PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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1GAZ	Crystal Structure of Mutant Human Lysozyme Substituted at the Surface Positions 分子名称: LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-07-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of amino acid residues at turns in the conformational stability and folding of human lysozyme. Biochemistry, 39, 2000
7C65	Crystal structure of thioredoxin m1 分子名称: SODIUM ION, Thioredoxin M1, chloroplastic 著者 Kurisu, G, Juniar, L, Tanaka, H. 登録日 2020-05-21 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity. Protein Sci., 29, 2020
5K3F	Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - His280Asn/Fluoroacetate - Cocrystallized - Single Protomer Reacted with Ligand 分子名称: CHLORIDE ION, Fluoroacetate dehalogenase 著者 Mehrabi, P, Kim, T.H, Prosser, S.R, Pai, E.F. 登録日 2016-05-19 公開日 2017-02-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 The role of dimer asymmetry and protomer dynamics in enzyme catalysis. Science, 355, 2017
5LX8	Crystal structure of BT1762 分子名称: SODIUM ION, SULFATE ION, SusD homolog 著者 Basle, A. 登録日 2016-09-20 公開日 2016-12-14 最終更新日 2017-08-30 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature, 541, 2017
6C07	Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum 分子名称: CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ... 著者 Ohren, J.F, Viola, R.E. 登録日 2017-12-28 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum. Acta Crystallogr F Struct Biol Commun, 75, 2019
6WJT	2.0 Angstrom Resolution Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 in Complex with S-Adenosyl-L-Homocysteine 分子名称: 2'-O-methyltransferase, FORMIC ACID, Non-structural protein 10, ... 著者 Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-04-14 公開日 2020-04-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design. Sci.Signal., 13, 2020
5LZQ	Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sodium ion 分子名称: IMIDODIPHOSPHORIC ACID, K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, ... 著者 Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. 登録日 2016-10-01 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.495 Å) 主引用文献 Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism. Nat Commun, 7, 2016
6HT6	Crystal structure of glutathione transferase Omega 2S from Trametes versicolor in complex with 2,4-dihydroxybenzophenone 分子名称: Glutathione S-transferase omega 2S, MAGNESIUM ION, [2,4-bis(oxidanyl)phenyl]-phenyl-methanone 著者 Schwartz, M, Favier, F, Didierjean, C. 登録日 2018-10-03 公開日 2018-10-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.671 Å) 主引用文献 Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor. Sci Rep, 8, 2018
7AUC	Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Chen, X, Oliver, A.W. 登録日 2020-11-02 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
6TU7	Structure of PfMyoA decorated Plasmodium Act1 filament 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... 著者 Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. 登録日 2020-01-03 公開日 2021-01-13 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 High-resolution structures of malaria parasite actomyosin and actin filaments. Plos Pathog., 18, 2022
6BYS	Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PRKAc alpha 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P. 登録日 2017-12-21 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.75 Å) 主引用文献 Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha. Structure, 27, 2019
6TQK	Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ... 著者 Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. 登録日 2019-12-16 公開日 2020-11-04 最終更新日 2021-03-03 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
6NG9	Crystal structure of human CD160 分子名称: CD160 antigen 著者 Liu, W, Bonanno, J, Almo, S.C. 登録日 2018-12-21 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Structural Basis of CD160:HVEM Recognition. Structure, 27, 2019
7AO9	Structure of the core MTA1/HDAC1/MBD2 NURD deacetylase complex 分子名称: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... 著者 Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. 登録日 2020-10-14 公開日 2020-11-11 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
6CG7	mouse cadherin-22 EC1-2 adhesive fragment 分子名称: CALCIUM ION, Cadherin-22 著者 Brasch, J, Harrison, O.J, Shapiro, L. 登録日 2018-02-19 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior. Cell Rep, 23, 2018
5MQI	Crystal structure of the N-terminal domain of human Timeless 分子名称: Protein timeless homolog,Protein timeless homolog, SULFATE ION 著者 Holzer, S, Kilkenny, M.L, Pellegrini, L. 登録日 2016-12-20 公開日 2017-03-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.847 Å) 主引用文献 Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin. Nucleic Acids Res., 45, 2017
6CGS	mouse cadherin-7 EC1-2 adhesive fragment 分子名称: CALCIUM ION, Cadherin-7, GLYCEROL 著者 Brasch, J, Harrison, O.J, Kaczynska, A, Shapiro, L. 登録日 2018-02-20 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior. Cell Rep, 23, 2018
8HM0	F8-A22-E4 complex of MPXV in trimeric form 分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R 著者 Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. 登録日 2022-12-02 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
7JO9	1:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
6TT3	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6. 分子名称: (2~{S})-1-[(2~{S})-2-[[(1~{S})-1-[(2~{S})-1-[(2~{S})-2-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]-2-oxidanyl-2-oxidanylidene-ethyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
8HLZ	F8-A22-E4 complex of MPXV in hexameric form 分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R 著者 Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. 登録日 2022-12-02 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
7JPS	ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), ... 著者 Jaremko, M.J, Joshua-Tor, L. 登録日 2020-08-09 公開日 2020-09-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures. Elife, 9, 2020
6TMJ	Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, rotor-stator model 分子名称: ATP synthase subunit delta, ATP synthase subunit epsilon, ATP synthase subunit gamma, ... 著者 Muhleip, A, Kock Flygaard, R, Amunts, A. 登録日 2019-12-04 公開日 2020-12-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nat Commun, 12, 2021
5MG7	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-p53R2) 分子名称: Cellular tumor antigen p53, DNA, ZINC ION 著者 Rozenberg, H, Braeuning, B, Golovenko, D, Shakked, Z. 登録日 2016-11-21 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
8RZW	A fragment-based inhibitor of SHP2 分子名称: 3,5-bis(chloranyl)pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024

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