PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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5L1F	AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor Perampanel 分子名称: 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 著者 Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. 登録日 2016-07-29 公開日 2016-10-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91, 2016
6KBR	Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex 分子名称: GLYCEROL, K41043, Kallikrein-4 著者 Kawaguchi, Y, Nishimiya, D. 登録日 2019-06-26 公開日 2019-07-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases. Sci Rep, 9, 2019
6S2J	Square conformation of KtrA R16K mutant ring with bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, MAGNESIUM ION 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-06-21 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
8TT1	Pseudomonas fluorescens isocyanide hydratase pH=5.0 分子名称: Isonitrile hydratase InhA 著者 Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. 登録日 2023-08-12 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography. Biorxiv, 2023
6B9E	Human ATL1 mutant - R77A / F151S bound to GDP 分子名称: Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 O'Donnell, J.P, Sondermann, H. 登録日 2017-10-10 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
1GUN	MopII from Clostridium pasteurianum complexed with molybdate (partial) 分子名称: CALCIUM ION, MOLYBDATE BINDING PROTEIN II, MOLYBDATE ION 著者 Schuettelkopf, A.W, Harrison, J.A, Hunter, W.N. 登録日 2002-01-28 公開日 2002-02-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Passive Acquisition of Ligand by the Mopii Molbindin from Clostridium Pasteurianum: Structures of Apo and Oxyanion-Bound Forms J.Biol.Chem., 277, 2002
8B9W	Cysteine Synthase from Trypanosoma theileri with PLP bound 分子名称: CHLORIDE ION, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Sowerby, K.V, Pohl, E. 登録日 2022-10-10 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
8B9M	Cysteine Synthase from Leishmania Infantum 分子名称: CHLORIDE ION, Cysteine synthase, GLYCEROL 著者 Sowerby, K.V, Pohl, E. 登録日 2022-10-06 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
5N6X	Crystal structure of the Legionella effector WipA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BETA-MERCAPTOETHANOL, BROMIDE ION, ... 著者 Pinotsis, N, Waksman, G. 登録日 2017-02-16 公開日 2017-04-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila. J. Biol. Chem., 292, 2017
8BLQ	Cryo-EM structure of the CODV-IL13-RefAb triple complex 分子名称: CODV-Fab, heavy chain, light chain, ... 著者 Fernandez-Martinez, D, Kandiah, E. 登録日 2022-11-10 公開日 2023-06-07 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM. Sci Rep, 13, 2023
5L0D	Human Metavinculin(residues 959-1130) in complex with PIP2 分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
2OFQ	NMR Solution Structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system 分子名称: TraN, TraO 著者 Harris, R, Bayliss, R, Driscoll, P.C, Waksman, G. 登録日 2007-01-04 公開日 2007-01-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system Proc.Natl.Acad.Sci.Usa, 104, 2007
6OAX	Structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Hyperactive disaggregase ClpB, ... 著者 Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. 登録日 2019-03-18 公開日 2019-06-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
1CR5	N-TERMINAL DOMAIN OF SEC18P 分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, SEC18P (RESIDUES 22 - 210) 著者 Babor, S.M, Fass, D. 登録日 1999-08-13 公開日 1999-12-22 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Sec18p N-terminal domain. Proc.Natl.Acad.Sci.USA, 96, 1999
2GJ3	Crystal structure of the FAD-containing PAS domain of the protein NifL from Azotobacter vinelandii. 分子名称: ETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, Nitrogen fixation regulatory protein, ... 著者 Key, J, Hefti, M, Purcell, E, Moffat, K. 登録日 2006-03-30 公開日 2007-03-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution: signaling, dimerization, and mechanism. Biochemistry, 46, 2007
6RKT	Crystal Structure of TGT in complex with N2-methyl-1H,7H,8H-imidazo[4,5-g]quinazoline-2,6-diamine 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Hassaan, E, Heine, A, Klebe, G. 登録日 2019-04-30 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT. J.Med.Chem., 63, 2020
8IQY	Asterias forbesii ferritin mutant-P156H 分子名称: Ferritin 著者 Zhao, G, Zhang, C, Zang, J, Zhang, T. 登録日 2023-03-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Preparation and Unique Three-Dimensional Self-Assembly Property of Starfish Ferritin. Foods, 12, 2023
8IQW	AfFer(Asterias forbesii ferritin) mutant-P156H 分子名称: Ferritin 著者 Zhao, G, Zhang, C, Zang, J, Zhang, T. 登録日 2023-03-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Preparation and Unique Three-Dimensional Self-Assembly Property of Starfish Ferritin. Foods, 12, 2023
8R3L	Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8IQV	Asterias forbesii ferritin 分子名称: Ferritin 著者 Zhao, G, Zhang, C, Zang, J, Zhang, T. 登録日 2023-03-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Preparation and Unique Three-Dimensional Self-Assembly Property of Starfish Ferritin. Foods, 12, 2023
8IQZ	Asterias forbesii ferritin mutant-P156F 分子名称: Ferritin 著者 Zhao, G, Zhang, C, Zang, J, Zhang, T. 登録日 2023-03-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.19 Å) 主引用文献 Preparation and Unique Three-Dimensional Self-Assembly Property of Starfish Ferritin. Foods, 12, 2023
6RUU	Pseudokinase domain of human IRAK3 分子名称: GLYCEROL, Interleukin-1 receptor-associated kinase 3, MERCURY (II) ION, ... 著者 Lange, S.M, Kulathu, Y, Cohen, P. 登録日 2019-05-29 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation. Structure, 29, 2021
6OJT	Crystal structure of Sphingomonas paucimobilis TMY1009 LsdA phenylazophenol complex 分子名称: 4-Hydroxyazobenzene, FE (III) ION, Lignostilbene-alpha,beta-dioxygenase isozyme I 著者 Kuatsjah, E, Verstraete, M.M, Kobylarz, M.J, Liu, A.K.N, Murphy, M.E.P, Eltis, L.D. 登録日 2019-04-12 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. J.Biol.Chem., 294, 2019
6RX3	Crystal structure of human syncytin 2 in post-fusion conformation 分子名称: CHLORIDE ION, Syncytin-2 著者 Ruigrok, K, Backovic, M, Vaney, M.C, Rey, F.A. 登録日 2019-06-07 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications. J.Mol.Biol., 431, 2019
5IIR	NMR Structures Show Unwinding of the GCN4p Coiled Coil Superhelix Accompanying Disruption of Ion Pairs at Acidic pH 分子名称: General control protein GCN4 著者 Brady, M.R, Kaplan, A.R, Alexandrescu, A.T. 登録日 2016-03-01 公開日 2017-03-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix. Biochemistry, 56, 2017

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