6YA7
 
 | | Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, DNA replication licensing factor MCM2, ... | | 著者 | Dick, S.D, Cherepanov, P. | | 登録日 | 2020-03-11 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
|
|
5VW1
 | |
6YPC
 | | Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms | | 分子名称: | Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ... | | 著者 | Bellini, D, Zhang, Z, Barford, D. | | 登録日 | 2020-04-15 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex.
Nucleic Acids Res., 48, 2020
|
|
8ADD
 | | Viral tegument-like DUBs | | 分子名称: | ATP-dependent DNA helicase | | 著者 | Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U. | | 登録日 | 2022-07-08 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins.
Nat Commun, 13, 2022
|
|
8QU5
 | | mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2 | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | | 登録日 | 2023-10-13 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
|
|
6XLW
 | | Crystal structure of U2AF65 bound to AdML splice site sequence | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ... | | 著者 | Maji, D, Jenkins, J.L, Kielkopf, C.L. | | 登録日 | 2020-06-29 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
|
|
5YDD
 | | Crystal structure of C-terminal domain of Rv1828 from Mycobacterium tuberculosis | | 分子名称: | (6R,8S,9S)-8-(hydroxymethyl)-6,11,11-tris(oxidanyl)-9-propyl-dodecanoic acid, GLYCEROL, SODIUM ION, ... | | 著者 | Singh, S, Karthiekeyan, S. | | 登録日 | 2017-09-12 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Characteristics of the essential pathogenicity factor Rv1828, a MerR family transcription regulator from Mycobacterium tuberculosis.
FEBS J., 285, 2018
|
|
2AEO
 | | Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase | | 分子名称: | COPPER (II) ION, Cisplatin, Superoxide dismutase [Cu-Zn], ... | | 著者 | Calderone, V, Casini, A, Mangani, S, Messori, L, Orioli, P.L. | | 登録日 | 2005-07-23 | | 公開日 | 2006-05-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.
Angew. Chem. Int. Ed. Engl., 45, 2006
|
|
6QYQ
 | | Crystal structure of human thymidylate synthase (hTS) variant R175C | | 分子名称: | CHLORIDE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... | | 著者 | Pozzi, C, Mangani, M. | | 登録日 | 2019-03-09 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors.
Molecules, 24, 2019
|
|
8I13
 | | Cryo-EM structure of 6-subunit Smc5/6 | | 分子名称: | MMS21 isoform 1, NSE3 isoform 1, Non-structural maintenance of chromosomes element 1 homolog, ... | | 著者 | Qian, L, Jun, Z, Xiang, Z, Cheng, T, Zhaoning, W, Duo, J, Zhenguo, C, Wang, L. | | 登録日 | 2023-01-12 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 31, 2024
|
|
5WQD
 | |
5YDC
 | |
6YR7
 | | 14-3-3 sigma in complex with hDMX-342+367 peptide | | 分子名称: | 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Protein Mdm4 | | 著者 | Wolter, M, Srdanovic, S, Warriner, S, Wilson, A, Ottmann, C. | | 登録日 | 2020-04-19 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | | 主引用文献 | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study.
Febs J., 2022
|
|
6YR5
 | | 14-3-3 sigma in complex with hDMX-367 peptide | | 分子名称: | 14-3-3 protein sigma, Protein Mdm4, SULFATE ION | | 著者 | Wolter, M, Srdanovic, S, Ottman, C, Warriner, S, Wilson, A. | | 登録日 | 2020-04-19 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study.
Febs J., 2022
|
|
6YR6
 | | 14-3-3 sigma in complex with hDM2-186 peptide | | 分子名称: | 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, ... | | 著者 | Wolter, M, Srdanovic, S, Warriner, S, Wilson, A, Ottmann, C. | | 登録日 | 2020-04-19 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Understanding the interaction of 14-3-3 proteins with hDMX and hDM2: a structural and biophysical study.
Febs J., 2022
|
|
1T29
 | | Crystal structure of the BRCA1 BRCT repeats bound to a phosphorylated BACH1 peptide | | 分子名称: | BACH1 phosphorylated peptide, Breast cancer type 1 susceptibility protein | | 著者 | Shiozaki, E.N, Gu, L, Yan, N, Shi, Y. | | 登録日 | 2004-04-20 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
Mol.Cell, 14, 2004
|
|
1U64
 | | The Solution Structure of d(G3T4G4)2 | | 分子名称: | 5'-D(*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3' | | 著者 | Sket, P, Crnugelj, M, Plavec, J. | | 登録日 | 2004-07-29 | | 公開日 | 2004-10-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | d(G3T4G4) forms unusual dimeric G-quadruplex structure with the same general fold in the presence of K+, Na+ or NH4+ ions.
Bioorg.Med.Chem., 12, 2004
|
|
2A4J
 | | Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein | | 分子名称: | 17-mer peptide P1-XPC from DNA-repair protein complementing XP-C cells, Centrin 2 | | 著者 | Yang, A, Miron, S, Mouawad, L, Duchambon, P, Blouquit, Y, Craescu, C.T. | | 登録日 | 2005-06-29 | | 公開日 | 2005-07-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein (XPC) from nuclear excision repair.
Biochemistry, 45, 2006
|
|
1ITG
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES | | 分子名称: | CACODYLATE ION, HIV-1 INTEGRASE | | 著者 | Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R. | | 登録日 | 1994-11-21 | | 公開日 | 1995-05-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
|
|
2M3A
 | |
1IME
 | |
5HS3
 | | Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol, Thymidylate synthase | | 著者 | Chen, D, Almqvist, H, Axelsson, H, Jafari, R, Mateus, A, Haraldsson, M, Larsson, A, Artursson, P, Molina, D.M, Lundback, T, Nordlund, P. | | 登録日 | 2016-01-25 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | | 主引用文献 | CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Nat Commun, 7, 2016
|
|
3VHS
 | |
2DCH
 | | Crystal structure of archaeal intron-encoded homing endonuclease I-Tsp061I | | 分子名称: | CHLORIDE ION, SULFATE ION, putative homing endonuclease | | 著者 | Nakayama, H, Tsuge, H, Shimamura, T, Miyano, M, Nomura, N, Sako, Y. | | 登録日 | 2006-01-06 | | 公開日 | 2006-07-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp061I: contribution of cross-domain polar networks to thermostability.
J.Mol.Biol., 365, 2007
|
|
4DDI
 | |
