7TMQ
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![BU of 7tmq by Molmil](/molmil-images/mine/7tmq) | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ... | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | 登録日 | 2022-01-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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7TMP
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![BU of 7tmp by Molmil](/molmil-images/mine/7tmp) | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ... | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | 登録日 | 2022-01-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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7TMM
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![BU of 7tmm by Molmil](/molmil-images/mine/7tmm) | Complete V1 Complex from Saccharomyces cerevisiae | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-ATPase subunit E, ... | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | 登録日 | 2022-01-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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7TMO
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![BU of 7tmo by Molmil](/molmil-images/mine/7tmo) | V1 complex lacking subunit C from Saccharomyces cerevisiae, State 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, H(+)-transporting two-sector ATPase, ... | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | 登録日 | 2022-01-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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7TMR
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![BU of 7tmr by Molmil](/molmil-images/mine/7tmr) | V-ATPase from Saccharomyces cerevisiae, State 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ... | 著者 | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | 登録日 | 2022-01-19 | 公開日 | 2022-04-13 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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7TYR
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![BU of 7tyr by Molmil](/molmil-images/mine/7tyr) | |
2RP3
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![BU of 2rp3 by Molmil](/molmil-images/mine/2rp3) | |
2U2A
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![BU of 2u2a by Molmil](/molmil-images/mine/2u2a) | |
2WTI
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![BU of 2wti by Molmil](/molmil-images/mine/2wti) | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | 分子名称: | 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ... | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | 登録日 | 2009-09-16 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
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2VJF
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![BU of 2vjf by Molmil](/molmil-images/mine/2vjf) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | 登録日 | 2007-12-10 | 公開日 | 2008-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans. Cell Death Differ., 15, 2008
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2WTJ
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![BU of 2wtj by Molmil](/molmil-images/mine/2wtj) | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ... | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | 登録日 | 2009-09-16 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
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2VJE
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![BU of 2vje by Molmil](/molmil-images/mine/2vje) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | 登録日 | 2007-12-10 | 公開日 | 2008-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ., 15, 2008
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2XVS
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![BU of 2xvs by Molmil](/molmil-images/mine/2xvs) | Crystal structure of human TTC5 (Strap) C-terminal OB domain | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, IODIDE ION, ... | 著者 | Adams, J, Pike, A.C.W, Maniam, S, Sharpe, T.D, Coutts, A.S, Knapp, S, La Thangue, B, Bullock, A.N. | 登録日 | 2010-10-31 | 公開日 | 2010-11-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure. Proc.Natl.Acad.Sci.USA, 109, 2012
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3UMZ
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![BU of 3umz by Molmil](/molmil-images/mine/3umz) | Crystal Structure of the human MDC1 FHA Domain | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Luo, S, Ye, K. | 登録日 | 2011-11-15 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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3UNM
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![BU of 3unm by Molmil](/molmil-images/mine/3unm) | Crystal Structure of The Human MDC1 FHA Domain | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Luo, S, Ye, K. | 登録日 | 2011-11-16 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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3VA4
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![BU of 3va4 by Molmil](/molmil-images/mine/3va4) | Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide | 分子名称: | Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2 | 著者 | Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D. | 登録日 | 2011-12-28 | 公開日 | 2012-02-01 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68. Biochemistry, 2012
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4AXP
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![BU of 4axp by Molmil](/molmil-images/mine/4axp) | NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | 分子名称: | 12 KDA HEAT SHOCK PROTEIN | 著者 | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | 登録日 | 2012-06-13 | 公開日 | 2012-08-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast. Plos One, 7, 2012
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7DH3
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![BU of 7dh3 by Molmil](/molmil-images/mine/7dh3) | |
7FDA
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![BU of 7fda by Molmil](/molmil-images/mine/7fda) | CryoEM Structure of Reconstituted V-ATPase, state1 | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | 登録日 | 2021-07-16 | 公開日 | 2021-12-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDC
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![BU of 7fdc by Molmil](/molmil-images/mine/7fdc) | CryoEM Structures of Reconstituted V-ATPase, state3 | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | 登録日 | 2021-07-16 | 公開日 | 2021-12-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDB
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![BU of 7fdb by Molmil](/molmil-images/mine/7fdb) | CryoEM Structures of Reconstituted V-ATPase,State2 | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | 登録日 | 2021-07-16 | 公開日 | 2021-12-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDE
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![BU of 7fde by Molmil](/molmil-images/mine/7fde) | CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1 | 分子名称: | Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | 登録日 | 2021-07-16 | 公開日 | 2021-12-29 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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6KE6
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![BU of 6ke6 by Molmil](/molmil-images/mine/6ke6) | |
6KJ1
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![BU of 6kj1 by Molmil](/molmil-images/mine/6kj1) | 200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A | 分子名称: | RNA-binding protein FUS | 著者 | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | 登録日 | 2019-07-20 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.65 Å) | 主引用文献 | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
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6V2F
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![BU of 6v2f by Molmil](/molmil-images/mine/6v2f) | Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting inhibitor, GS-6207 | 分子名称: | HIV-1 capsid, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide | 著者 | Appleby, T.C, Link, J.O, Yant, S.R, Villasenor, A.G, Somoza, J.R, Hu, E.Y, Schroeder, S.D, Cihlar, T. | 登録日 | 2019-11-22 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature, 584, 2020
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