6W9V

Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H without ligand

Summary for 6W9V

• Entry DOI: 10.2210/pdb6w9v/pdb
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR-alpha chain, ... (7 entities in total)
• Functional Keywords: immune system, mait, mr1, metabolite
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 188548.48

Authors

Awad, W.,Rossjohn, J. (deposition date: 2020-03-23, release date: 2020-08-05, Last modification date: 2023-10-18)

• Primary citation: Howson, L.J.,Awad, W.,von Borstel, A.,Lim, H.J.,McWilliam, H.E.G.,Sandoval-Romero, M.L.,Majumdar, S.,Hamzeh, A.R.,Andrews, T.D.,McDermott, D.H.,Murphy, P.M.,Le Nours, J.,Mak, J.Y.W.,Liu, L.,Fairlie, D.P.,McCluskey, J.,Villadangos, J.A.,Cook, M.C.,Turner, S.J.,Davey, M.S.,Ojaimi, S.,Rossjohn, J.; Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 .; Sci Immunol, 5:-, 2020; PubMed: 32709702; DOI: 10.1126/sciimmunol.abc9492

Experimental method

X-RAY DIFFRACTION (1.95 Å)