6RUU

Pseudokinase domain of human IRAK3

Summary for 6RUU

Entry DOI	10.2210/pdb6ruu/pdb
Descriptor	Interleukin-1 receptor-associated kinase 3, MERCURY (II) ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	pseudokinase, homo-dimer, innate immunity, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	111178.09
Authors	Lange, S.M.,Kulathu, Y.,Cohen, P. (deposition date: 2019-05-29, release date: 2020-09-09, Last modification date: 2024-01-24)
Primary citation	Lange, S.M.,Nelen, M.I.,Cohen, P.,Kulathu, Y. Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation. Structure, 29:238-, 2021 Cited by PubMed: 33238146 DOI: 10.1016/j.str.2020.11.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation