2LY8
 
 | | The budding yeast chaperone Scm3 recognizes the partially unfolded dimer of the centromere-specific Cse4/H4 histone variant | | 分子名称: | Budding yeast chaperone Scm3 | | 著者 | Hong, J, Feng, H, Zhou, Z, Ghirlando, R, Bai, Y. | | 登録日 | 2012-09-13 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 Complex.
J.Mol.Biol., 425, 2013
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2BKC
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2BJY
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2XBJ
 | | Crystal Structure of Chk2 in complex with an inhibitor | | 分子名称: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Anderson, V.E, Walton, M.I, Eve, P.D, Caldwell, J.J, Pearl, L.H, Oliver, A.W, Collins, I, Garrett, M.D. | | 登録日 | 2010-04-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
J.Med.Chem., 54, 2011
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2C0W
 | | Molecular Structure of fd Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction | | 分子名称: | COAT PROTEIN B | | 著者 | Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K. | | 登録日 | 2005-09-08 | | 公開日 | 2005-12-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | FIBER DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane.
J.Mol.Biol., 355, 2006
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4BLU
 | | Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Punekar, A.S, Liljeruhm, J, Shepherd, T.R, Forster, A.C, Selmer, M. | | 登録日 | 2013-05-04 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Nucleic Acids Res., 41, 2013
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3ISM
 | | Crystal structure of the EndoG/EndoGI complex: Mechanism of EndoG inhibition | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CG4930, CG8862, ... | | 著者 | Loll, B, Gebhardt, M, Wahle, E, Meinhart, A. | | 登録日 | 2009-08-26 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
Nucleic Acids Res., 37, 2009
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1I9K
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2YGV
 | | Conserved N-terminal domain of the yeast Histone Chaperone Asf1 in complex with the C-terminal fragment of Rad53 | | 分子名称: | GLYCEROL, HISTONE CHAPERONE ASF1, SERINE/THREONINE-PROTEIN KINASE RAD53, ... | | 著者 | Jiao, Y, Seeger, K, Murciano, B, Ledu, M.H, Charbonnier, J.B, Legrand, P, Lautrette, A, Gaubert, A, Mousson, F, Guerois, R, Mann, C, Ochsenbein, F. | | 登録日 | 2011-04-21 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Surprising Complexity of the Asf1 Histone Chaperone-Rad53 Kinase Interaction
Proc.Natl.Acad.Sci.USA, 109, 2012
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2CK3
 | | Azide inhibited bovine F1-ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ... | | 著者 | Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. | | 登録日 | 2006-04-10 | | 公開日 | 2006-05-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | How Azide Inhibits ATP Hydrolysis by the F-Atpases.
Proc.Natl.Acad.Sci.USA, 103, 2006
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4BLW
 | | Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ in complex with S-adenosylhomocysteine (AdoHcy) and Adenosine monophosphate (AMP) | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, GLYCEROL, ... | | 著者 | Punekar, A.S, Liljeruhm, J, Shepherd, T.R, Forster, A.C, Selmer, M. | | 登録日 | 2013-05-04 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and Functional Insights Into the Molecular Mechanism of Rrna M6A Methyltransferase Rlmj.
Nucleic Acids Res., 41, 2013
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3J4B
 | | Structure of T7 gatekeeper protein (gp11) | | 分子名称: | Tail tubular protein A | | 著者 | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | | 登録日 | 2013-07-09 | | 公開日 | 2013-08-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Structural characterization of the bacteriophage t7 tail machinery.
J.Biol.Chem., 288, 2013
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2YTY
 | | Solution structure of the fourth cold-shock domain of the human KIAA0885 protein (UNR protein) | | 分子名称: | Cold shock domain-containing protein E1 | | 著者 | Goroncy, A.K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-05 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein.
J.Struct.Funct.Genom., 11, 2010
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2OT7
 | | Crystal structure of JMJD2A complexed with histone H3 peptide monomethylated at Lys9 | | 分子名称: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-07 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.135 Å) | | 主引用文献 | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
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2OO3
 | | Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519 | | 分子名称: | Protein involved in catabolism of external DNA, SULFATE ION | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Slocombe, A, Reyes, C, Ozyurt, S, Smyth, L, Atwell, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-01-25 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the hypothetical lpl1258 protein from Legionella pneumophila
To be Published
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6K9C
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2AIB
 | | beta-cinnamomin in complex with ergosterol | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-elicitin cinnamomin, ERGOSTEROL, ... | | 著者 | Rodrigues, M.L, Archer, M, Martel, P, Miranda, S, Thomaz, M, Enguita, F.J, Baptista, R.P, Melo, E.P, Sousa, N, Cravador, A, Carrondo, M.A. | | 登録日 | 2005-07-29 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal structures of the free and sterol-bound forms of beta-cinnamomin
Biochim.Biophys.Acta, 1764, 2006
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2NLR
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2HHM
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2HOG
 | | crystal structure of Chek1 in complex with inhibitor 20 | | 分子名称: | (5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL, Serine/threonine-protein kinase Chk1 | | 著者 | Yan, Y, Ikuta, M. | | 登録日 | 2006-07-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.
Bioorg.Med.Chem.Lett., 16, 2006
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2AYP
 | | Crystal Structure of CHK1 with an Indol Inhibitor | | 分子名称: | (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE, Serine/threonine-protein kinase Chk1 | | 著者 | Lin, N.-H, Xia, P, Kovar, P, Chen, Z, Zhang, H, Rosenberg, S.H, Sham, H.L. | | 登録日 | 2005-09-07 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
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2AYQ
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6K9E
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1L1L
 | | CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | | 分子名称: | RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE | | 著者 | Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L. | | 登録日 | 2002-02-18 | | 公開日 | 2002-04-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
Nat.Struct.Biol., 9, 2002
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2DTJ
 | | Crystal structure of regulatory subunit of aspartate kinase from Corynebacterium glutamicum | | 分子名称: | Aspartokinase, CITRIC ACID, THREONINE | | 著者 | Yoshida, A, Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2006-07-12 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural Insight into Concerted Inhibition of alpha(2)beta(2)-Type Aspartate Kinase from Corynebacterium glutamicum
J.Mol.Biol., 368, 2007
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