3K6B
X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)
Summary for 3K6B
Entry DOI | 10.2210/pdb3k6b/pdb |
Related | 1RW6 3K66 |
Descriptor | Beta-amyloid-like protein, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | x-ray crystal structure, amyloid precursor protein, heparin binding, alternative splicing, amyloid, developmental protein, differentiation, glycoprotein, membrane, neurogenesis, transmembrane, cell adhesion |
Biological source | Caenorhabditis elegans (nematode) |
Total number of polymer chains | 1 |
Total formula weight | 29016.85 |
Authors | Hoopes, J.T.,Ha, Y. (deposition date: 2009-10-08, release date: 2009-11-10, Last modification date: 2023-09-06) |
Primary citation | Hoopes, J.T.,Liu, X.,Xu, X.,Demeler, B.,Folta-Stogniew, E.,Li, C.,Ha, Y. Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site J.Biol.Chem., 285:2165-2173, 2010 Cited by PubMed: 19906646DOI: 10.1074/jbc.M109.018432 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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