PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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7A9U	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide 分子名称: 1,2-ETHANEDIOL, 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide, Bromodomain-containing protein 4 著者 Chung, C. 登録日 2020-09-02 公開日 2020-10-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.444 Å) 主引用文献 A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands. Angew.Chem.Int.Ed.Engl., 59, 2020
5WRF	Crystal structure of dodecameric type II dehydroquinate dehydratase from Acinetobacter baumannii with unexplained connecting electron density between free cysteine residues of molecular pairs 分子名称: 1,2-ETHANEDIOL, 3-dehydroquinate dehydratase 著者 Iqbal, N, Singh, P.K, Kaur, P, Sharma, S, Singh, T.P. 登録日 2016-12-01 公開日 2016-12-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Crystal structure of dodecameric type II dehydroquinate dehydratase from Acinetobacter baumannii with unexplained connecting electron density between free cysteine residues of molecular pairs To Be Published
1VNA	PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING 分子名称: NEUROTOXIN 著者 Lee, W, Krishna, N.R. 登録日 1993-10-26 公開日 1994-01-31 最終更新日 2024-10-09 実験手法 SOLUTION NMR 主引用文献 Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing. Biochemistry, 33, 1994
6ZMT	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-03 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
1VPU	NMR SOLUTION STRUCTURE OF THE HIV-1 VPU CYTOPLASMIC DOMAIN, 9 STRUCTURES 分子名称: VPU PROTEIN 著者 Willbold, D, Hoffmann, S, Rosch, P. 登録日 1997-01-28 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Secondary structure and tertiary fold of the human immunodeficiency virus protein U (Vpu) cytoplasmic domain in solution. Eur.J.Biochem., 245, 1997
1VLO	Crystal structure of aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (np417381) from Escherichia coli k12 at 1.70 A resolution 分子名称: Aminomethyltransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2004-08-05 公開日 2004-09-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system (np417381) from Escherichia coli k12 at 1.70 A resolution To be published
7A5H	Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. 登録日 2020-08-21 公開日 2020-12-23 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
7A5F	Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... 著者 Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. 登録日 2020-08-21 公開日 2020-12-23 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
1VRP	The 2.1 Structure of T. californica Creatine Kinase Complexed with the Transition-State Analogue Complex, ADP-Mg 2+ /NO3-/Creatine 分子名称: (DIAMINOMETHYL-METHYL-AMINO)-ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, Creatine Kinase, ... 著者 Lahiri, S.D, Wang, P.F, Babbitt, P.C, McLeish, M.J, Kenyon, G.L, Allen, K.N. 登録日 2005-04-25 公開日 2005-05-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The 2.1 A Structure of Torpedo californica Creatine Kinase Complexed with the ADP-Mg(2+)-NO3(-)-Creatine Transition-State Analogue Complex Biochemistry, 41, 2002
6ZPX	Structure of Unliganded MgGH51 a-L-Arabinofuranosidase Crystal Type 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, MgGH51, ... 著者 McGregor, N.G.S, Davies, G.J. 登録日 2020-07-09 公開日 2020-11-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of a GH51 alpha-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi. Acta Crystallogr D Struct Biol, 76, 2020
6ZYS	Structure of IMP-1 with 2-Mercaptomethyl-thiazolidine D-syn-1b 分子名称: (2~{S},4~{S})-2-ethoxycarbonyl-5,5-dimethyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase IMP-1, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2020-08-02 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87000954 Å) 主引用文献 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-beta-lactamases. Chem Sci, 12, 2021
6ZPY	Structure of Arabinose-Bound MgGH51 a-L-Arabinofuranosidase Crystal Type 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, MgGH51, ... 著者 McGregor, N.G.S, Davies, G.J. 登録日 2020-07-09 公開日 2020-11-11 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Structure of a GH51 alpha-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi. Acta Crystallogr D Struct Biol, 76, 2020
3K66	X-ray crystal structure of the E2 domain of C. elegans APL-1 分子名称: Beta-amyloid-like protein 著者 Hoopes, J.T, Ha, Y. 登録日 2009-10-08 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site J.Biol.Chem., 285, 2010
5VNX	Crystal structure of an 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct 分子名称: 1,2-ETHANEDIOL, 8-amino-7-oxononanoate synthase, BENZAMIDINE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-05-01 公開日 2017-05-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct to be published
3JVR	Characterization of the Chk1 allosteric inhibitor binding site 分子名称: (1S)-1-(1H-benzimidazol-2-yl)ethyl (3,4-dichlorophenyl)carbamate, Serine/threonine-protein kinase Chk1 著者 Chen, P. 登録日 2009-09-17 公開日 2009-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Characterization of the CHK1 allosteric inhibitor binding site. Biochemistry, 48, 2009
7A5I	Structure of the human mitoribosome with A- P-and E-site mt-tRNAs 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... 著者 Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. 登録日 2020-08-21 公開日 2020-12-23 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
3JZI	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series 分子名称: 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase 著者 Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
6ZN5	SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-06 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
1W6B	Solution NMR Structure of a Long Neurotoxin from the Venom of the Asian Cobra, 20 Structures 分子名称: LONG NEUROTOXIN 1 著者 Talebzadeh-Farooji, M, Amininasab, M, Elmi, M.M, Naderi-Manesh, H, Sarbolouki, M.N. 登録日 2004-08-17 公開日 2004-12-22 最終更新日 2024-11-13 実験手法 SOLUTION NMR 主引用文献 Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy. Eur. J. Biochem., 271, 2004
1W91	crystal structure of 1,4-BETA-D-XYLAN XYLOHYDROLASE solve using anomalous signal from Seleniomethionine 分子名称: BETA-XYLOSIDASE 著者 Jakoncic, J, Shoham, G, Stojanoff, V. 登録日 2004-10-05 公開日 2006-02-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of 1,4-Beta-D-Xylan Xylohydrolase from Geobacillus Stearothermophilus. To be Published
7ABF	Human pre-Bact-1 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-09 最終更新日 2025-10-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
3JWE	Crystal structure of human mono-glyceride lipase in complex with SAR629 分子名称: 1-[bis(4-fluorophenyl)methyl]-4-(1H-1,2,4-triazol-1-ylcarbonyl)piperazine, MGLL protein 著者 Bertrand, T, Auge, F, Houtmann, J, Rak, A, Vallee, F, Mikol, V, Berne, P.F, Michot, N, Cheuret, D, Hoornaert, C, Mathieu, M. 登録日 2009-09-18 公開日 2010-01-26 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for human monoglyceride lipase inhibition. J.Mol.Biol., 396, 2010
1W9I	Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. 登録日 2004-10-13 公開日 2006-03-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-Function Analysis of Myosin II Backdoor Mutants To be Published
3J83	Heptameric EspB Rosetta model guided by EM density 分子名称: ESX-1 secretion-associated protein EspB 著者 Solomonson, M, DiMaio, F, Strynadka, N.C.J. 登録日 2014-09-30 公開日 2015-03-11 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (30 Å) 主引用文献 Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism. Structure, 23, 2015
1W9K	Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Morris, C.A, Coureux, P.-D, Wells, A.L, Houdusse, A, Sweeney, H.L. 登録日 2004-10-13 公開日 2006-03-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-Function Analysis of Myosin II Backdoor Mutants To be Published

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