PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7CGQ	Crystal structure of Azospirillum brasilense L-arabinose 1-dehydrogenase E147A mutant (NADP and L-arabinose bound form) 分子名称: L-arabinose 1-dehydrogenase (NAD(P)(+)), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, alpha-L-arabinopyranose 著者 Yoshiwara, K, Watanabe, Y, Watanabe, S. 登録日 2020-07-02 公開日 2020-07-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.208 Å) 主引用文献 Crystal structure of bacterial L-arabinose 1-dehydrogenase in complex with L-arabinose and NADP+ Biochem.Biophys.Res.Commun., 530, 2020
7CHJ	crystal structure of pco4 分子名称: CITRIC ACID, FE (III) ION, Plant cysteine oxidase 4 著者 Guo, Q, Xu, C, Liao, S. 登録日 2020-07-05 公開日 2020-11-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. J.Struct.Biol., 213, 2021
7C3N	Crystal structure of JAK3 in complex with Delgocitinib 分子名称: 3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile, Tyrosine-protein kinase JAK3 著者 Doi, S, Otira, T, Kikuwaka, M, Nomura, A, Noji, S, Adachi, T. 登録日 2020-05-13 公開日 2020-06-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders. J.Med.Chem., 63, 2020
7C4N	Ancestral L-amino acid oxidase (AncLAAO-N5) L-Phe binding form 分子名称: Ancestral L-amino acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, PHENYLALANINE 著者 Nakano, S, Minamino, Y, Karasuda, H, Ito, S. 登録日 2020-05-18 公開日 2020-12-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids Commun Chem, 3, 2020
7CL5	The crystal structure of KanJ in complex with kanamycin B and N-oxalylglycine 分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Kanamycin B dioxygenase, N-OXALYLGLYCINE, ... 著者 Kitayama, Y, Miyanaga, A, Kudo, F, Eguchi, T. 登録日 2020-07-20 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis. Chembiochem, 22, 2021
7CN2	Subparticle refinement of human papillomavirus type 16 pesudovirus in complex with H16.001 Fab 分子名称: Major capsid protein L1, The heavy chain variable region of H16.001 Fab fragment, The light chain variable region of H16.001 Fab fragment 著者 He, M.Z, Li, S.W. 登録日 2020-07-29 公開日 2020-09-02 最終更新日 2021-03-17 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs. Npj Vaccines, 5, 2020
7CA5	Cryo-EM structure of human GABA(B) receptor in apo state 分子名称: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2 著者 Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. 登録日 2020-06-08 公開日 2020-11-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432, 2020
7CBO	Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila in complex with GlcNAc 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, GLYCEROL, ... 著者 Xu, W, Wang, M, Zhang, M. 登録日 2020-06-13 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural and biochemical analyses of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila involved in mucin degradation. Biochem.Biophys.Res.Commun., 529, 2020
7CR7	human KCNQ2-CaM in complex with retigabine 分子名称: Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate 著者 Li, X, Lv, D, Wang, J, Ye, S, Guo, J. 登録日 2020-08-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
7CCW	Crystal structure of death-associated protein kinase 1 in complex with resveratrol and MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Death-associated protein kinase 1, RESVERATROL, ... 著者 Yokoyama, T, Suzuki, R, Mizuguchi, M. 登録日 2020-06-18 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of death-associated protein kinase 1 in complex with the dietary compound resveratrol. Iucrj, 8, 2020
7C3H	Structure of L-lysine oxidase in complex with L-lysine 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Kondo, H, Kitagawa, M, Sugiyama, S, Imada, K. 登録日 2020-05-12 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride. Protein Sci., 29, 2020
7C4L	Anncestral L-amino acid oxidase (AncLAAO-N5) L-Gln binding form 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTAMINE, L-amino acid oxidase 著者 Nakano, S, Minamino, Y, Karasuda, H, Ito, S. 登録日 2020-05-18 公開日 2020-12-02 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids Commun Chem, 3, 2020
7C6U	Crystal structure of SARS-CoV-2 complexed with GC376 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase 著者 Fu, L, Feng, Y, Qi, J, Gao, F.G. 登録日 2020-05-22 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020
7CR0	human KCNQ2 in apo state 分子名称: Potassium voltage-gated channel subfamily KQT member 2 著者 Li, X, Lv, D, Wang, J, Ye, S, Guo, J. 登録日 2020-08-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
7C83	Crystal structure of an integral membrane steroid 5-alpha-reductase PbSRD5A 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oxo-5-alpha-steroid 4-dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Ren, R.B, Han, Y.F, Xiao, Q.J, Deng, D. 登録日 2020-05-28 公開日 2021-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. Nat Commun, 12, 2021
7CBN	Crystal structure of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila 分子名称: Beta-N-acetylhexosaminidase, GLYCEROL, MALONIC ACID 著者 Xu, W, Wang, M, Zhang, M. 登録日 2020-06-13 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and biochemical analyses of beta-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila involved in mucin degradation. Biochem.Biophys.Res.Commun., 529, 2020
7CFT	Cryo-EM strucutre of human acid-sensing ion channel 1a in complex with snake toxin Mambalgin1 at pH 8.0 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Mambalgin-1 著者 Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L. 登録日 2020-06-28 公開日 2020-10-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9, 2020
7CM7	NAD+-bound Sarm1 E642A in the self-inhibited state 分子名称: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Zhang, Z, Jiang, Y. 登録日 2020-07-25 公開日 2020-10-21 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
7CPY	Lovastatin nonaketide synthase with LovC 分子名称: Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... 著者 Wang, J, Wang, Z. 登録日 2020-08-08 公開日 2021-01-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
7C2A	Crystal structure of AlinE4, a SGNH-hydrolase family esterase 分子名称: ACETATE ION, CADMIUM ION, SGNH-hydrolase family esterase 著者 Li, Z, Li, J. 登録日 2020-05-07 公開日 2020-05-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 C-terminal swapped dimers revealed a new catalytic mechanism of SGNH-hydrolase family esterases To Be Published
7CPP	THE STRUCTURAL BASIS FOR SUBSTRATE-INDUCED CHANGES IN REDOX POTENTIAL AND SPIN EQUILIBRIUM IN CYTOCHROME P450(CAM) 分子名称: CYTOCHROME P450-CAM, NORCAMPHOR, PROTOPORPHYRIN IX CONTAINING FE 著者 Raag, R, Poulos, T.L. 登録日 1990-05-18 公開日 1991-07-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM. Biochemistry, 28, 1989
7CR3	human KCNQ2-CaM in apo state 分子名称: Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2 著者 Li, X, Lv, D, Wang, J, Ye, S, Guo, J. 登録日 2020-08-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
7C94	Crystal structure of the anti-human podoplanin antibody Fab fragment complex with glycopeptide 分子名称: GLYCEROL, Heavy chain of Fab fragment, Light chain of Fab fragment, ... 著者 Suzuki, K, Nakamura, S, Ogasawara, S, Naruchi, K, Shimabukuro, J, Tukahara, N, Kaneko, M.K, Kato, Y, Murata, T. 登録日 2020-06-04 公開日 2020-09-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Crystal structure of an anti-podoplanin antibody bound to a disialylated O-linked glycopeptide. Biochem.Biophys.Res.Commun., 533, 2020
7CRP	NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) 分子名称: DNA (168-MER), Histone H2A, Histone H2B, ... 著者 Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. 登録日 2020-08-14 公開日 2020-10-21 最終更新日 2021-03-03 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590, 2021
7CGP	Cryo-EM structure of the human mitochondrial translocase TIM22 complex at 3.7 angstrom. 分子名称: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acylglycerol kinase, mitochondrial, ... 著者 Qi, L, Wang, Q, Guan, Z, Yan, C, Yin, P. 登録日 2020-07-01 公開日 2020-10-14 最終更新日 2021-03-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the human mitochondrial translocase TIM22 complex. Cell Res., 31, 2021

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