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2HF5
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The structure and function of a novel two-site calcium-binding fragment of calmodulin
分子名称: CALCIUM ION, Calmodulin
著者Lakowski, T.M, Lee, G.M, Reid, R.E, McIntosh, L.P.
登録日2006-06-23
公開日2007-05-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3
Protein Sci., 16, 2007
2H6D
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Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain)
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-2
著者Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-05-31
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
4F3A
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Structure of RPE65: P6522 crystal form, iridium derivative
分子名称: FE (II) ION, IRIDIUM (III) ION, Retinoid isomerohydrolase
著者Kiser, P.D, Palczewski, K.
登録日2012-05-09
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4QGA
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S.aureus TMK in complex with potent inhibitor compound 19, 2-(3-CHLOROPHENOXY)-3-FLUORO-4-{[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]METHYL}BENZOIC ACID
分子名称: 2-(3-chlorophenoxy)-3-fluoro-4-{[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]methyl}benzoic acid, Thymidylate kinase
著者Olivier, N.B.
登録日2014-05-22
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Antibacterial inhibitors of gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.
J.Med.Chem., 57, 2014
4QGH
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S.aureus TMK in complex with potent inhibitor compound 47
分子名称: 2-(3-chlorophenoxy)-3-fluoro-4-{(1S)-3-methyl-1-[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]butyl}benzoic acid, Thymidylate kinase
著者Olivier, N.B.
登録日2014-05-22
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Antibacterial inhibitors of gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.
J.Med.Chem., 57, 2014
2FV7
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Crystal structure of human ribokinase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribokinase, ...
著者Rabeh, W.M, Tempel, W, Nedyalkova, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-01-30
公開日2006-02-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human ribokinase
to be published
2FR5
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Crystal Structure of Mouse Cytidine Deaminase Complexed with Tetrahydrouridine
分子名称: Cytidine deaminase, SULFATE ION, TETRAHYDROURIDINE, ...
著者Teh, A.H.
登録日2006-01-19
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献The 1.48 A Resolution Crystal Structure of the Homotetrameric Cytidine Deaminase from Mouse
Biochemistry, 45, 2006
2K49
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Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis. Northeast Structural Genomics Consortium target SoR190
分子名称: UPF0339 protein SO_3888
著者Tang, Y, Wang, D, Nwosu, C, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-05-31
公開日2008-07-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of UPF0339 protein SO3888 from Shewanella oneidensis.
To be Published
4QGF
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S.aureus TMK in complex with the potent inhibitor compound 38, 2-(3-CHLOROPHENOXY)-3-METHOXY-4-{(1R)-1-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]PROPYL}BENZOIC ACID
分子名称: 2-(3-chlorophenoxy)-3-methoxy-4-{(1R)-1-[(3S)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl]propyl}benzoic acid, Thymidylate kinase
著者Olivier, N.B.
登録日2014-05-22
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Antibacterial inhibitors of gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.
J.Med.Chem., 57, 2014
6WB6
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2.05 A resolution structure of transferrin 1 from Manduca sexta
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Weber, J.J, Gorman, M.J.
登録日2020-03-26
公開日2020-11-25
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta.
Protein Sci., 30, 2021
2K1F
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SUMO-3 from Drosophila melanogaster (dsmt3)
分子名称: CG4494-PA
著者Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V.
登録日2008-03-03
公開日2009-03-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3).
Proteins, 75, 2009
7F4V
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BU of 7f4v by Molmil
Cryo-EM structure of a primordial cyanobacterial photosystem I
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Kato, K, Hamaguchi, T, Nagao, R, Kawakami, K, Yonekura, K, Shen, J.R.
登録日2021-06-21
公開日2022-04-06
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Structural basis for the absence of low-energy chlorophylls responsible for photoprotection from a primitive cyanobacterial PSI
Biorxiv, 2022
3SYZ
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BU of 3syz by Molmil
Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dNaM as templating nucleobase
分子名称: (5'-D(*AP*AP*AP*(BMN)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ...
著者Betz, K, Diederichs, K, Marx, A.
登録日2011-07-18
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.
Nat.Chem.Biol., 8, 2012
2K3X
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Solution structure of EAF3 chromo barrel domain
分子名称: Chromatin modification-related protein EAF3
著者Mer, G, Xu, C.
登録日2008-05-19
公開日2008-09-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S.
Structure, 16, 2008
6W9V
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Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H without ligand
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Awad, W, Rossjohn, J.
登録日2020-03-23
公開日2020-08-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 .
Sci Immunol, 5, 2020
4DXT
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Human SUN2 (AA 522-717)
分子名称: POTASSIUM ION, SUN domain-containing protein 2
著者Sosa, B, Schwartz, T.U.
登録日2012-02-28
公開日2012-06-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins.
Cell(Cambridge,Mass.), 149, 2012
2JXY
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BU of 2jxy by Molmil
Solution structure of the hemopexin-like domain of MMP12
分子名称: CALCIUM ION, Macrophage metalloelastase
著者Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M.
登録日2007-12-01
公開日2008-05-27
最終更新日2024-11-13
実験手法SOLUTION NMR
主引用文献Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12
J.Am.Chem.Soc., 130, 2008
4DYX
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Crystal Structure of the Cu-adduct of Human H-Ferritin variant 4His-delta C-star
分子名称: CALCIUM ION, COPPER (II) ION, Ferritin heavy chain
著者Tezcan, F.A, Huard, D.J.E.
登録日2012-02-29
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Re-engineering protein interfaces yields copper-inducible ferritin cage assembly.
Nat.Chem.Biol., 9, 2013
2K0J
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Solution structure of CaM complexed to DRP1p
分子名称: CALCIUM ION, LANTHANUM (III) ION, calmodulin
著者Bertini, I, Luchinat, C, Parigi, G, Yuan, J, Structural Proteomics in Europe (SPINE)
登録日2008-02-04
公開日2009-03-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples.
J.Am.Chem.Soc., 131, 2009
4TXL
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Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with uracil
分子名称: SULFATE ION, URACIL, Uridine phosphorylase
著者Marinho, A, Torini, J, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M.
登録日2014-07-03
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function.
Biochimie, 125, 2016
3X0R
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DP ribose pyrophosphatase from Thermus thermophilus HB8 in E'-state at reaction time of 30 min
分子名称: ADP-ribose pyrophosphatase, GLYCEROL, MANGANESE (II) ION, ...
著者Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N.
登録日2014-10-17
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors
Biochemistry, 55, 2016
2K01
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Structure of a locked SDF1 dimer
分子名称: Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-23
公開日2008-10-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
Sci.Signal., 1, 2008
2K05
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Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21
分子名称: C-X-C chemokine receptor type 4, Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-24
公開日2008-10-28
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12.
Sci.Signal., 1, 2008
2JA8
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CPD lesion containing RNA Polymerase II elongation complex D
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TP*TTP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*AP*UP)-3', ...
著者Brueckner, F, Hennecke, U, Carell, T, Cramer, P.
登録日2006-11-23
公開日2007-02-20
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Cpd Damage Recognition by Transcribing RNA Polymerase II.
Science, 315, 2007
4EQR
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Crystal structure of the Y361F mutant of Staphylococcus aureus CoADR
分子名称: CHLORIDE ION, COENZYME A, Coenzyme A disulfide reductase, ...
著者Wallace, B.D, Edwards, J.S, Wallen, J.R, Claiborne, A, Redinbo, M.R.
登録日2012-04-19
公開日2012-10-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights.
Biochemistry, 51, 2012

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