025-03-26 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structure of the turnover-ready state of an ancestral respiratory complex I. Nat Commun, 15, 2024
4EII	Unliganded E. cloacae R91K MurA 分子名称: 1,2-ETHANEDIOL, GLYCEROL, TRIETHYLENE GLYCOL, ... 著者 Han, H, Zhu, J.-Y, Schonbrunn, E. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Open-close transition of MurA To be Published
4YR7	Structure of LuxP In Complex With 1-deoxy-alpha-L-xylulofuranose-1,2-borate 分子名称: 1-deoxy-alpha-L-xylulofuranose-1,2-borate, Autoinducer 2-binding periplasmic protein LuxP 著者 McDonough, M.A, Sattin, S, Davis, B.G. 登録日 2015-03-14 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.533 Å) 主引用文献 Discovery of Glycomimetic Agonists from a Protocell Metabolism, Proto-natural Product Libraries To Be Published
1TGS	THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN PANCREATIC SECRETORY INHIBITOR (KAZAL TYPE) AND TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. STRUCTURE SOLUTION, CRYSTALLOGRAPHIC REFINEMENT AND PRELIMINARY STRUCTURAL INTERPRETATION 分子名称: CALCIUM ION, PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE), SULFATE ION, ... 著者 Bolognesi, M, Gatti, G, Menegatti, E, Guarneri, M, Marquart, M, Papamokos, E, Huber, R. 登録日 1982-09-27 公開日 1983-01-18 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation. J.Mol.Biol., 162, 1982
8HL7	Crystal structure of p97 N/D1 in complex with a valosin-containing protein methyltransferase 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Kang, W, Yang, J.K. 登録日 2022-11-29 公開日 2023-07-12 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase. Iscience, 26, 2023
1TRY	STRUCTURE OF INHIBITED TRYPSIN FROM FUSARIUM OXYSPORUM AT 1.55 ANGSTROMS 分子名称: ISOPROPYL ALCOHOL, PHOSPHORYLISOPROPANE, TRYPSIN 著者 Rypniewski, W.R, Dambmann, C, Von Der Osten, C, Dauter, M, Wilson, K.S. 登録日 1994-03-07 公開日 1996-01-01 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of inhibited trypsin from Fusarium oxysporum at 1.55 A. Acta Crystallogr.,Sect.D, 51, 1995
9D3V	CRYSTAL STRUCTURE OF EGFR(L858R/T790M/C797S) IN COMPLEX WITH AUR-3418 分子名称: (4S)-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-methyl-1-(propan-2-yl)-1H-imidazo[1,2-b]pyrazol-6-amine, CHLORIDE ION, Epidermal growth factor receptor 著者 Bell, J.A. 登録日 2024-08-12 公開日 2025-03-05 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform. J.Med.Chem., 67, 2024
4Y5A	Endothiapepsin in complex with fragment 206 分子名称: 1,2-ETHANEDIOL, 1-[5-(trifluoromethyl)furan-2-yl]methanamine, ACETATE ION, ... 著者 Ehrmann, F.R, Huschmann, F.U, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library To Be Published
6DXZ	Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL, 4-(2,4,4-trimethylpentan-2-yl)phenol, ... 著者 Gorelik, A, Gebai, A, Illes, K, Piomelli, D, Nagar, B. 登録日 2018-07-01 公開日 2018-09-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2NAP	DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Dias, J.M, Than, M, Humm, A, Huber, R, Bourenkov, G, Bartunik, H, Bursakov, S, Calvete, J, Caldeira, J, Carneiro, C, Moura, J, Moura, I, Romao, M.J. 登録日 1998-09-18 公開日 1999-09-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the first dissimilatory nitrate reductase at 1.9 A solved by MAD methods. Structure Fold.Des., 7, 1999
8QOC	Crystal structure of Staphylococcus aureus PLP Synthase (Pdx1) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ullah, N, Wrenger, C, Betzel, C. 登録日 2023-09-28 公開日 2024-10-02 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface. J.Biol.Chem., 300, 2024
1TRN	CRYSTAL STRUCTURE OF HUMAN TRYPSIN 1: UNEXPECTED PHOSPHORYLATION OF TYROSINE 151 分子名称: PHOSPHORYLISOPROPANE, TRYPSIN 著者 Gaboriaud, C, Fontecilla-Camps, J.C. 登録日 1995-03-16 公開日 1995-06-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151. J.Mol.Biol., 259, 1996
3H6U	Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS1493 at 1.85 A resolution 分子名称: (3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, CITRATE ANION, GLUTAMIC ACID, ... 著者 Hald, H, Gajhede, M, Kastrup, J.S. 登録日 2009-04-24 公開日 2009-07-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J.Mol.Biol., 391, 2009
4EUS	Crystal structure of the CFTR inhibitory factor Cif bound to 1,2-hexanediol 分子名称: (2S)-hexane-1,2-diol, Putative hydrolase 著者 Bahl, C.D, Madden, D.R. 登録日 2012-04-25 公開日 2013-08-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif. Biochemistry, 55, 2016
4MPW	Human beta-tryptase co-crystal structure with [(1,1,3,3-tetramethyldisiloxane-1,3-diyl)di-1-benzofuran-3,5-diyl]bis({4-[3-(aminomethyl)phenyl]piperidin-1-yl}methanone) 分子名称: ACETATE ION, CHLORIDE ION, TRIETHYLENE GLYCOL, ... 著者 White, A, Stein, A.J, Suto, R. 登録日 2013-09-13 公開日 2015-03-18 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Novel, Nonpeptidic, Orally Active Bivalent Inhibitor of Human beta-Tryptase. Pharmacology, 102, 2018
2N7Y	NMR structure of metal-binding domain 1 of ATP7B 分子名称: Copper-transporting ATPase 2 著者 Yu, C, Lee, W, Dmitriev, O. 登録日 2015-09-27 公開日 2016-09-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Structure of Metal Binding Domain 1 of the Copper Transporter ATP7B Reveals Mechanism of a Singular Wilson Disease Mutation. Sci Rep, 8, 2018
7AK6	Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Yin, Z, Bridges, H.R, Grba, D, Hirst, J. 登録日 2020-09-29 公開日 2021-02-03 最終更新日 2025-04-09 実験手法 ELECTRON MICROSCOPY (3.82 Å) 主引用文献 Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
4EB8	Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate 分子名称: 1,2-ETHANEDIOL, 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, ... 著者 Ho, M.C, Haapalainen, A.M, Suarez, J.J, Almo, S.C, Schramm, V.L. 登録日 2012-03-23 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography. Chem.Biol., 20, 2013
4YRR	Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)acetamide (Chem 1691) 分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, HISTIDINE, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-03-15 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4EHM	RabGGTase in complex with covalently bound Psoromic acid 分子名称: 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ... 著者 Guo, Z, Deraeve, C, Bon, R.S, Alexandrov, K, Waldmann, H, Wu, Y.W, Goody, R.S, Blankenfeldt, W. 登録日 2012-04-02 公開日 2012-05-30 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase J.Am.Chem.Soc., 134, 2012
7WWX	Crystal structure of Herbaspirillum huttiense L-arabinose 1-dehydrogenase (NAD bound form) 分子名称: DI(HYDROXYETHYL)ETHER, NAD(P)-dependent dehydrogenase (Short-subunit alcohol dehydrogenase family), NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Matsubara, R, Yoshiwara, K, Watanabe, Y, Watanabe, S. 登録日 2022-02-14 公開日 2022-03-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal structure of L-arabinose 1-dehydrogenase as a short-chain reductase/dehydrogenase protein. Biochem.Biophys.Res.Commun., 604, 2022
4EJ8	Apo HIV Protease (PR) dimer in closed form with fragment 1F1 in the outside/top of flap 分子名称: 1,2-ETHANEDIOL, 1H-indole-6-carboxylic acid, DIMETHYL SULFOXIDE, ... 著者 Tiefenbrunn, T, Stout, C.D. 登録日 2012-04-06 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.347 Å) 主引用文献 Small molecule regulation of protein conformation by binding in the Flap of HIV protease. Acs Chem.Biol., 8, 2013
9CK2	Human PU.1 minimal ETS Domain (165-258) bound to d(AATAAGCGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Poon, G.M.K. 登録日 2024-07-08 公開日 2025-05-21 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Human PU.1 minimal ETS Domain (165-258) bound to d(AATAAGCGGAAGTGGG) To Be Published
9KYG	Crystal structure of E.coli ac4C amidohydrolase YqfB in complex with cytidine 分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, MAGNESIUM ION, N(4)-acetylcytidine amidohydrolase 著者 Guo, W.T, Meng, C.Y, Wen, Y, Wu, B.X. 登録日 2024-12-09 公開日 2025-08-20 最終更新日 2025-09-24 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structural analysis of ASCH domain-containing proteins and their implications for nucleotide processing. Structure, 2025
1TMN	Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases 分子名称: CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ... 著者 Monzingo, A.F, Matthews, B.W. 登録日 1987-06-29 公開日 1989-01-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases Biochemistry, 23, 1984

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