PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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4ERP	Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit alpha, ... 著者 Zimanyi, C.M, Drennan, C.L. 登録日 2012-04-20 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.45 Å) 主引用文献 Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure, 20, 2012
5FSI	MTH1 substrate recognition: Complex with 8-oxo-dGTP. 分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2016-07-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
4ERM	Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex at 4 Angstroms resolution 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Zimanyi, C.M, Drennan, C.L. 登録日 2012-04-20 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure, 20, 2012
5FSK	MTH1 substrate recognition: Complex with 8-oxo-dGTP. 分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-ADENOSINE-5'-TRIPHOSPHATE, ACETATE ION 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2016-07-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
5FSM	MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide. 分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2016-07-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
4B2I	Humanised monomeric RadA in complex with indazole 分子名称: 1H-indazole, DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION 著者 Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. 登録日 2012-07-16 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Using a Fragment-Based Approach to Target Protein-Protein Interactions. Chembiochem, 14, 2013
4B3D	Humanised monomeric RadA in complex with 5-methyl indole 分子名称: 5-METHYL INDOLE, DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION 著者 Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. 登録日 2012-07-23 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.589 Å) 主引用文献 Using a Fragment-Based Approach to Target Protein-Protein Interactions. Chembiochem, 14, 2013
2M3A	NMR solution structure of a MYB-like DNA binding domain of KNL-2 from C. Elegans 分子名称: Protein KNL-2 著者 Osborne, M.J, Borden, L.B. 登録日 2013-01-15 公開日 2014-04-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Centromere epigenome stability is mediated by structural recognition by the Centromere Licensing Complex To be Published
8H68	Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Shi, Y, Ding, J, Yang, H. 登録日 2022-10-16 公開日 2023-02-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Caenorhabditis elegans NMAD-1 functions as a demethylase for actin. J Mol Cell Biol, 15, 2023
5FSN	MTH1 substrate recognition: Complex with a aminomethylpyrimidinyl oxypropanol. 分子名称: 3-(2-AMINO-6-METHYL-PYRIMIDIN-4-YL)OXYPROPAN-1-OL, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, ... 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2016-07-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
7XYF	Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome 分子名称: ATP-dependent helicase fft3, DNA (167-MER), Histone H2A, ... 著者 Nan, Z, Tao, J, Yangao, H. 登録日 2022-06-01 公開日 2023-12-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome (Class I Fft3-nucleosome complex) To Be Published
4B34	Humanised monomeric RadA in complex with 2-amino benzothiazole 分子名称: 1,3-benzothiazol-2-amine, DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION 著者 Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. 登録日 2012-07-20 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Using a Fragment-Based Approach to Target Protein-Protein Interactions. Chembiochem, 14, 2013
4B33	Humanised monomeric RadA in complex with napht-2-ol 分子名称: 1-NAPHTHOL, DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION 著者 Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. 登録日 2012-07-20 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Using a Fragment-Based Approach to Target Protein-Protein Interactions. Chembiochem, 14, 2013
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells 分子名称: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-11-17 公開日 2022-07-06 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
5FSL	MTH1 substrate recognition: Complex with a methylaminopurinone 分子名称: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 9-METHYL-2-(METHYLAMINO)-1H-PURIN-6-ONE, SULFATE ION 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2016-07-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
2O99	The crystal structure of E.coli IclR C-terminal fragment in complex with glyoxylate 分子名称: 1,2-ETHANEDIOL, Acetate operon repressor, GLYCOLIC ACID 著者 Lunin, V.V, Ezersky, A, Evdokimova, E, Kudritska, M, Savchenko, A. 登録日 2006-12-13 公開日 2007-04-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator. J.Biol.Chem., 282, 2007
5FSO	MTH1 substrate recognition: Complex with a methylaminopyrimidinedione. 分子名称: 6-(METHYLAMINO)-1H-PYRIMIDINE-2,4-DIONE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, ... 著者 Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. 登録日 2016-01-06 公開日 2017-01-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 MTH1 Substrate Recognition--An Example of Specific Promiscuity. PLoS ONE, 11, 2016
5HM5	Crystal structure of Topo-97, an N-terminal 97kDa fragment of topoisomerase V 分子名称: Topoisomerase V 著者 Rajan, R, Osterman, A, Mondragon, A. 登録日 2016-01-15 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Methanopyrus kandleri topoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site. Nucleic Acids Res., 44, 2016
5D17	Structure of the C-terminal domain of TnsE at 2.85 resolution 分子名称: Transposon Tn7 transposition protein TnsE 著者 Guarne, A, Caron, J.J. 登録日 2015-08-03 公開日 2015-09-30 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Conformational toggling controls target site choice for the heteromeric transposase element Tn7. Nucleic Acids Res., 43, 2015
6JVN	Crystal structure of human MTH1 in complex with compound MI1020 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N4-methyl-6-morpholin-4-yl-pyrimidine-2,4-diamine 著者 Peng, C, Li, Y.H, Cheng, Y.S. 登録日 2019-04-17 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
2O9A	The crystal structure of the E.coli IclR C-terminal fragment in complex with pyruvate. 分子名称: 1,2-ETHANEDIOL, Acetate operon repressor, PYRUVIC ACID 著者 Lunin, V.V, Ezersky, A, Evdokimova, E, Kudritska, M, Savchenko, A. 登録日 2006-12-13 公開日 2007-04-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator. J.Biol.Chem., 282, 2007
6JVS	Crystal structure of human MTH1 in complex with compound MI1029 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N4-cyclopropyl-6-[4-(oxetan-3-yl)piperazin-1-yl]pyrimidine-2,4-diamine 著者 Peng, C, Li, Y.H, Cheng, Y.S. 登録日 2019-04-17 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
6JVK	Crystal structure of human MTH1 in complex with compound MI1012 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N4-methyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine 著者 Peng, C, Li, Y.H, Cheng, Y.S. 登録日 2019-04-17 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
6JVT	Crystal structure of human MTH1 in complex with compound MI1030 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N4-methyl-6-[4-(oxetan-3-yl)piperazin-1-yl]pyrimidine-2,4-diamine 著者 Peng, C, Li, Y.H, Cheng, Y.S. 登録日 2019-04-17 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021
6JVJ	Crystal structure of human MTH1 in complex with compound MI1006 分子名称: 5-ethyl-N4-methyl-6-piperidin-1-yl-pyrimidine-2,4-diamine, 7,8-dihydro-8-oxoguanine triphosphatase 著者 Peng, C, Li, Y.H, Cheng, Y.S. 登録日 2019-04-17 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.297 Å) 主引用文献 Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity. Bioorg.Chem., 110, 2021

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