6TT3

Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6.

Summary for 6TT3

Entry DOI	10.2210/pdb6tt3/pdb
Descriptor	Angiotensin-converting enzyme, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... (16 entities in total)
Functional Keywords	angiotensin-1 converting enzyme, ace inhibitor, diprolyl, metalloprotease, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	150705.08
Authors	Cozier, G.E.,Acharya, K.R. (deposition date: 2019-12-23, release date: 2020-04-01, Last modification date: 2024-01-24)
Primary citation	Cozier, G.E.,Lubbe, L.,Sturrock, E.D.,Acharya, K.R. ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477:1241-1259, 2020 Cited by PubMed: 32195541 DOI: 10.1042/BCJ20200060 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation