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1CI6
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TRANSCRIPTION FACTOR ATF4-C/EBP BETA BZIP HETERODIMER
分子名称: BETA-MERCAPTOETHANOL, FE (III) ION, TRANSCRIPTION FACTOR ATF-4, ...
著者Podust, L.M, Kim, Y.
登録日1999-04-07
公開日2000-12-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the CCAAT box/enhancer-binding protein beta activating transcription factor-4 basic leucine zipper heterodimer in the absence of DNA
J.Biol.Chem., 276, 2001
5UWU
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Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
1CWH
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HUMAN CYCLOPHILIN A COMPLEXED WITH 3-D-SER CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-07
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
5ULA
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Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402
分子名称: 3-chloranyl-~{N}-(4-methoxyphenyl)-4-[(2-methyl-3-oxidanylidene-cyclopenten-1-yl)amino]benzamide, Bromodomain-containing protein 4
著者Plotnikov, A.N, Joshua, j, Zhou, M.-M.
登録日2017-01-24
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UNA
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Fragment of 7SK snRNA methylphosphate capping enzyme
分子名称: 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, unidentified peptide section/fragment
著者Wu, H, Tempel, W, Dombrovski, L, McCarthy, A.A, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC)
登録日2017-01-30
公開日2017-03-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Fragment of 7SK snRNA methylphosphate capping enzyme
To Be Published
8EQ8
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The crystal structure of 14-3-3 Beta containing 3-nitrotyrosine at position Y130
分子名称: 14-3-3 protein beta/alpha
著者Zhu, P, Cooley, R.B.
登録日2022-10-07
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation.
Protein Sci., 32, 2023
5UWR
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Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
8EQH
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The crystal structure of 14-3-3 Beta containing 3-nitrotyrosine at position Y213
分子名称: 14-3-3 protein beta/alpha
著者Zhu, P, Cooley, R.B.
登録日2022-10-07
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation.
Protein Sci., 32, 2023
8F0W
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Tudor Domain of Tumor suppressor p53BP1 with MFP-5956
分子名称: 1-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]butan-1-one, TP53-binding protein 1, UNKNOWN ATOM OR ION
著者The, J, Hong, Z, Dong, A, Headey, S, Gunzburg, M, Doak, B, James, L.I, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2022-11-04
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Tudor Domain of Tumor suppressor p53BP1 with MFP-5956
to be published
5V3O
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Cereblon in complex with DDB1 and CC-220
分子名称: (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ...
著者Matyskiela, M, Pagarigan, B, Chamberlain, P.
登録日2017-03-07
公開日2017-05-03
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos.
J. Med. Chem., 61, 2018
1A4P
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P11 (S100A10), LIGAND OF ANNEXIN II
分子名称: S100A10
著者Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A.
登録日1998-01-30
公開日1998-05-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Nat.Struct.Biol., 6, 1999
1AK4
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HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
分子名称: CYCLOPHILIN A, HIV-1 CAPSID
著者Hill, C.P, Gamble, T.R, Vajdos, F.F, Worthylake, D.K, Sundquist, W.I.
登録日1997-05-28
公開日1997-10-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
5UPD
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BU of 5upd by Molmil
Methyltransferase domain of human Wolf-Hirschhorn Syndrome Candidate 1-Like protein 1 (WHSC1L1)
分子名称: Histone-lysine N-methyltransferase NSD3, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, ...
著者Tempel, W, Yu, W, Dong, A, Cerovina, T, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
登録日2017-02-02
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Methyltransferase domain of human Wolf-Hirschhorn Syndrome Candidate 1-Like protein 1 (WHSC1L1)
To Be Published
1XNA
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BU of 1xna by Molmil
NMR SOLUTION STRUCTURE OF THE SINGLE-STRAND BREAK REPAIR PROTEIN XRCC1-N-TERMINAL DOMAIN
分子名称: PROTEIN (DNA-REPAIR PROTEIN XRCC1)
著者Marintchev, A, Mullen, G.P.
登録日1999-02-27
公開日1999-09-01
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the single-strand break repair protein XRCC1 N-terminal domain.
Nat.Struct.Biol., 6, 1999
1XNT
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BU of 1xnt by Molmil
NMR SOLUTION STRUCTURE OF THE SINGLE-STRAND BREAK REPAIR PROTEIN XRCC1-N-TERMINAL DOMAIN
分子名称: PROTEIN (DNA-REPAIR PROTEIN XRCC1)
著者Marintchev, A, Mullen, G.P.
登録日1999-02-27
公開日1999-09-01
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the single-strand break repair protein XRCC1 N-terminal domain.
Nat.Struct.Biol., 6, 1999
5T0J
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Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T1G
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chromo shadow domain of CBX1 in complex with a histone peptide
分子名称: Chromobox protein homolog 1, Histone H3.1, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-08-19
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献chromo shadow domain of CBX1 in complex with a histone peptide
To Be Published
5T1I
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CBX3 chromo shadow domain in complex with histone H3 peptide
分子名称: Chromobox protein homolog 3, Histone H3.1, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-08-19
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.
J. Biol. Chem., 292, 2017
1CWI
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN
分子名称: CYCLOSPORIN D, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-25
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1XNI
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Tandem Tudor Domain of 53BP1
分子名称: Tumor suppressor p53-binding protein 1
著者Huyen, Y, Zgheib, O, DiTullio Jr, R.A, Gorgoulis, V.G, Zacharatos, P, Petty, T.J, Sheston, E.A, Mellert, H.S, Stavridi, E.S, Halazonetis, T.D.
登録日2004-10-05
公開日2004-11-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
Nature, 432, 2004
1CWM
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-26
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1CMI
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STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE
分子名称: Dynein light chain 1, cytoplasmic, Nitric oxide synthase 1
著者Liang, J, Guo, W, Jaffery, S, Snyder, S, Clardy, J.
登録日1999-05-06
公開日2000-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the PIN/LC8 dimer with a bound peptide.
Nat.Struct.Biol., 6, 1999
1D4A
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CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AT 1.7 A RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, QUINONE REDUCTASE
著者Faig, M, Bianchet, M.A, Chen, S, Winski, S, Ross, D, Amzel, L.M.
登録日1999-10-01
公開日1999-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release.
Proc.Natl.Acad.Sci.USA, 97, 2000
1CWL
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HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D.
登録日1998-05-26
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
1A8A
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RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOSERINE
分子名称: ANNEXIN V, CALCIUM ION, L-ALPHA-GLYCEROPHOSPHORYLSERINE
著者Swairjo, M.A, Concha, N.O, Kaetzel, M.A, Dedman, J.R, Seaton, B.A.
登録日1998-03-23
公開日1998-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ca(2+)-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V.
Nat.Struct.Biol., 2, 1995

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