3K66

X-ray crystal structure of the E2 domain of C. elegans APL-1

Summary for 3K66

Entry DOI	10.2210/pdb3k66/pdb
Related	1RW6 3K6B
Descriptor	Beta-amyloid-like protein (2 entities in total)
Functional Keywords	x-ray crystal structure, amyloid precursor protein, heparin binding, alternative splicing, amyloid, developmental protein, differentiation, glycoprotein, membrane, neurogenesis, transmembrane, cell adhesion
Biological source	Caenorhabditis elegans (nematode)
Cellular location	Membrane ; Single-pass type I membrane protein : Q10651
Total number of polymer chains	1
Total formula weight	28516.44
Authors	Hoopes, J.T.,Ha, Y. (deposition date: 2009-10-08, release date: 2009-11-10, Last modification date: 2024-02-21)
Primary citation	Hoopes, J.T.,Liu, X.,Xu, X.,Demeler, B.,Folta-Stogniew, E.,Li, C.,Ha, Y. Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site J.Biol.Chem., 285:2165-2173, 2010 Cited by PubMed: 19906646 DOI: 10.1074/jbc.M109.018432 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation