7TMQ
 
 | | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ... | | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | 登録日 | 2022-01-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TMP
 | | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ... | | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | 登録日 | 2022-01-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TMM
 | | Complete V1 Complex from Saccharomyces cerevisiae | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-ATPase subunit E, ... | | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | 登録日 | 2022-01-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TMO
 | | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, H(+)-transporting two-sector ATPase, ... | | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | 登録日 | 2022-01-19 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TMR
 | | V-ATPase from Saccharomyces cerevisiae, State 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ... | | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | | 登録日 | 2022-01-19 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
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7TYR
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2RP3
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2U2A
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2WTI
 | | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | | 分子名称: | 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ... | | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | | 登録日 | 2009-09-16 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
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2VJF
 | | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | | 登録日 | 2007-12-10 | | 公開日 | 2008-05-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
Cell Death Differ., 15, 2008
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2WTJ
 | | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ... | | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | | 登録日 | 2009-09-16 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
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2VJE
 | | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | | 登録日 | 2007-12-10 | | 公開日 | 2008-05-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Cell Death Differ., 15, 2008
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2XVS
 | | Crystal structure of human TTC5 (Strap) C-terminal OB domain | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, IODIDE ION, ... | | 著者 | Adams, J, Pike, A.C.W, Maniam, S, Sharpe, T.D, Coutts, A.S, Knapp, S, La Thangue, B, Bullock, A.N. | | 登録日 | 2010-10-31 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3UMZ
 | | Crystal Structure of the human MDC1 FHA Domain | | 分子名称: | Mediator of DNA damage checkpoint protein 1 | | 著者 | Luo, S, Ye, K. | | 登録日 | 2011-11-15 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
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3UNM
 | | Crystal Structure of The Human MDC1 FHA Domain | | 分子名称: | Mediator of DNA damage checkpoint protein 1 | | 著者 | Luo, S, Ye, K. | | 登録日 | 2011-11-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
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3VA4
 | | Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide | | 分子名称: | Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2 | | 著者 | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | | 登録日 | 2011-12-28 | | 公開日 | 2012-02-01 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
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4AXP
 | | NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | | 分子名称: | 12 KDA HEAT SHOCK PROTEIN | | 著者 | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | | 登録日 | 2012-06-13 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast.
Plos One, 7, 2012
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7DH3
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7FDA
 | | CryoEM Structure of Reconstituted V-ATPase, state1 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDC
 | | CryoEM Structures of Reconstituted V-ATPase, state3 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDB
 | | CryoEM Structures of Reconstituted V-ATPase,State2 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDE
 | | CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1 | | 分子名称: | Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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6KE6
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6KJ1
 | | 200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A | | 分子名称: | RNA-binding protein FUS | | 著者 | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | | 登録日 | 2019-07-20 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.65 Å) | | 主引用文献 | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
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6V2F
 | | Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting inhibitor, GS-6207 | | 分子名称: | HIV-1 capsid, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide | | 著者 | Appleby, T.C, Link, J.O, Yant, S.R, Villasenor, A.G, Somoza, J.R, Hu, E.Y, Schroeder, S.D, Cihlar, T. | | 登録日 | 2019-11-22 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature, 584, 2020
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