PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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3PBU	Crystal structure of the mutant I96S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 分子名称: 6-AZA URIDINE 5'-MONOPHOSPHATE, Orotidine 5'-monophosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Iiams, V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-10-21 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.299 Å) 主引用文献 Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
3PC0	Crystal structure of the mutant V155S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 分子名称: 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, Orotidine 5'-monophosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Iiams, V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-10-21 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.298 Å) 主引用文献 Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
5LQS	Structure of quinolinate synthase Y21F mutant in complex with substrate-derived quinolinate 分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2016-08-17 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
5LQM	Structure of quinolinate synthase Y21F mutant in complex with citrate 分子名称: CITRATE ANION, IRON/SULFUR CLUSTER, Quinolinate synthase A 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2016-08-17 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
3MW7	Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP(produced from 5-fluoro-6-amino-UMP) 分子名称: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase 著者 Liu, Y, Kotra, L.P, Pai, E.F. 登録日 2010-05-05 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP(produced from 5-fluoro-6-amino-UMP) To be Published
3N3M	Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 6-amino-UMP 分子名称: 1,2-ETHANEDIOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, GLYCEROL, ... 著者 Liu, Y, Kotra, L.P, Pai, E.F. 登録日 2010-05-20 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 6-amino-UMP To be Published
2E25	The Crystal Structure of the T109S mutant of E. coli Dihydroorotase complexed with an inhibitor 5-fluoroorotate 分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION 著者 Lee, M, Maher, M.J, Guss, J.M. 登録日 2006-11-08 公開日 2007-03-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form Acta Crystallogr.,Sect.F, 63, 2007
7JMI	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 29 - State 3 (S3) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMJ	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 37 - State 5 (S5) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMG	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
2AIR	T-state Active Site of Aspartate Transcarbamylase:Crystal Structure of the Carbamyl Phosphate and L-alanosine Ligated Enzyme 分子名称: 3-[HYDROXY(NITROSO)AMINO]-L-ALANINE, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... 著者 Huang, J, Lipscomb, W.N. 登録日 2005-07-30 公開日 2006-01-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 T-State Active Site of Aspartate Transcarbamylase: Crystal Structure of the Carbamyl Phosphate and l-Alanosine Ligated Enzyme Biochemistry, 45, 2006
2AT1	CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH 分子名称: ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ... 著者 Gouaux, J.E, Lipscomb, W.N. 登録日 1989-09-22 公開日 1990-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH. Biochemistry, 29, 1990
3MJY	Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Aminoorotic acid 分子名称: 5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... 著者 Pinheiro, M.P, Rocha, J.R, Cheleski, J, Montanari, C.A, Nonato, M.C. 登録日 2010-04-13 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery. Eur.J.Med.Chem., 45, 2010
3MHU	Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Nitroorotic acid 分子名称: 5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... 著者 Pinheiro, M.P, Rocha, J.R, Cheleski, J, Montanari, C.A, Nonato, M.C. 登録日 2010-04-08 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery. Eur.J.Med.Chem., 45, 2010
2B0M	Human dihydroorotate dehydrogenase bound to a novel inhibitor 分子名称: 3-AMIDO-5-BIPHENYL-BENZOIC ACID, Dihydroorotate dehydrogenase, mitochondrial, ... 著者 Hurt, D.E, Sutton, A.E, Clardy, J. 登録日 2005-09-14 公開日 2005-09-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase. Bioorg.Med.Chem.Lett., 16, 2006
3NQC	Crystal structure of the mutant I96S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-06-29 公開日 2011-05-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.531 Å) 主引用文献 Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
3N2M	Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), ... 著者 Liu, Y, Kotra, L.P, Pai, E.F. 登録日 2010-05-18 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP To be Published
3N34	Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP 分子名称: 1,2-ETHANEDIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, ... 著者 Liu, Y, Kotra, L.P, Pai, E.F. 登録日 2010-05-19 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP To be Published
3MWA	Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase covalently modified by 2-prime-fluoro-6-iodo-UMP 分子名称: 2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, Orotidine 5'-phosphate decarboxylase, ... 著者 Liu, Y, Kotra, L.P, Pai, E.F. 登録日 2010-05-05 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase covalently modified by 2-prime-fluoro-6-iodo-UMP To be Published
2B4G	dihydroorotate dehydrogenase 分子名称: BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-09-23 公開日 2005-10-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies Mol.Microbiol., 68, 2008
2CZE	Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with UMP 分子名称: CITRIC ACID, GLYCEROL, Orotidine 5'-phosphate decarboxylase, ... 著者 Arai, R, Ito, K, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-13 公開日 2006-01-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with UMP To be Published
2CZD	Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 at 1.6 A resolution 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Orotidine 5'-phosphate decarboxylase 著者 Arai, R, Ito, K, Kamo-Uchikubo, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-13 公開日 2006-01-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 at 1.6 A resolution To be Published
2CZF	Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with XMP 分子名称: Orotidine 5'-phosphate decarboxylase, XANTHOSINE-5'-MONOPHOSPHATE 著者 Ito, K, Arai, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-13 公開日 2006-01-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with XMP To be Published
3PBV	Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate 分子名称: 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, Orotidine 5'-monophosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Iiams, V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-10-21 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50, 2011
2F84	Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from P.falciparum 分子名称: PHOSPHATE ION, orotidine monophosphate decarboxylase 著者 Caruthers, J.M, Robein, M, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-12-01 公開日 2005-12-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from Plasmodium falciparum To be Published

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